Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Antipsychotics as Psychosis Drugs and Neuroprotective Promoters Evaluated by Chemical QSAR - in silico and in vivo Studies

Volume:13   Issue: 4
Pp: 269-275
Maria Mernea, Livia-Cristina Borcan, Florin Borcan and Speranta Avram
DOI: 10.2174/1570180812666150924000107
Published on: 03 March, 2016


Comparative Study of the Inhibition of E. coli and Murine Aspartate Transcarbamylase by Phenobarbital Analogues

Volume:13   Issue: 4
Pp: 276-281
Mahmoud Balbaa, Razan Hammoud and Hoda Yusef
DOI: 10.2174/1570180812666150818235237
Published on: 03 March, 2016


Study of Binding Epitopes by STD-NMR Spectroscopy and Molecular Docking of Urease Inhibitors from Lichens

Volume:13   Issue: 4
Pp: 282-294
Vinitha Moolchand Thadhani, Ajmal Khan, Atia-tul-Wahab, Sumaira Javaid, Amsal Shafqat, Zaheer-ul-Haq and M. Iqbal Choudhary
DOI: 10.2174/1570180812666150907204007
Published on: 03 March, 2016


Design of Novel Biphenyl-2-thioxothiazolidin-4-one Derivatives as Potential Protein Tyrosine Phosphatase (PTP)-1B Inhibitors Using Molecular Docking Study

Volume:13   Issue: 4
Pp: 295-300
Sant Kumar Verma, Tarun Rajpoot, Manoj K. Gautam, Akhlesh K. Jain and Suresh Thareja
DOI: 10.2174/1570180812666150819002954
Published on: 03 March, 2016


Structural Insight of NICD-MAML Interactions: Virtual Screening, Docking and Molecular Dynamics Study for Identification of Potential Inhibitor

Volume:13   Issue: 4
Pp: 301-313
Noopur Sinha, Saikat Chowdhury and Ram Rup Sarkar
DOI: 10.2174/1570180812666150819003634
Published on: 03 March, 2016


Design, Synthesis and Biological Evaluation of Salicylamide Analogues as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Volume:13   Issue: 4
Pp: 314-323
Yang Liu, Yijing Li, Jianzhen Liu, Limin Yang, Pengzhan Li and Guisen Zhao
DOI: 10.2174/1570180812666150819003111
Published on: 03 March, 2016


Microwave Assisted Synthesis and Antifungal Activity of Some Novel Hydrazones Containing Pyridine Moiety

Volume:13   Issue: 4
Pp: 324-328
Li-Jing Min, Yan-Xia Shi, Ming-Yan Yang, Zhi-Wen Zhai, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang
DOI: 10.2174/1570180812666151003002140
Published on: 03 March, 2016


Synthesis and Antitumor Activity of Novel N-Benzoyl-N'-substituted Pyrimidinyl (Thio)semicarbazide Derivatives

Volume:13   Issue: 4
Pp: 329-334
Gaopeng Song, Jianzuo Li, Hao Tian, Yasheng Li, Dekun Hu, Ying Li and Zining Cui
DOI: 10.2174/1570180812666151003002644
Published on: 03 March, 2016


Synthesis of Novel C3-Linked β-Carboline-Pyridine Derivatives Employing Khronke Reaction: DNA-binding Ability and Molecular Modeling Studies

Volume:13   Issue: 4
Pp: 335-342
Nagula Shankaraiah, Pankaj Sharma, Srinivas Pedapati, Shalini Nekkanti, Vunnam Srinivasulu, Niggula Praveen Kumar and Ahmed Kamal
DOI: 10.2174/157018081304160303180050
Published on: 03 March, 2016


Synthesis and Biological Activity of Novel N-glucosides Containing Substituted Piperazine Moiety

Volume:13   Issue: 4
Pp: 343-351
Li-Yuan Zhang, Bao-Lei Wang, Yi-Zhou Zhan, Xue-Wen Hua, Ming Liu, Xiao Zhang, Hai-Bin Song and Zheng-Ming Li
DOI: 10.2174/1570180812666150819003514
Published on: 03 March, 2016