Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 15 Issue: 5, May 2018

Design, Synthesis, Characterization and Antitubercular Screening of some New 1,2,4-Triazoles Derived from Isonicotinic Acid Hydrazides

Volume:15   Issue: 5
Pp: 451-462
Vaibhav Rajoriya, Varsha Kashaw* and Sushil K. Kashaw*
DOI: 10.2174/1570180814666170727143806
Published on: 27 July, 2017

Synthesis and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines of thieno[2,3-d]pyrimidine Derivatives Containing Isoxazole Moiety

Volume:15   Issue: 5
Pp: 463-474
Jianping Yong*, Canzhong Lu* and Xiaoyuan Wu
DOI: 10.2174/1570180814666170530093549
Published on: 29 May, 2017

Synthesis, Biological Evaluation, Molecular Docking Study and Acute Oral Toxicity Study of Coupled Imidazole-Pyrimidine Derivatives

Volume:15   Issue: 5
Pp: 475-487
Shailee V. Tiwari, Anna P.G. Nikalje*, Deepak K. Lokwani, Aniket P. Sarkate and Kizukala Jamir
DOI: 10.2174/1570180814666170704101817
Published on: 03 July, 2017

Computational Approach to the Discovery of Phytochemical Molecules with Therapeutic Potential Targets to the PKCZ protein

Volume:15   Issue: 5
Pp: 488-499
Poliany G. Freitas*, Thiago C. Elias, Icaro A. Pinto, Luciano T. Costa, Paulo V.S.D. de Carvalho, Daniel de Q. Omote, Ihosvany Camps, Tati Ishikawa, Helen A. Arcuri, Susana Vinga, Arlindo L. Oliveira, Walter F.A. Junior and Nelson J.F. da Silveira
DOI: 10.2174/1570180814666170810120150
Published on: 10 August, 2017

In Silico Bioactivity Prediction of Methoxime-3,4-dephostatin Derivatives on Human PTP1B: Search for Novel Antidiabetic Leads

Volume:15   Issue: 5
Pp: 500-507
Sabina B. Choudhury, Anupam D. Talukdar*, Manabendra D. Choudhury, Monjur A. Laskar and Abhishek Chowdhury
DOI: 10.2174/1570180814666170907162934
Published on: 07 September, 2017

Antimicrobial Activity and Molecular Docking of Tannins from Pimenta dioica

Volume:15   Issue: 5
Pp: 508-515
Reham Al-Harbi, Mona Shaaban*, Razan Al-wegaisi, Fatma Moharram, Ola Abd El-Rahman and Shahenda El-Messery
DOI: 10.2174/1570180814666170810113850
Published on: 09 August, 2017

A Comprehensive Review on Recent Developments in the Field of Biological Applications of Potent Pyrazolines Derived from Chalcone Precursors

Volume:15   Issue: 5
Pp: 516-574
Vinutha V. Salian, Badiadka Narayana*, Balladka K. Sarojini and Kullaiah Byrappa
DOI: 10.2174/1570180814666170703164221
Published on: 03 July, 2017