Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:14   Issue: 7
Pp: 751-751
Kamil Kuca*
DOI: 10.2174/157018081407170630181923
Published on: 29 June, 2017



A Facile Synthesis and Drug Design of Some New Heterocyclic Compounds Incorporating Pyridine Moiety and Their Antimicrobial Evaluation

Volume:14   Issue: 7
Pp: 752-762
Fathy M. Abdelrazek, Sobhi M. Gomha*, Aly H. Abdelrahman, Peter Metz and Mohsen A. Sayed
DOI: 10.2174/1570180814666161128120240
Published on: 29 June, 2017




Novel Chromeno[2,3-d]pyrimidines-Design, Synthesis and Antioxidant Activity

Volume:14   Issue: 7
Pp: 763-772
Kotiah Yalagala, Sreekantha B. Jonnalagadda*, Suresh Maddila, Surjyakanta Rana and Surya Narayana Maddila
DOI: 10.2174/1570180814666161123143637
Published on: 29 June, 2017




Design, Synthesis, Antioxidant and Anticancer Activity of New Coumarin Derivatives Linked with Thiazole, Isoxazole or Pyrazole Moiety

Volume:14   Issue: 7
Pp: 773-781
Khaled R. A. Abdellatif*, Mohamed A. Abdelgawad, Heba A. H. Elshemy, Nesma M. Kahk and Dalia M. El Amir
DOI: 10.2174/1570180813666161026153743
Published on: 29 June, 2017




In vitro and In silico Analysis of β-lactam Derivatives as Antimycobacterial Agents

Volume:14   Issue: 7
Pp: 782-786
Julieta Luna-Herrera, Edgar E. Lara-Ramirez, Ana R. Munoz-Duarte, Fabian E. Olazaran, Manuel J. Chan-Bacab, Rosa Moo-Puc, Alondra M. Perez-Vazquez, Cynthia M. Morales-Reyes and Gildardo Rivera*
DOI: 10.2174/1570180814666170106111316
Published on: 29 June, 2017




Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorina ted Bioisosteres of Santacruzamate A as Potential HDAC Tracers

Volume:14   Issue: 7
Pp: 787-797
Muneer Ahamed, Koen Vermeulen, Michael Schnekenburger, Lise Roman Moltzau, Finn Olav Levy, Janos Marton, Mathy Froeyen, Dag Erlend Olberg, Marc Diederich and Guy Bormans
DOI: 10.2174/1570180813666161101152943
Published on: 29 June, 2017




3D-QSAR Studies of HDAC6 Inhibitors Using Docking-Based Alignment

Volume:14   Issue: 7
Pp: 798-810
Chunqi Hu, Liang Hong, Jun Li and Wenting Du*
DOI: 10.2174/1570180813666161028165151
Published on: 29 June, 2017




Inhibition of Product Template (PT) Domain of Aflatoxin Producing Polyketide Synthase Enzyme of Aspergillus parasiticus

Volume:14   Issue: 7
Pp: 811-818
Maneesh Kumar, Sindhuprava Rana, Harish Kumar, Jainendra Kumar, Rani Mansuri and Ganesh Chandra Sahoo*
DOI: 10.2174/1570180814666170203144914
Published on: 29 June, 2017




Tranylcypromine Attenuates Senescence in Dental Pulp Stem Cells

Volume:14   Issue: 7
Pp: 819-826
Junjun Liu, Zhi Liu, Chunyan Wang, Fang Yu, Wenping Cai, Xi Lu, Rongbin Wei, Shouliang Zhao, Yumei Zhao* and Shangfeng Liu*
DOI: 10.2174/1570180814666161229165048
Published on: 29 June, 2017




Nano Conjugated PLGA-Chlorambucil: Synthesis In Vitro Anti Non- Hodgkin's Lymphoma Cellular Assay

Volume:14   Issue: 7
Pp: 827-836
Saeed Akbarian, Jafar Sojoodi, Fatemeh Monnavari, Hossein Heidari, Pegah Khosravian, Hamid A. Javar, Artin Assadi, Rahimeh Rasouli, Mostafa Saffari, Seyed A.S. Shandiz, Hadi Hejazinia, Farnoor D. Omoomi, Mohammad Saffari and Mehdi S. Ardestani*
DOI: 10.2174/1570180814666161130113446
Published on: 29 June, 2017




Extended-release Formulation Attenuates the Impacts of Fluvastatin on Serum PCSK9 Levels in Humans

Volume:14   Issue: 7
Pp: 837-842
Yuan-Lin Guo, Wei Zhang, Qian Dong, Geng Liu, Cheng-Gang Zhu, Jing Sun, Rui-Xia Xu and Jian-Jun Li*
DOI: 10.2174/1570180814666161216121558
Published on: 29 June, 2017




Hydroxamate Inhibitor Profiling of Both Zn2+- and Ni2+-Activated Glyoxalase I Metalloenzymes Having Diverse Quaternary Structures

Volume:14   Issue: 7
Pp: 843-852
Uthaiwan Suttisansanee and John F. Honek*
DOI: 10.2174/1570180814666161128115808
Published on: 29 June, 2017




Polyphenolic Compound from Vitis vinifera L. have Potential for the Alzheimer Disease Treatment

Volume:14   Issue: 7
Pp: 853-859
Soukup Ondrej, Stralkova Radomira, Mistova Tereza, Popov Marek, Hejtmankova Alena, Lachman Jaromir, Klimova Blanka and Kuca Kamil*
DOI: 10.2174/1570180814666161116112300
Published on: 29 June, 2017