Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 2 Issue: 3, May

Graphical Abstracts

Volume:2   Issue: 3
Pp: v-V

DOI: 10.2174/157018081050203000v
Published on: 01 March, 2012

Role of 2-Antiplasmin in Cardiovascular System

Volume:2   Issue: 3
Pp: 172-176
En Shu, Hiroyuki Matsuno, Yasuo Kitajima and Osamu Kozawa
DOI: 10.2174/1570180053765129
Published on: 01 March, 2012

Peptide Mimetic Factor VIIa Inhibitor: Importance of Hydrophilic Pocket in S2 Site to Improve Selectivity Against Thrombin

Volume:2   Issue: 3
Pp: 177-181
S. Kadono, A. Sakamoto, Y. Kikuchi, M. Oh-eda, N. Yabuta, T. Koga, K. Hattori, T. Shiraishi, M. Haramura and H. Kodama
DOI: 10.2174/1570180053765200
Published on: 01 March, 2012

A Cellular ELISA to Screen Lectin-Like Compounds for Cancer Cell Binding

Volume:2   Issue: 3
Pp: 182-188
C- P. Chang, W- C. Cheng and H- Y. Lei
DOI: 10.2174/1570180053765228
Published on: 01 March, 2012

A Facile Synthesis of C2-Substituted Pyrrolo[2,3-f]quinolines with Cytotoxic Activity

Volume:2   Issue: 3
Pp: 189-192
Andrew Tsotinis, Margarita Vlachou, Spyridon Zouroudis, Andras Jeney, Ferenc Timar, David E. Thurston and Christos Roussakis
DOI: 10.2174/1570180053765075
Published on: 01 March, 2012

Impact of Oral Administration of the Surface-Active Excipient Solutol HS 15 on the Pharmacokinetics of Intravenously Administered Colchicine

Volume:2   Issue: 3
Pp: 193-195
B. Bittner, R. C. Bravo Gonzalez, I. Walter and J. Huwyler
DOI: 10.2174/1570180053765165
Published on: 01 March, 2012

Preliminary In vitro Results Indicating Tartronic Acids as Aspartic Acid Mimetics in Vitronectin Receptor Antagonists: Evidence for Increased Hydroxyapatite Affinity

Volume:2   Issue: 3
Pp: 201-204
Diane B. Hauze, Kenneth L. Kees, Charles W. Mann, Horace Fletcher III, Richard Murrills, Jeanne Matteo, Frederick Bex, Bheem Bhat and Valerie Coleburn
DOI: 10.2174/1570180053765110
Published on: 01 March, 2012

Pyrazinobenzodiazepines as Potent Nonpeptide Vasopressin Receptor Antagonists

Volume:2   Issue: 3
Pp: 219-223
Jay M. Matthews, Dennis J. Hlasta, Patricia Andrade-Gordon, Keith T. Demarest, Eric Ericson, Joseph W. Gunnet, William Hageman, Richard Look, John B. Moore and Bruce E. Maryanoff
DOI: 10.2174/1570180053765183
Published on: 01 March, 2012

Synthesis and Characterization of a Novel Protein Tyrosine Phosphatase Inhibitor, 2-(Cyclobutylamino)- N- (2-Furylmethyl)-2-Thioxoacetamide

Volume:2   Issue: 3
Pp: 224-227
Y. Kobayashi-Matsunaga, T. Ishii, T. Hamaguchi, H. Osada and M. Sato
DOI: 10.2174/1570180053765101
Published on: 01 March, 2012

Expression of α6β4 and α3β1 Integrins in Bullous Pemphigoid and Pemphigus Vulgaris

Volume:2   Issue: 3
Pp: 228-231
G. Giannelli, C. Foti, C. Divella, F. Marinosci, D. Bonamonte and S. Antonaci
DOI: 10.2174/1570180053765084
Published on: 01 March, 2012

Molecular Modeling for Quantitative Analysis of Molecular Interaction†

Volume:2   Issue: 3
Pp: 232-238
Toshihiko Hanai
DOI: 10.2174/1570180053765192
Published on: 01 March, 2012

Ascorbic Acid as Modulator of Immune Function in Sepsis

Volume:2   Issue: 3
Pp: 239-244
V. M. Victor
DOI: 10.2174/1570180053765219
Published on: 01 March, 2012

Difficulties in the Management of Frontal Dementia: Therapeutics Strategies

Volume:2   Issue: 3
Pp: 245-249
Rita Moretti, Paola Torre, Rodolfo M. Antonello, Tatiana Cattaruzza and Giuseppe Cazzato
DOI: 10.2174/1570180053765147
Published on: 01 March, 2012

Design of a New Phosphate Binder, Anion Exchange Resin, Based on Microcalorimeter Measurements

Volume:2   Issue: 3
Pp: 250-254
Hiroyoshi Inoue and Sho-ichi Yamagishi
DOI: 10.2174/1570180053765138
Published on: 01 March, 2012