Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Meet Our Editorial Board Member: free to download

Volume:13   Issue: 1
Pp: 1-1
Dimitra Hadjipavlou-Litina
DOI: 10.2174/157018081301151030152444



Preface: free to download

Volume:13   Issue: 1
Pp: 2-2
Atta-ur-Rahman
DOI: 10.2174/157018081301151030152607

Evaluation of Serine Protease Inhibitors as Potent FVIIa-sTF Inhibitors in the Blood Coagulation Cascade promotion: free to download

Volume:13   Issue: 1
Pp: 3-23
Andrea Roxanne J. Anas and Ken-ichi Harada
DOI: 10.2174/1570180812666150608230214


Development of Energy-based Pharmacophore Model and Stepwise Virtual Screening of LRRK2 Inhibitors Through Molecular Dynamics and Mechanics promotion: free to download

Volume:13   Issue: 1
Pp: 24-32
Sagar S. Bhayye, Kunal Roy and Achintya Saha
DOI: 10.2174/1570180812666150611185331


Studies on the IC50 of Trisubstituted Thiazoles as Cdc7 Kinase Inhibitors promotion: free to download

Volume:13   Issue: 1
Pp: 33-42
Huazhen Yang, Xun Liu, Zhiling Ye, Fucheng Song, Lianhua Cui, Zhuang Yu, Hongzong Si and Honglin Zhai
DOI: 10.2174/1570180812999150713144215


Molecular Simulation of HDAC1/3 Inhibitor: Insights into the Structural Basis of Selectivity promotion: free to download

Volume:13   Issue: 1
Pp: 43-46
Lei Zhang and Lihui Zhang
DOI: 10.2174/1570180812666150630183816


Recent Developments in the Synthesis and Applications of Anticancer Amonafide Derivatives. A Mini Review promotion: free to download

Volume:13   Issue: 1
Pp: 47-63
Gary Gellerman
DOI: 10.2174/1570180812666150529205049


A Series of 2,4(1H,3H)-Quinazolinedione Derivatives: Synthesis and Biological Evaluation as Potential Anticancer Agents promotion: free to download

Volume:13   Issue: 1
Pp: 64-76
Hulya Akgun, Demet Us Yilmaz, Rengul Cetin Atalay and Damla Gozen
DOI: 10.2174/1570180812666150529204909


Synthesis, Biological Evaluation and Molecular Docking Studies of 4Hbenzo[ h]chromenes, 7H-benzo[h]chromeno[2,3-d]pyrimidines as Antitumor Agents promotion: free to download

Volume:13   Issue: 1
Pp: 77-88
Ahmed H. Halawa, Ahmed M. Fouda, Al-Anood M. Al-Dies and Ahmed M. El-Agrody
DOI: 10.2174/1570180812666150611185830


Design, Synthesis and Biological Evaluation of 4-(Imidazolylmethyl)-2- Aryl-Quinoline Derivatives as Aromatase Inhibitors and Anti-breast Cancer Agents promotion: free to download

Volume:13   Issue: 1
Pp: 89-97
Razieh Ghodsi, Ebrahim Azizi, Maria Grazia Ferlin, Vincenzo Pezzi and Afshin Zarghi
DOI: 10.2174/1570180812666150611185605


Novel Aminopeptidase N Inhibitors with Improved Antitumor Activities promotion: free to download

Volume:13   Issue: 1
Pp: 98-106
Qiang Wang, Qiao Shi and Lu Huang
DOI: 10.2174/1570180812666150611190608


Biological Properties of Heterocyclic Pyridinylimines and Pyridinylhydrazones promotion: free to download

Volume:13   Issue: 1
Pp: 107-114
Francislene J. Martins, Rebeca Mol Lima, Juliana Alves dos Santos, Patricia de Almeida Machado, Elaine Soares Coimbra, Adilson David da Silva and Nádia Rezende Barbosa Raposo
DOI: 10.2174/1570180812666141216205601