Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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β-Galactosidase – Excipients Interaction by Docking Simulation Studies

Volume:13   Issue: 10
Pp: 993-998
Larissa L. Rodrigues, Alexandre C. Bertoli, Ihosvany Camps, Marcello G. Trevisan and Jerusa S. Garcia
DOI: 10.2174/1570180813666160628075149




Analysis of the Applicability and Use of Lipinski`s Rule for Central Nervous System Drugs

Volume:13   Issue: 10
Pp: 999-1006
Thais B. Fernandes, Mariana C. F. Segretti, Michelle C. Polli and Roberto Parise-Filho
DOI: 10.2174/1570180813666160622092839




Principles of an Adenovirus-Based Assay for Candidate Compounds with Broad Spectrum of Anti-Neoplastic Activities

Volume:13   Issue: 10
Pp: 1007-1011
Mikhail V. Shepelev, Elena V. Korobko and Igor V. Korobko
DOI: 10.2174/1570180813666160422162612




Structure-based Virtual Screening to Get New Scaffold Inhibitors of the Ser/Thr Protein Kinase PknB from Mycobacterium tuberculosis

Volume:13   Issue: 10
Pp: 1012-1018
Antonio Coluccia, Giuseppe La Regina, Nathalie Barilone, María-Natalia Lisa, Andrea Brancale, Gwenaëlle André-Leroux, Pedro M. Alzari and Romano Silvestri
DOI: 10.2174/1570180813666160801162204




Synthesis and Antiviral Activity of 2-aryl-4H-chromen-4-one Derivatives Against Chikungunya Virus

Volume:13   Issue: 10
Pp: 1019-1024
Vishnu N. Badavath, Surender S. Jadav, Boris Pastorino, Xavier de Lamballerie, Barij N. Sinha and Venkatesan Jayaprakash
DOI: 10.2174/1570180813666160711163349




Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase: Design, Synthesis and Evaluation

Volume:13   Issue: 10
Pp: 1025-1032
Haojun Gong, Lu Zhou, Deyong Ye, Xing Gao, Yali Li, Xiangyu Qi and Yong Chu
DOI: 10.2174/1570180813666160805155116




Exploring the QSAR Analysis of imidazole-4, 5- and pyrazine-2,3- Dicarboxamides Derivatives Using Online Available Resources

Volume:13   Issue: 10
Pp: 1047-1054
Arpit K. Gupta, Ravi Raushan, Jagadish Singh and Partha P. Roy
DOI: 10.2174/1570180813666160714144725




Topomer CoMFA 3D-QSAR and Docking Studies of Pyrimidine Inhibitors of Pneumocystis Carinii Dihydrofolate Reductase

Volume:13   Issue: 10
Pp: 1055-1062
Jianbo Tong, Pei Zhan, Tuanli Yao, Lanbing Ma and Min Bai
DOI: 10.2174/1570180813666160324154549




Synthesis and Antimicrobial Evaluation of Aminoguanidine and 3-amino- 1,2,4-triazole Derivatives as Potential Antibacterial Agents

Volume:13   Issue: 10
Pp: 1063-1075
Tian-Yi Zhang, Chao Li, Ya-Ru Li, Xiao-Zhen Li, Liang-Peng Sun, Chang-Ji Zheng and Hu-Ri Piao
DOI: 10.2174/1570180813666160819151239




Microwave Assisted Synthesis and Antimicrobial Activity Evaluation of New Heterofunctionalized Norfloxacine Derivatives

Volume:13   Issue: 10
Pp: 1076-1090
Meltem Mentese, Serpil Demirci, Serap B. Ozdemir, Ahmet Demirbas, Serdar Ulker and Neslihan Demirbas
DOI: 10.2174/1570180813666160712222922




Facile Synthesis and Nitric Oxide Inhibitory Activity of Aurones, Rugaurone A, Gramflavonoid A and Their Derivatives

Volume:13   Issue: 10
Pp: 1091-1098
Kongara Damodar, Jin-Kyung Kim and Jong-Gab Jun
DOI: 10.2174/1570180813666160824124224




Preparation of Edible Zein Hybrid Particles and Its Controlled Release Behaviors

Volume:13   Issue: 10
Pp: 1099-1103
Siyao Lv, Jie Liu, Fei Pei, Yufeng He and Rong-Min Wang
DOI: 10.2174/1570180813666160720122349




ACKNOWLEDGEMENTS TO REVIEWERS free to download

Volume:13   Issue: 10
Pp: 1104-1104

DOI: 10.2174/157018081310161101000734