Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 13 Issue: 1, January 2015

Meet Our Editorial Board Member: free to download

Volume:13   Issue: 1
Pp: 1-1
Dimitra Hadjipavlou-Litina
DOI: 10.2174/157018081301151030152444
Published on: 30 October, 2015

Preface: free to download

Volume:13   Issue: 1
Pp: 2-2
DOI: 10.2174/157018081301151030152607
Published on: 30 October, 2015

Evaluation of Serine Protease Inhibitors as Potent FVIIa-sTF Inhibitors in the Blood Coagulation Cascade

Volume:13   Issue: 1
Pp: 3-23
Andrea Roxanne J. Anas and Ken-ichi Harada
DOI: 10.2174/1570180812666150608230214
Published on: 08 June, 2015

Development of Energy-based Pharmacophore Model and Stepwise Virtual Screening of LRRK2 Inhibitors Through Molecular Dynamics and Mechanics

Volume:13   Issue: 1
Pp: 24-32
Sagar S. Bhayye, Kunal Roy and Achintya Saha
DOI: 10.2174/1570180812666150611185331
Published on: 11 June, 2015

Studies on the IC50 of Trisubstituted Thiazoles as Cdc7 Kinase Inhibitors

Volume:13   Issue: 1
Pp: 33-42
Huazhen Yang, Xun Liu, Zhiling Ye, Fucheng Song, Lianhua Cui, Zhuang Yu, Hongzong Si and Honglin Zhai
DOI: 10.2174/1570180812999150713144215
Published on: 13 July, 2015

Molecular Simulation of HDAC1/3 Inhibitor: Insights into the Structural Basis of Selectivity

Volume:13   Issue: 1
Pp: 43-46
Lei Zhang and Lihui Zhang
DOI: 10.2174/1570180812666150630183816
Published on: 30 June, 2015

Recent Developments in the Synthesis and Applications of Anticancer Amonafide Derivatives. A Mini Review

Volume:13   Issue: 1
Pp: 47-63
Gary Gellerman
DOI: 10.2174/1570180812666150529205049
Published on: 29 May, 2015

A Series of 2,4(1H,3H)-Quinazolinedione Derivatives: Synthesis and Biological Evaluation as Potential Anticancer Agents

Volume:13   Issue: 1
Pp: 64-76
Hulya Akgun, Demet Us Yilmaz, Rengul Cetin Atalay and Damla Gozen
DOI: 10.2174/1570180812666150529204909
Published on: 29 May, 2015

Synthesis, Biological Evaluation and Molecular Docking Studies of 4Hbenzo[ h]chromenes, 7H-benzo[h]chromeno[2,3-d]pyrimidines as Antitumor Agents

Volume:13   Issue: 1
Pp: 77-88
Ahmed H. Halawa, Ahmed M. Fouda, Al-Anood M. Al-Dies and Ahmed M. El-Agrody
DOI: 10.2174/1570180812666150611185830
Published on: 11 June, 2015

Design, Synthesis and Biological Evaluation of 4-(Imidazolylmethyl)-2- Aryl-Quinoline Derivatives as Aromatase Inhibitors and Anti-breast Cancer Agents

Volume:13   Issue: 1
Pp: 89-97
Razieh Ghodsi, Ebrahim Azizi, Maria Grazia Ferlin, Vincenzo Pezzi and Afshin Zarghi
DOI: 10.2174/1570180812666150611185605
Published on: 11 June, 2015

Novel Aminopeptidase N Inhibitors with Improved Antitumor Activities

Volume:13   Issue: 1
Pp: 98-106
Qiang Wang, Qiao Shi and Lu Huang
DOI: 10.2174/1570180812666150611190608
Published on: 11 June, 2015

Biological Properties of Heterocyclic Pyridinylimines and Pyridinylhydrazones

Volume:13   Issue: 1
Pp: 107-114
Francislene J. Martins, Rebeca Mol Lima, Juliana Alves dos Santos, Patricia de Almeida Machado, Elaine Soares Coimbra, Adilson David da Silva and Nádia Rezende Barbosa Raposo
DOI: 10.2174/1570180812666141216205601
Published on: 16 December, 2014