Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Efficient Synthesis of Pamidronic Acid Using an Ionic Liquid Additive open access plus

Volume:13   Issue: 6
Pp: 475-478
Alajos Grun, Dávid Illés Nagy, Sándor Garadnay, István Greiner and Gyorgy Keglevich
DOI: 10.2174/1570180812666151022221805
Published on: 17 June, 2016


Synthesis and Biological Evaluation of Some New Indolizine Derivatives as Antitumoral Agents

Volume:13   Issue: 6
Pp: 479-488
Liliana Lucescu, Elena Bîcu, Dalila Belei, Joelle Dubois and Alina Ghinet
DOI: 10.2174/1570180812666151022221628
Published on: 17 June, 2016


Synthesis and Biological Evaluation of Macamides Derivatives as Potent Inhibitors of Breast Cancer Cell MCF-7

Volume:13   Issue: 6
Pp: 489-494
Xiao Xia Liang, Cheng Xiong, Min He, Changliang He and Zhongqiong Yin
DOI: 10.2174/1570180813888160201100814
Published on: 17 June, 2016


Formamide Derivatives of Resveratrol: Synthesis, Characterization and Cytotoxicity

Volume:13   Issue: 6
Pp: 495-504
Hai-Jun Ni, Hui-Jie Cheng, Wei-Wei Ge, Meng-Xue Lin, Qing-Shan Li and Ban-Feng Ruan
DOI: 10.2174/157018081306160618153304
Published on: 17 June, 2016


Synthesis and Microbial Evaluation of Versatile Base Catalyzed Chiral Tetrahydrobenzofuran Derivatives via Multicomponent Reaction

Volume:13   Issue: 6
Pp: 505-513
Khushal Kapadiya, Rohit Kotadiya, Kishor Kavadia, Ramesh Kothari, Krunal Mehariya and Ranjan Khunt
DOI: 10.2174/1570180812666150914220727
Published on: 17 June, 2016


QSPR Model for Dispersibility of Graphene in Various Solvents

Volume:13   Issue: 6
Pp: 514-520
Alla P. Toropova and Andrey A. Toropov
DOI: 10.2174/1570180812666151022221942
Published on: 17 June, 2016


Microwave Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-triazolo[4,3-a] pyridine Moiety

Volume:13   Issue: 6
Pp: 521-525
Zhi-Wen Zhai, Yan-Xia Shi, Ming-Yan Yang, Wen Zhao, Zhao-Hui Sun, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang
DOI: 10.2174/157018081306160618181757
Published on: 17 June, 2016


In silico Studies Toward the Discovery of Novel Type-II Inhibitors of TrkA: Pharmacophore-based 3D-QSAR Modeling, Database Screening and Molecular Docking

Volume:13   Issue: 6
Pp: 526-538
Yahui Tian, Lu Zhou, Xiaoli Li, Suwen Zhou, Rong Yong and Liangliang Zhong
DOI: 10.2174/1570180812666151013205048
Published on: 17 June, 2016


Progress on the Discovery of Inhibitors of InhA, the FAS II Enoyl-ACP Reductase TB Drug Discovery Targeted on InhA

Volume:13   Issue: 6
Pp: 539-546
Yi Zhang, Longxiang Xie and Jianping Xie
DOI: 10.2174/1570180812666151016205422
Published on: 17 June, 2016


Synthesis & Characterization of 2-(substituted-phenyl)acetohydrazide Analogs, 1,3,4-oxadiazoles, and 1,2,4-triazine Ring Systems: A Novel Class of Potential Analgesic and Anti-Inflammatory Agents

Volume:13   Issue: 6
Pp: 547-562
Prakash S. Nayak, Badiadka Narayana, Jennifer Fernandes, Balladka K. Sarojini, Sana Sheik, Kenkere S. Shashidhara, Konambi R. Chandrashekhar and Kullaiah Byrappa
DOI: 10.2174/1570180812666151003001957
Published on: 17 June, 2016


Synthesis and Antiproliferative Activity of 2-arylidene 6-(2-aryl-2-oxoethoxy)Benzofuran-3-one Derivatives

Volume:13   Issue: 6
Pp: 563-569
Seref Demirayak, Leyla Yurttas, Ahmet Cagri Karaburun, Nalan Gundogdu-Karaburun and Ismail Kayagil
DOI: 10.2174/1570180813999160429113316
Published on: 17 June, 2016


Synthesis, Anti-cancer Activity and Mechanism Study of 6-Mercapto-purine Derivatives

Volume:13   Issue: 6
Pp: 570-576
Yu-qin Ma, Xing Yan, Rong Du, Xiao-guang Yang, Yu-xin Li, Ying Gao and Wen-liang Li
DOI: 10.2174/1570180812666150821003536
Published on: 17 June, 2016