Letters in Drug Design & Discovery


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Design, Synthesis, Characterization and Antitubercular Screening of some New 1,2,4-Triazoles Derived from Isonicotinic Acid Hydrazides

Volume:15   Issue: 5
Pp: 451-462
Vaibhav Rajoriya, Varsha Kashaw* and Sushil K. Kashaw*
DOI: 10.2174/1570180814666170727143806

Synthesis, Biological Evaluation, Molecular Docking Study and Acute Oral Toxicity Study of Coupled Imidazole-Pyrimidine Derivatives

Volume:15   Issue: 5
Pp: 475-487
Shailee V. Tiwari, Anna P.G. Nikalje*, Deepak K. Lokwani, Aniket P. Sarkate and Kizukala Jamir
DOI: 10.2174/1570180814666170704101817

Computational Approach to the Discovery of Phytochemical Molecules with Therapeutic Potential Targets to the PKCZ protein

Volume:15   Issue: 5
Pp: 488-499
Poliany G. Freitas*, Thiago C. Elias, Icaro A. Pinto, Luciano T. Costa, Paulo V.S.D. de Carvalho, Daniel de Q. Omote, Ihosvany Camps, Tati Ishikawa, Helen A. Arcuri, Susana Vinga, Arlindo L. Oliveira, Walter F.A. Junior and Nelson J.F. da Silveira
DOI: 10.2174/1570180814666170810120150

In Silico Bioactivity Prediction of Methoxime-3,4-dephostatin Derivatives on Human PTP1B: Search for Novel Antidiabetic Leads

Volume:15   Issue: 5
Pp: 500-507
Sabina B. Choudhury, Anupam D. Talukdar*, Manabendra D. Choudhury, Monjur A. Laskar and Abhishek Chowdhury
DOI: 10.2174/1570180814666170907162934

Antimicrobial Activity and Molecular Docking of Tannins from Pimenta dioica

Volume:15   Issue: 5
Pp: 508-515
Reham Al-Harbi, Mona Shaaban*, Razan Al-wegaisi, Fatma Moharram, Ola Abd El-Rahman and Shahenda El-Messery
DOI: 10.2174/1570180814666170810113850

A Comprehensive Review on Recent Developments in the Field of Biological Applications of Potent Pyrazolines Derived from Chalcone Precursors

Volume:15   Issue: 5
Pp: 516-574
Vinutha V. Salian, Badiadka Narayana*, Balladka K. Sarojini and Kullaiah Byrappa
DOI: 10.2174/1570180814666170703164221