Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Personal Subscription
Become EABM
Become Reviewer
Call for Editor

Meet Our Editor promotion: free to download

Volume:12   Issue: 6
Pp: 447-447
Atta -ur- Rahman
DOI: 10.2174/157018081206150507143626
Published on: 06 May, 2015

First Efficient Two-Step/One-Pot Zirconium (IV)isopropoxide–Mediated Reductive Amination of Carbonyl Compounds

Volume:12   Issue: 6
Pp: 448-456
Cyril Pieri and Jean Michel Brunel
DOI: 10.2174/1570180812666141215215120
Published on: 06 May, 2015


FeCl3/Ultrasound Mediated Reaction of 2-aminothiophenol with Aldehydes in Water: Synthesis of 2-substituted Benzothiazoles of Pharmacological Interest

Volume:12   Issue: 6
Pp: 457-465
Ponasanapalli Tirumala Venkata Ankayya Srinivas, Sallagundla Bhavani, Dandela Rambabu, Mandava Venkata Basaveswara Rao, Ravikumar Kapavarapu and Manojit Pal
DOI: 10.2174/1570180812666141216211045
Published on: 06 May, 2015


Synthesis of Six Phenylalanine Derivatives and their Cell Toxicity Effect on Human Colon Cancer Cell Line HT-29

Volume:12   Issue: 6
Pp: 466-470
Qianyi Zhao, Ting Xu, Menghua Li, Ying Yang, Haopeng Hu, Shupei Wang, Wenjuan Yan, Ran Chen, Chunyan Zhang and Cunshuan Xu
DOI: 10.2174/1570180812666141206001604
Published on: 06 May, 2015

Synthesis and Antitumor Activity of New Pyrimidine and Caffeine Derivatives

Volume:12   Issue: 6
Pp: 471-478
Ameen Ali Abu-Hashem and Hoda Abdel Raouf Hussein
DOI: 10.2174/1570180812666150429234237
Published on: 06 May, 2015


De Novo Design of High Potent DPP-IV Inhibitors Based on the Scaffold of Cyanopyrrolidine

Volume:12   Issue: 6
Pp: 479-487
Yu-Lei Jiang, Hao-Liang Yuan, Wei-Wei Zhang, Hai-Chun Liu, Yan-Min Zhang, Xiao Xiong, Jin-Xing Xu, Shuai Lu, Tao Lu and Ya-Dong Chen
DOI: 10.2174/1570180812666141201223016
Published on: 06 May, 2015


Biological Evaluation of Halogenated Thioureas as Cholinesterases Inhibitors Against Alzheimer’s Disease & Molecular Modeling Studies

Volume:12   Issue: 6
Pp: 488-494
Jamshed Iqbal, Sumera Zaib, Aamer Saeed and Muhammad Muddassar
DOI: 10.2174/1570180812666141201222247
Published on: 06 May, 2015


Novel Fatty Acid Analogues as Human Fatty Acid Synthase Thioesterase Domain Inhibitors: Synthesis and their Cytotoxicity Screening

Volume:12   Issue: 6
Pp: 495-499
Selvaraj Jubie, Pawan Kumar Yadhav, Moola Joghee Nanjan Chandrasekar, Jeyapal Gomathi Priya, Chaitanya MVNL and Palanisamy Dhanabal
DOI: 10.2174/1570180812666141216210751
Published on: 06 May, 2015


Synthesis, Characterization and Microbial Activity of new Aryl esters of 1,1'-bis(4-hydroxyphenyl)cyclohexane

Volume:12   Issue: 6
Pp: 505-511
Chirag Bhupendra Patel, Bhavin Babu Dhaduk and Parsotam Hari Parsania
DOI: 10.2174/1570180812666141224211602
Published on: 06 May, 2015


Preparation and Characterization of CS/(β-CD)/PAA Composite Hydrogels for Controlled Drug Delivery

Volume:12   Issue: 6
Pp: 512-517
Jie Ren, Xiaoci Yang, Mengqi Yao, Jinfen Gu, Xiaohua Tang and W u Yang
DOI: 10.2174/1570180812666150224231250
Published on: 06 May, 2015