Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:15   Issue: 8
Pp: 813-813
Bimal Krishna Banik
DOI: 10.2174/157018081508180621092335



2-Indolinone Derivatives as Potent Urease Inhibitors

Volume:15   Issue: 8
Pp: 814-821
Momin Khan*, Muhammad Yousaf, Abdul Wadood, Zahid Hussain, Muhammad Naeem, Khair Zaman, Sana Shah, Khalid Mohammed Khan and Shahnaz Perveen
DOI: 10.2174/1570180814666171116154110




Reactivation Potential of Novel More Lipophilic Pralidoxime Analogs

Volume:15   Issue: 8
Pp: 822-827
Martina Hrabinova, Jan Misik, Daniel Jun and Kamil Kuca*
DOI: 10.2174/1570180814666171013163019




Synthesis, Antimicrobial Effect and Surface Properties of Hydroxymethylsubstituted Pyridinium Salts

Volume:15   Issue: 8
Pp: 828-842
Jan Marek, Vera Joskova, Rafael Dolezal, Ondrej Soukup, Marketa Benkova, Alena Fucikova, David Malinak, Vanda Bostikova and Kamil Kuca*
DOI: 10.2174/1570180814666171110142233




Inhibitory Effects of 1,4-disubstituted Thiosemicarbazide Derivatives on Streptococcus mutans and Streptococcus sanguinis Mono-species Biofilms

Volume:15   Issue: 8
Pp: 843-850
Malgorzata Miazga-Karska, Maciej Wos, Agnieszka A. Kaczor, Anna Pachuta-Stec, Grazyna Ginalska and Monika Pitucha*
DOI: 10.2174/1570180814666171012164241




Barbaterpene and Barbatusterol, New Constituents from Plectranthus barbatus Growing in Saudi Arabia

Volume:15   Issue: 8
Pp: 851-856
Musarat Amina*, Nawal M. Al Musayeib *, Mansour S. Al-Said, Rania A. Al-Zahrani, Sabrin R.M. Ibrahim and Gamal A. Mohamed
DOI: 10.2174/1570180814666171120161340




Synthesis, Characterization, Biological Activity of Novel 1H-benzo[f]- chromene and 12H-benzo[f]chromeno[2,3-d]pyrimidine Derivatives

Volume:15   Issue: 8
Pp: 857-865
Heba K. Abd El-Mawgoud, Hebat Allah M. Radwan, Fatma El-Mariah and Ahmed M. El-Agrody*
DOI: 10.2174/1570180814666171027160854




Design, Synthesis and In vitro Evaluation of Piperazine Incorporated Novel Anticancer Agents

Volume:15   Issue: 8
Pp: 866-874
Mahaveer Singh*, Hemant R. Jadhav* and Amit Kumar
DOI: 10.2174/1570180815666171211161501




Synthesis, Biological Evaluation and Docking Studies of N-(2-benzamido feruloyl) Aryl Hydrazone Analogues

Volume:15   Issue: 8
Pp: 875-886
M. Soujanya *, G. Rajitha, A. Umamaheswari and K. Sudheer Kumar
DOI: 10.2174/1570180814666171026161041




Antihelminthic Activity of Some 2-Substituted Thieno[2,3-d]pyrimidin-4-ones

Volume:15   Issue: 8
Pp: 887-894
Anelia Mavrova, Stefan Dimov, Dimitar Vuchev, Kameliya Anichina and Denitsa Yancheva*
DOI: 10.2174/1570180814666171027161555




Enhanced Antibacterial Activity of Endo-nortropine Substituted (C-7) Fluoroquinolones Against V. cholerae, S. aureus and B. subtilis

Volume:15   Issue: 8
Pp: 895-904
Ramkrushna Ashok Salunke, Chandni Sidhu, Ashok Kumar, Anil Kumar Pinnaka, Baldev Raj Bansal and Manmohan Chhibber*
DOI: 10.2174/1570180814666171026162304




Rational Design, Synthesis and Biological Evaluation of Novel Derivatives Based on in vivo Metabolism of Natural Product β-elemene

Volume:15   Issue: 8
Pp: 905-912
Renren Bai*, Xiaokang Jie, Eric Salgado, Jian Sun, Yao Zhu, Thomas Pickel, Yuanyuan Xie, Jichao Chen and Jinyi Xu*
DOI: 10.2174/1570180814666171108093021