Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:14   Issue: 5
Pp: 507-507
Gyorgy Keglevich*
DOI: 10.2174/157018081405170406182644
Published on: 05 April, 2017



The Decisive Role of Mutual Arrangement of Hydroxy and Methoxy Groups in (3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8ahexahydro- 2H-chromene-4,8-diols in their Biological Activity

Volume:14   Issue: 5
Pp: 508-514
Alla Pavlova, Oksana Patrusheva, Irina Il`ina, Konstantin Volcho*, Tat`yana Tolstikova and Nariman Salakhutdinov
DOI: 10.2174/1570180813666161102142642
Published on: 05 April, 2017




Possible Binding Mode Analysis of Pyrazolo-triazole Hybrids as Potential Anticancer Agents through Validated Molecular Docking and 3D-QSAR Modeling Approaches

Volume:14   Issue: 5
Pp: 515-527
Siekh Abdul Amin, Nilanjan Adhikari, Ram K. Agrawal, Tarun Jha* and Shovanlal Gayen*
DOI: 10.2174/1570180813666160916153017
Published on: 05 April, 2017




Synthesis of Novel 4-(Dimethylaminoalkyl)piperazine-1-carbodithioa t e Derivatives as Cholinesterase Inhibitors

Volume:14   Issue: 5
Pp: 528-539
Ulviye Acar Cevik, Serkan Levent, Begum Nurpelin Saglık, Yusuf Ozkay* and Zafer Asım Kaplancıklı
DOI: 10.2174/1570180813666160923105636
Published on: 05 April, 2017




Synthesis, Docking and Antidiabetic Activity of Some Newer Benzamide Derivatives as Potential Glucokinase Activators

Volume:14   Issue: 5
Pp: 540-553
Rohit Singh, Viney Lather*, Deepti Pandita, Vikramjeet Judge, Karthikeyan N. Arumugam and Ajmer Singh Grewal
DOI: 10.2174/1570180813666160819125342
Published on: 05 April, 2017




Cytotoxic, Apoptotic and DNA Synthesis Inhibitory Effects of Some Thiazole Derivatives

Volume:14   Issue: 5
Pp: 554-566
Gulsen Akalın Ciftci, Mehlika Dilek Altıntop*, Halide Edip Temel, Ahmet Ozdemir and Zafer Asım Kaplancıklı
DOI: 10.2174/1570180813666160907170553
Published on: 05 April, 2017




Synthesis of Phosphorylated Derivatives of 2', 3'-O-Isopropylidene Adenosine and their In Ovo Antiviral Activity

Volume:14   Issue: 5
Pp: 567-572
Syed Rasheed, Chamarthi Naga Raju*, Golla Madhava, Chennamsetty Subramanyam, Shaik Thaslim Basha, Avilala Janardhan and Golla Narasimha
DOI: 10.2174/1570180813666161020112309
Published on: 05 April, 2017




Synthesis of Mannich Bases by Two Different Methods and Evaluation of their Acetylcholine Esterase and Carbonic Anhydrase Inhibitory Activities

Volume:14   Issue: 5
Pp: 573-580
Halise I. Gul*, Alkan Demirtas, Gokbay Ucar, Parham Taslimi and İlhami Gulcin
DOI: 10.2174/1570180814666161128120612
Published on: 05 April, 2017




Computational Analysis of Pyridopyrimidine-based Polo Like Kinase 2 (PLK2) Inhibitors: Examining the Structural Basis for Anticancer Activity

Volume:14   Issue: 5
Pp: 581-596
Anand Balupuri, Pavithra K. Balasubramanian and Seung Joo Cho*
DOI: 10.2174/1570180813666160831113237
Published on: 05 April, 2017




In Vivo Antimalarial and In Vitro Antileishmanial Activity of 4- Aminoquinoline Derivatives Hybridized to Isoniazid or Sulfa or Hydrazine Groups

Volume:14   Issue: 5
Pp: 597-604
Roberta R. Soares, Luciana M. R. Antinarelli, Isabela de O. Souza, Isabela de O. Souza, Fernanda V. Lopes, Kézia K. G. Scopel, Elaine S. Coimbra, Adilson D. da Silva and Clarice Abramo*
DOI: 10.2174/1570180813666160927113743
Published on: 05 April, 2017




Vitamin B12 Controlled Release with Crosslinked Poly (Acrylic Acid) and Poly (Methacrylic Acid) Based on Chitosan and Starch as pH Sensitive Hydrogels

Volume:14   Issue: 5
Pp: 605-612
Massomeh Ghorbanloo* and Somaieh Tarasi
DOI: 10.2174/1570180814666161118150532
Published on: 05 April, 2017




Quorum Sensing Inhibitor Activities of Celecoxib Derivatives in Pseudomonas aeruginosa

Volume:14   Issue: 5
Pp: 613-618
Seyhan Ulusoy, Sevil Senkardes, Inci Coskun, Gulgun Bosgelmez-Tınaz, Laurent Soulere, Yves Queneau and S. Guniz Kucukguzel*
DOI: 10.2174/1570180814666161121120719
Published on: 05 April, 2017




NF-κB Inhibitors in Head and Neck Cancer

Volume:14   Issue: 5
Pp: 619-633
Siddavaram Nagini*, Kranthi Kiran Kishore Tanagala and Indranil Chattopadhyay
DOI: 10.2174/1570180813666160926095002
Published on: 05 April, 2017