Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 13 Issue: 8, October 2016

Effect of Substituted Benzimidazoles and Somatostatin Analogs on the Vitality of Tumor Cell Lines and on the Oxidative Burst of Phagocytes

Volume:13   Issue: 8
Pp: 725-728
Ivan Goshev, Emilia Naydenova, Svetlana Staykova, Anelia Mavrova, Ljubomir Vezenkov and Diana Wesselinova
DOI: 10.2174/1570180813999160429112829
Published on: 28 April, 2016


Design, Synthesis and Biological Evaluation of Novel Tamibarotene Derivative as Multitarget Anticancer Agent

Volume:13   Issue: 8
Pp: 729-733
Yuqi Jiang, Jinning Hou, Xiaoyang Li, Wenfang Xu and Yingjie Zhang
DOI: 10.2174/157018081308160826182531
Published on: 26 August, 2016


Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

Volume:13   Issue: 8
Pp: 734-741
Kaan Kucukoglu, Halise Inci Gul, Mustafa Gul, Rengul Cetin-Atalay, Yosra Baratli and Bernard Geny
DOI: 10.2174/1570180813666160113002907
Published on: 12 January, 2016


Melanogenesis and Melanosome Transportation Modulators from Medicinal Plants

Volume:13   Issue: 8
Pp: 742-751
Kosei Yamauchi and Tohru Mitsunaga
DOI: 10.2174/157018081308160826183039
Published on: 26 August, 2016


Pharmacokinetics of Selegiline in a Rabbit Model

Volume:13   Issue: 8
Pp: 752-756
Huba Kalász, Kornélia Tekes, Zita Pöstényi, Eszter Vizvári, Péter Sótonyi, Dóra Szabó and Edit Tóth-Molnár
DOI: 10.2174/1570180813666160125224604
Published on: 25 January, 2016


QSAR and Molecular Modeling Studies on a Series of Indole-based Pyridone Analogues as HCV NS5B Polymerase Inhibitors

Volume:13   Issue: 8
Pp: 757-770
Neelu Singh, Basheerulla Shaik, Neeraj Agrawal, Anita K, Vijay K. Agrawal and Satya P. Gupta
DOI: 10.2174/1570180813666160815122359
Published on: 15 August, 2016


Effect of Hydrophilic Excipients on Cyclodextrin Complexes of Acyclovir in Improving Solubility, Dissolution and Permeability

Volume:13   Issue: 8
Pp: 771-780
Madhuri Maher, Mukesh Pandey, Lokesh Adhikari, Ajay Semalty and Mona Semalty
DOI: 10.2174/1570180813666160517161058
Published on: 17 May, 2016


Design and Evaluation of Microwave Induced Solid Dispersion of Tinidazole and Molecular Modelling with β-cyclodextrin

Volume:13   Issue: 8
Pp: 781-792
Swati Jagdale, Anish Kulkarni, Anuruddha Chabukswar and Bhanudas Kuchekar
DOI: 10.2174/1570180813999160429113650
Published on: 28 April, 2016


Synthesis and Biological Evaluation of New imidazo[1,2-a]pyridine Derivatives as Selective COX-2 Inhibitors

Volume:13   Issue: 8
Pp: 793-799
Mahsa Azami Movahed, Bahram Daraei and Afshin Zarghi
DOI: 10.2174/1570180813666160613090944
Published on: 12 June, 2016


Synthesis and Evaluation of Anticonvulsant Activities of Pyrazol yl Semicarbazones. Part II

Volume:13   Issue: 8
Pp: 800-808
Ming-Xia Song, Yi Wu and Xian-Qing Deng
DOI: 10.2174/1570180813666160711155752
Published on: 11 July, 2016


Design, Synthesis and Bioactivity Evaluation of Novel Dabigatran Derivatives as Potential Thrombin Inhibitors

Volume:13   Issue: 8
Pp: 809-817
Qianqian Liu, Yujie Ren and Xiaodong Gao
DOI: 10.2174/1570180813666160622081105
Published on: 21 June, 2016


Synthesis and Anticonvulsant Activity of Novel 3-(2-(4H-1,2,4-triazol-4- yl)ethyl)-1-alkyl-1H-indole Derivatives

Volume:13   Issue: 8
Pp: 833-839
Chuan-Feng Liu, Hong-Jian Zhang and Zhe-Shan Quan
DOI: 10.2174/1570180813666160324173717
Published on: 24 March, 2016


In silico Modeling Studies of 5-HT2B Antagonistic Activity of 2-(2- phenylethyl)chromone Derivatives from Cucumis melo Seeds

Volume:13   Issue: 8
Pp: 840-844
Sabrin R. M. Ibrahim, Gamal A. Mohamed and Shahenda M. El-Messery
DOI: 10.2174/1570180813666160517164432
Published on: 17 May, 2016