Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Personal Subscription
Become EABM
Become Reviewer



Meet Our Editorial Board Member free to download

Volume:15   Issue: 1
Pp: 1-1
Diego Dal Ben
DOI: 10.2174/157018081501180103102633



Preface free to download

Volume:15   Issue: 1
Pp: 2-2
George Perry
DOI: 10.2174/157018081501180103102945



QSAR Studies on NTF1836 Analogues as Mycothiol Biosynthesis Inhibitors

Volume:15   Issue: 1
Pp: 3-14
M.K. Kathiravan*, S.S. Nilewar and A.N. Kale
DOI: 10.2174/1570180814666170823163045




Synthesis and Herbicidal Evaluation of Aryloxyphenoxypropionate Derivatives Containing Purine Moiety

Volume:15   Issue: 1
Pp: 15-20
Jianjun Shi, Guihua Ren, Zhimeng Dai, Ningjie Wu, Jianquan Weng, Tianming Xu, Xinghai Liu* and Chengxia Tan*
DOI: 10.2174/1570180814666170505123102




New Oxadiazole Derivatives: Synthesis and Appraisal of Their Potential as Antimicrobial Agents

Volume:15   Issue: 1
Pp: 21-30
Deboleena Dhara, Dhanya Sunil*, Pooja R. Kamath, K. Ananda, S. Shrilakshmi and S. Balaji
DOI: 10.2174/1570180814666170425160545




Synthesis and Assessment of Novel Anti-chlamydial Benzylidene Acylhydrazides Derivatives

Volume:15   Issue: 1
Pp: 31-36
Xiaofeng Bao, Ying Xue, Chao Xia, Yin Lu, Ningjing Yang and Yu Zhao*
DOI: 10.2174/1570180814666170526170227




Design, Synthesis and Cytotoxic Activity of Spiro(oxindole-3-3'- pyrrolidine) Derivatives

Volume:15   Issue: 1
Pp: 37-45
Dilan Konyar*, Cenk A. Andac and Erdem Buyukbingol
DOI: 10.2174/1570180814666170810120634




Novel Azole-Functionalited Flouroquinolone Hybrids: Design, Conventional and Microwave Irradiated Synthesis, Evaluation as Antibacterial and Antioxidant Agents

Volume:15   Issue: 1
Pp: 46-64
Meltem Mentese, Neslihan Demirbas*, Arif Mermer, Serpil Demirci, Ahmet Demirbas and Faik Ahmet Ayaz
DOI: 10.2174/1570180814666170823163540




Design, Synthesis and Biological Evaluation of a Novel Series of Indole-3- Carboxamide Derivatives for Cancer Treatment as EGFR Inhibitors

Volume:15   Issue: 1
Pp: 70-83
Lan Zhang, Xin-Shan Deng, Guang-Peng Meng, Chao Zhang, Cong-Chong Liu, Gu-Zhou Chen , Xu-Liang Jiang*, Qing-Chun Zhao and Chun Hu*
DOI: 10.2174/1570180814666170929093258




Antiproliferative Effects of Nerium oleander Stem and Mitotic Ar rest Induced by Cardenolide Odoroside B on NCI-H460 Cancer Cells

Volume:15   Issue: 1
Pp: 84-94
Kehkashan Arshad Qamar*, Ahsana Dar Farooq, Bina S. Siddiqui, Nurul Kabir, Naseema Khatoon, Shakil Ahmed, Shaista Erum and Sabira Begum
DOI: 10.2174/1570180814666170727142145




Exploration of Angiotensin II Type 1 Receptor Modulators by Molecular Fingerprints and Docking Simulations

Volume:15   Issue: 1
Pp: 95-102
Sarfaraj Niazi*, Vishwamohana M. Hebbar, Pooja Mathew, Raj K.D. Kumar and Madhusudan Purohit*
DOI: 10.2174/1570180814666170605121418




Nalidixic Acid Schiff Bases: Synthesis and Biological Evaluation

Volume:15   Issue: 1
Pp: 103-111
Asif Husain, Munendra M. Varshney, Versha Parcha, Aftab Ahmad and Shah A. Khan*
DOI: 10.2174/1570180814666170710160751