Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 16 Issue: 12, December 2019

Meet Our Associate Editor free to download

Volume:16   Issue: 12
Pp: 1303-1304
Bimal Krishna Banik
DOI: 10.2174/157018081612191108153022
Published on: 08 November, 2019

Monobactams: A Unique Natural Scaffold of Four-Membered Ring Skeleton, Recent Development to Clinically Overcome Infections by Multidrug- Resistant Microbes

Volume:16   Issue: 12
Pp: 1305-1320
Abdel Nasser El-Shorbagi* and Sachin Chaudhary
DOI: 10.2174/1570180816666190516113202
Published on: 16 May, 2019

Effects of Acute and Chronic Treatment of Novel Psychotropic Drug, 8- (Trifluoromethyl)-1, 2, 3, 4, 5-benzopentathiepin-6-amine Hydrochloride (TC-2153), on the Behavior of Zebrafish (Danio Rerio): A Comparison with Fluoxetine

Volume:16   Issue: 12
Pp: 1321-1328
Alexander Kulikov, Nadezhda Sinyakova, Elizabeth Kulikova, Tatyana Khomenko, Nariman Salakhutdinov, Victor Kulikov and Konstantin Volcho*
DOI: 10.2174/1570180816666190221162952
Published on: 21 February, 2019

Biology-oriented Drug Synthesis (BIODS), Structural Characterization and Bioactivities of Novel Albendazole Derivatives

Volume:16   Issue: 12
Pp: 1329-1338
Momin Khan*, Shahid Khan, Uzma Salar, Khalid Mohammed Khan, Gauhar Rehman, Naeem Gul and Iltaf Khan
DOI: 10.2174/1570180816666190221163641
Published on: 21 February, 2019

Baicalin-induced Cytotoxicity and Apoptosis in Multidrug-resistant MC3/5FU Mucoepidermoid Carcinoma Cell Line

Volume:16   Issue: 12
Pp: 1339-1347
Xiaofang Xu, Qihong Li, Kaitao Yu*, Ghulam Murtaza* and Bin Liu*
DOI: 10.2174/157018081210151012121717
Published on: 08 January, 2019

Design, Synthesis and Bioactivity of Core 1 O-glycan and its Derivative on Human Gut Microbiota

Volume:16   Issue: 12
Pp: 1348-1353
Huanhuan Qu*, Baixue Li, Jingyi Yang, Huaiwen Liang, Meixia Li and Kan Ding*
DOI: 10.2174/1570180816666181218143207
Published on: 18 December, 2018

Anticancer Potential of Pulicaria crispa Extract on Human Breast Cancer MDA-MB-231 Cells

Volume:16   Issue: 12
Pp: 1354-1359
Ibrahim Omar Barnawi and Imran Ali*
DOI: 10.2174/1570180816666190712110224
Published on: 12 July, 2019

Synthesis and Antimicrobial Activity of Adamantyl Substituted Pyridoxine Derivatives

Volume:16   Issue: 12
Pp: 1360-1369
Rail Khaziev, Nikita Shtyrlin, Roman Pavelyev, Raushan Nigmatullin, Raylya Gabbasova, Denis Grishaev, Anna Shtro, Anastasia Galochkina , Yulia Nikolaeva , Tatiana Vinogradova , Olga Manicheva, Marine Dogonadze, Oleg Gnezdilov , Evgenii Sokolovich, Petr Yablonskiy, Konstantin Balakin and Yurii Shtyrlin*
DOI: 10.2174/1570180816666190911150705
Published on: 11 September, 2019

The Antiviral Effects of Sodium Phenylbutyrate Against BoHV-1 Infection In Vitro

Volume:16   Issue: 12
Pp: 1370-1377
Xinye Chen, Guoqiang Zhu* and Liqian Zhu*
DOI: 10.2174/1570180816666190222155958
Published on: 22 February, 2019

Design, Synthesis and Biological Evaluation of Camptothecin Conjugated with NSAIDs as Novel Dual-actin Antitumor Agents

Volume:16   Issue: 12
Pp: 1378-1386
Xingchen Cai, Weiwei Huang, Yi Huang, Lihua Xia, Miao Liu, Mengke Wang, Wenchao Wang and Qingyong Li*
DOI: 10.2174/1570180816666190221103257
Published on: 20 February, 2019

Challenges in the Discovery and Optimization of mGlu2/4 Heterodimer Positive Allosteric Modulators open access plus

Volume:16   Issue: 12
Pp: 1387-1394
Mark Gallant Fulton, Matthew Thomas Loch, Caroline Anne Cuoco, Alice Lambert Rodriguez, Emily Days, Paige Newton Vinson, Krystian Andrezej Kozek, Charles David Weaver, Anna Louise Blobaum, Peter Jeffrey Conn, Colleen Marie Niswender* and Craig William Lindsley*
DOI: 10.2174/1570180815666181017131349
Published on: 17 October, 2018

Acknowledgements to Reviewers free to download

Volume:16   Issue: 12
Pp: 1395-1396

DOI: 10.2174/157018081612191108153118
Published on: 08 November, 2019