Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 17 Issue: 8, August 2020

Meet Our Editorial Board Member free to download

Volume:17   Issue: 8
Pp: 939-939
Ahmed Kamal
DOI: 10.2174/157018081708200629121931
Published on: 29 June, 2020

Novel Coronavirus (COVID-19) Outbreak: Hope and Search for Effective Therapeutic Agent free to download

Volume:17   Issue: 8
Pp: 940-942
Saurabh Kumar*
DOI: 10.2174/1570180817999200612095513
Published on: 11 June, 2020

Structure-based Drug Design Strategies in the Development of Small Molecule Inhibitors Targeting Bcl-2 Family Proteins open access plus

Volume:17   Issue: 8
Pp: 943-953
Zhe Yin, Donglin Yang, Jun Wang and Yuequan Jiang*
DOI: 10.2174/1570180817666200213114759
Published on: 12 February, 2020

Anticholinesterase Activity of Cinnamic Acids Derivatives: In Vitro, In Vivo Biological Evaluation, and Docking Study

Volume:17   Issue: 8
Pp: 965-982
Shahrzad Ghafary, Hamid Nadri, Mohammad Mahdavi, Alireza Moradi, Tahmineh Akbarzadeh, Mohammad Sharifzadeh, Najmeh Edraki, Farshad Homayouni Moghadam and Mohsen Amini*
DOI: 10.2174/1570180817666191224094049
Published on: 23 December, 2019

Biological Evaluation and Molecular Modeling of 3,4-dihydropyrimidine- 2(1H)-one Derivatives as Cytotoxic Agents on Breast Cancer In Vitro

Volume:17   Issue: 8
Pp: 983-992
Hoda Sharifi, Ahmad Ebadi* and Meysam Soleimani*
DOI: 10.2174/1570180817666200203125010
Published on: 03 February, 2020

JAK/STAT3 Pathway in Human Intestinal Epithelial Cells During Trefoil Factor 3(TFF3) Mediated Cell Migration

Volume:17   Issue: 8
Pp: 993-1000
Mengmeng Zhuang, Juan Le, Bo Zhu, Wenwen Zhang, Hao Yan, Pan Zhang, Ting Wang and Yong Sun*
DOI: 10.2174/1570180817666200204104420
Published on: 03 February, 2020

Rational Design of Hyper-glycosylated Human Chorionic Gonadotropin Analogs (A Bioinformatics Approach)

Volume:17   Issue: 8
Pp: 1001-1014
Zahra Nabizadeh, Zarrin Minuchehr* and Ali Akbar Shabani*
DOI: 10.2174/1570180817666200225101938
Published on: 24 February, 2020

Synthesis, Docking, in silico ADMET and Pharmacological Evaluation of Some N-acetyl Pyrazole and Quinoline Conjugates

Volume:17   Issue: 8
Pp: 1015-1026
Nargisbano Ayyub Peerzade, Shravan Yegu Jadhav*, Raghunath Bhikaji Bhosale, Amol Anantrao Kulkarni and Bhushan Dnyandeo Varpe
DOI: 10.2174/1570180817666200228123347
Published on: 28 February, 2020

Structure-based Virtual Screening Approach for the Discovery of Potent Inhibitors of Aminoglycoside 6'-N-Acetyltransferase Type Ib [AAC(6')-Ib] against K. pneumoniae Infections

Volume:17   Issue: 8
Pp: 1027-1035
Reaz Uddin*, Bushra Siraj, Sidra Rafi, Syed Sikander Azam and Abdul Wadood
DOI: 10.2174/1570180817666200108095912
Published on: 07 January, 2020

Studies on the IC50 of Metabolically Stable 1-(3,3-diphenylpropyl)- piperidinyl Amides and Ureas as Human CCR5 Receptor Antagonists Based on QSAR open access plus

Volume:17   Issue: 8
Pp: 1036-1046
Yutao Zhao, Xiaoqian Liu, Jing Ouyang, Yan Wang, Shanyu Xu, Dongdong Tian and Hongzong Si*
DOI: 10.2174/1570180817666200320105725
Published on: 19 March, 2020

Synthesis, Characterization, Antimicrobial, Anti-tubercular, Antioxidant Activities and Docking Simulations of Derivatives of 2-(pyridin-3-yl)-1Hbenzo[ d]imidazole and 1,3,4-Oxadiazole Analogy

Volume:17   Issue: 8
Pp: 1047-1059
Shipra Bhati, Vijay Kumar*, Simranjeet Singh and Joginder Singh*
DOI: 10.2174/1570180816666191122105313
Published on: 21 November, 2019

Lapatinib as a Dual Tyrosine Kinase Inhibitor Unexpectedly Activates Akt in MDA-MB-231 Triple-Negative Breast Cancer Cells

Volume:17   Issue: 8
Pp: 1060-1063
Parham Jabbarzadeh Kaboli * and King-Hwa Ling
DOI: 10.2174/1570180817666200212125658
Published on: 12 February, 2020