Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 17 Issue: 10, October 2020



Meet Our Editorial Board Member free to download

Volume:17   Issue: 10
Pp: 1197-1197
Eng-Ang Ling
DOI: 10.2174/157018081710200924092601
Published on: 23 September, 2020



Anti-inflammatory Augmentation Therapy in Obsessive-compulsive Disorder: A Review

Volume:17   Issue: 10
Pp: 1198-1205
Hanie Ghasemi, Homa Nomani, Amirhossein Sahebkar* and Amir Hooshang Mohammadpour*
DOI: 10.2174/1570180817999200520122910
Published on: 20 May, 2020




Fingerprint-based 2D-QSAR Models for Predicting Bcl-2 Inhibitors Affinity

Volume:17   Issue: 10
Pp: 1206-1215
Said Byadi, Hachim Mouhi Eddine, Karima Sadik, Črtomir Podlipnik and Aziz Aboulmouhajir*
DOI: 10.2174/1570180817999200414155403
Published on: 14 April, 2020




Synthesis, Molecular Docking and α-Glucosidase Inhibitory Activity Study of 2,4,6-triaryl Pyrimidine Derivatives

Volume:17   Issue: 10
Pp: 1216-1226
Mohammed Hussen Bule , Roghaieh Esfandyari, Tadesse Bekele Tafesse, Mohsen Amini*, Mohammad Ali Faramarzi and Mohammad Abdollahi
DOI: 10.2174/1570180817666200103130536
Published on: 03 January, 2020




Novel Benzimidazole Derivatives: Cytotoxic and Apoptotic Properties on Lung Cancer Cell Line

Volume:17   Issue: 10
Pp: 1227-1236
Leyla Yurttaş*, Gülşen Akalin Çiftçi, Mehmet Onur Aksoy and Şeref Demirayak
DOI: 10.2174/1570180817999200513091613
Published on: 12 May, 2020




Experimental Study of Therapeutic Efficacy of the Topical Preparation «Kourochitin» in Skin Allergy

Volume:17   Issue: 10
Pp: 1237-1244
Anna Anatolievna Klimovich*, Olga Nikolaevna Styshova, Alexander Mikhailovich Popov, Tatiana Vladimirovna Moskvina*, Alexander Vasilevich Tsybulsky, Dmitry Albertovich Derunov and Valentin Aronovich Stonik
DOI: 10.2174/1570180817666200316155643
Published on: 16 March, 2020




Molecular Docking of 4-ethoxychalcones on Oxidoreductase/Pirin Inhibitors and Cytotoxic Evaluation on Breast/Skin Cancer Cell Lines

Volume:17   Issue: 10
Pp: 1245-1260
Kishori Ramachandra Harshitha, Balladka Kunhanna Sarojini*, Badiadka Narayana, Anupam Glorious Lobo and Bhuvanesh Sukhlal Kalal
DOI: 10.2174/1570180817666200129143803
Published on: 29 January, 2020




Effect of Cabergoline on Cognitive Impairments in Transgenic Drosophila Model of Parkinson’s Disease

Volume:17   Issue: 10
Pp: 1261-1269
Yasir Hasan Siddique*, Rahul, Mantasha Idrisi and Mohd. Shahid
DOI: 10.2174/1570180817999200514100917
Published on: 13 May, 2020




Design, Synthesis and Biological Evaluation of Dimethyl Cardamonin (DMC) Derivatives as P-glycoprotein-mediated Multidrug Resistance Reversal Agents

Volume:17   Issue: 10
Pp: 1270-1282
Ximeng Shi, Yuyu Zhao, Licheng Zhou, Huanhuan Yin, Jianwen Liu* and Lei Ma*
DOI: 10.2174/1570180817999200531162015
Published on: 31 May, 2020




Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors

Volume:17   Issue: 10
Pp: 1283-1292
Cem Yamali*, Halise Inci Gul*, Tahir Cakir, Yeliz Demir and Ilhami Gulcin
DOI: 10.2174/1570180817999200520123510
Published on: 20 May, 2020




Molecular Docking and QSAR Studies of Coumarin Derivatives as NMT Inhibitors: Simple Structural Features as Potential Modulators of Antifungal Activity

Volume:17   Issue: 10
Pp: 1293-1308
Sapna Jain Dabade, Dheeraj Mandloi* and Amritlal Bajaj
DOI: 10.2174/1570180817999200617105711
Published on: 16 June, 2020




Molecular Insights into the Interaction of Ursolic Acid and Cucurbitacin from Colocynth with Therapeutic Targets of Mycobacterium tuberculosis

Volume:17   Issue: 10
Pp: 1309-1318
Mohammad Ajmal Ali*, Mohammad Abul Farah*, Joongku Lee, Khalid M. Al-Anazi and Fahad M.A. Al-Hemaid
DOI: 10.2174/1570180817999200514102750
Published on: 13 May, 2020




Preliminary Analysis of Anti-proliferative, Apoptotic, and Anti-migratory Effects llw-3-6 in Skov-3 Ovarian Cystadenocarcinoma Cell Line open access plus

Volume:17   Issue: 10
Pp: 1319-1324
Rosalind Gregory-Bass and Leyte L. Winfield*
DOI: 10.2174/1570180817666200129142949
Published on: 29 January, 2020




Drug Re-purposing from SARS-CoV Led the Identification of Potential Candidate Drug Target and Alternate Drug Molecules Against SARSCoV- 2

Volume:17   Issue: 10
Pp: 1325-1327
PV Parvati Sai Arun*, Razak Hussain, Yusuf Akhter, Mandava Venkata Basaveswara Rao, Perugu Shyam and Sailu Yellaboina
DOI: 10.2174/1570180817999200730190600
Published on: 30 July, 2020