Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 16 Issue: 6, June 2019

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Volume:16   Issue: 6
Pp: 607-607
Dimitra Hadjipavlou-Litina
DOI: 10.2174/157018081606190503093903
Published on: 02 May, 2019

Virtual Screening, Docking, Synthesis and Bioactivity Evaluation of Thiazolidinediones as Potential PPARγ Partial Agonists for Preparation of Antidiabetic Agents

Volume:16   Issue: 6
Pp: 608-617
Beina Zhang, Mao Shu*, Chunmei Xu, Chunhong An, Rui Wang and Zhihua Lin*
DOI: 10.2174/1570180815666180827123512
Published on: 27 August, 2018

Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents

Volume:16   Issue: 6
Pp: 618-624
Veerasamy Ravichandran*, Sivadasan Shalini, Krishnan Suresh Kumar, Harish Rajak and Ram Kishore Agrawal
DOI: 10.2174/1570180815666180801120440
Published on: 01 August, 2018

Virtual Screening of Henna Compounds Library for Discovery of New Leads against Human Thymidine Phosphorylase, an Overexpressed Factor of Hand-Foot Syndrome

Volume:16   Issue: 6
Pp: 625-636
Davood Khodabakhshi-Javinani, Azadeh Ebrahim-Habibi*, Minoo Afshar and Latifeh Navidpour*
DOI: 10.2174/1570180815666180816123233
Published on: 16 August, 2018

In Silico Prediction and Validation of Oxygen-Regulated Protein N-myc Downstream Regulated Gene 3 and Virtual Screening of Competitive Inhibitors of L-Lactate as Therapeutics

Volume:16   Issue: 6
Pp: 637-644
Hongyu Cao, Yanhua Wu, Xingzhi Zhou, Xuefang Zheng and Ge Jiang *
DOI: 10.2174/1570180815666180816130621
Published on: 16 August, 2018

New Procaspase Activating Compound (PAC-1) Like Molecules as Potent Antitumoral Agents Against Lung Cancer

Volume:16   Issue: 6
Pp: 645-655
Leyla Yurttaş*, Ömer Öztürk and Zerrin Cantürk
DOI: 10.2174/1570180815666180926113040
Published on: 26 September, 2018

Novel 1,3,4-Oxadiazole Fused Thiadiazole Derivatives: Synthesis and study of Anticancer Activities

Volume:16   Issue: 6
Pp: 656-662
Zanjam Spandana, Reddymasu Sreenivasulu, Tadigiri MalathiRekha and Mandava Venkata Basaveswara Rao*
DOI: 10.2174/1570180816666181031125946
Published on: 31 October, 2018

Synthesis and Anti-Tumor Activity Evaluation of Novel 7-Fluoro-4-(1- Piperazinyl) Quinolines

Volume:16   Issue: 6
Pp: 663-669
Dan Liu*, Aiqi Xue, Zhixin Liu, Yi Zhang, Penghui Peng and Haifeng Wang
DOI: 10.2174/1570180815666180820131036
Published on: 20 August, 2018

Exploring Energy Profiles of Protein-Protein Interactions (PPIs) Using DFT Method

Volume:16   Issue: 6
Pp: 670-677
Sanket Bapat, Renu Vyas* and Muthukumarasamy Karthikeyan
DOI: 10.2174/1570180815666180815151141
Published on: 15 August, 2018

Design and Synthesis of the Diazirine-based Clickable Photo-affinity Probe Targeting Sphingomyelin Synthase 2 open access plus

Volume:16   Issue: 6
Pp: 678-684
Penghui Wang, Zhining Li, Lulu Jiang, Lu Zhou* and Deyong Ye*
DOI: 10.2174/1570180816666181106154601
Published on: 06 November, 2018

Synthesis, Formulation and Analytical Method Validation of Rutin Derivative

Volume:16   Issue: 6
Pp: 685-695
Murad Abualhasan*, Mohyeddin Assali, Nidal Jaradat and Tala Sarhan
DOI: 10.2174/1570180816666181108114706
Published on: 07 November, 2018

Action of Thioglycosides of 1,2,4-Triazoles and Imidazoles on the Oxidative Stress and Glycosidases in Mice with Molecular Docking

Volume:16   Issue: 6
Pp: 696-710
Mahmoud Balbaa*, Doaa Awad, Ahmad Abd Elaal, Shimaa Mahsoub, Mayssaa Moharram, Omayma Sadek, Nadjet Rezki, Mohamed Reda Aouad, Mohamed El-Taher Ibrahim Badawy and El Sayed Helmy El Ashry
DOI: 10.2174/1573413715666181212150955
Published on: 12 December, 2018