Letters in Drug Design & Discovery


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Effect of Substituted Benzimidazoles and Somatostatin Analogs on the Vitality of Tumor Cell Lines and on the Oxidative Burst of Phagocytes

Volume:13   Issue: 8
Pp: 725-728
Ivan Goshev, Emilia Naydenova, Svetlana Staykova, Anelia Mavrova, Ljubomir Vezenkov and Diana Wesselinova
DOI: 10.2174/1570180813999160429112829

Design, Synthesis and Biological Evaluation of Novel Tamibarotene Derivative as Multitarget Anticancer Agent

Volume:13   Issue: 8
Pp: 729-733
Yuqi Jiang, Jinning Hou, Xiaoyang Li, Wenfang Xu and Yingjie Zhang
DOI: 10.2174/157018081308160826182531

Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

Volume:13   Issue: 8
Pp: 734-741
Kaan Kucukoglu, Halise Inci Gul, Mustafa Gul, Rengul Cetin-Atalay, Yosra Baratli and Bernard Geny
DOI: 10.2174/1570180813666160113002907

Melanogenesis and Melanosome Transportation Modulators from Medicinal Plants

Volume:13   Issue: 8
Pp: 742-751
Kosei Yamauchi and Tohru Mitsunaga
DOI: 10.2174/157018081308160826183039

Pharmacokinetics of Selegiline in a Rabbit Model

Volume:13   Issue: 8
Pp: 752-756
Huba Kalász, Kornélia Tekes, Zita Pöstényi, Eszter Vizvári, Péter Sótonyi, Dóra Szabó and Edit Tóth-Molnár
DOI: 10.2174/1570180813666160125224604

QSAR and Molecular Modeling Studies on a Series of Indole-based Pyridone Analogues as HCV NS5B Polymerase Inhibitors

Volume:13   Issue: 8
Pp: 757-770
Neelu Singh, Basheerulla Shaik, Neeraj Agrawal, Anita K, Vijay K. Agrawal and Satya P. Gupta
DOI: 10.2174/1570180813666160815122359

Effect of Hydrophilic Excipients on Cyclodextrin Complexes of Acyclovir in Improving Solubility, Dissolution and Permeability

Volume:13   Issue: 8
Pp: 771-780
Madhuri Maher, Mukesh Pandey, Lokesh Adhikari, Ajay Semalty and Mona Semalty
DOI: 10.2174/1570180813666160517161058

Design and Evaluation of Microwave Induced Solid Dispersion of Tinidazole and Molecular Modelling with β-cyclodextrin

Volume:13   Issue: 8
Pp: 781-792
Swati Jagdale, Anish Kulkarni, Anuruddha Chabukswar and Bhanudas Kuchekar
DOI: 10.2174/1570180813999160429113650

Synthesis and Biological Evaluation of New imidazo[1,2-a]pyridine Derivatives as Selective COX-2 Inhibitors

Volume:13   Issue: 8
Pp: 793-799
Mahsa Azami Movahed, Bahram Daraei and Afshin Zarghi
DOI: 10.2174/1570180813666160613090944

In silico Modeling Studies of 5-HT2B Antagonistic Activity of 2-(2- phenylethyl)chromone Derivatives from Cucumis melo Seeds

Volume:13   Issue: 8
Pp: 840-844
Sabrin R. M. Ibrahim, Gamal A. Mohamed and Shahenda M. El-Messery
DOI: 10.2174/1570180813666160517164432