Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 11 Issue: 4, May 2014

Graphical Abstracts

Volume:11   Issue: 4
Pp: i-vii

DOI: 10.2174/157018081104140311111852
Published on: 11 March, 2014

In Vitro Antitumoral Activity of Palladium(II) and Platinum(II) Complexes with O,O'-Dialkyl Esters of Ethylene-bis(S)-Leucine

Volume:11   Issue: 4
Pp: 387-394
Jelena M. Vujic, Goran N. Kaluderovic, Tatjana P. Stanojkovic, Jadranka A. Antic and Srecko R. Trifunovic
DOI: 10.2174/15701808113106660092
Published on: 21 October, 2013


Synthesis and Antitumor Invasive Activity of Novel Ionone Alkaloid Derivatives

Volume:11   Issue: 4
Pp: 395-402
Hai-Jun Fang, Qian Liu, Chun-Chun Gan, Mei-Na Jin, Nan Qin and Hong-Quan Duan
DOI: 10.2174/15701808113106660094
Published on: 22 October, 2013


Toward the Identification of Novel Carbonic Anhydrase XIV Inhibitors using 3D-QSAR Pharmacophore Model, Virtual Screening and Molecular Docking Study

Volume:11   Issue: 4
Pp: 403-412
Tao Liu, Lu Zhou, Taijin Wang, Lufen He and Xiangyang Tang
DOI: 10.2174/15701808113106660083
Published on: 30 September, 2013


Synthesis of 2,5-Disubstituted-1,3,4-oxadiazole Analogs as Novel Anticancer and Antimicrobial Agents

Volume:11   Issue: 4
Pp: 413-419
Mohamed Jawed Ahsan, Jyotika Sharma, Sandeep Bhatia, Pramod Kumar Goyal, Kailash Shankhala and Mukand Didel
DOI: 10.2174/1570180810666131113211647
Published on: 13 November, 2013


QSAR Study of H1N1 Neuraminidase Inhibitors from Influenza a Virus

Volume:11   Issue: 4
Pp: 420-427
Apilak Worachartcheewan, Chanin Nantasenamat, Chartchalerm Isarankura-Na-Ayudhya and Virapong Prachayasittikul
DOI: 10.2174/15701808113106660085
Published on: 07 October, 2013


In-Vitro Antiproliferative Activity of New Tetrahydroisoquinolines (THIQs) on Ishikawa Cells and their 3D Pharmacophore Models

Volume:11   Issue: 4
Pp: 428-436
Suresh Kumar V. K. Eyunni, Madhavi Gangapuram and Kinfe K. Redda
DOI: 10.2174/1570180811666131203002502
Published on: 02 December, 2013


Design and Synthesis of Novel 2- Substituted Benzothiazole Compounds as PTP1B Inhibitors

Volume:11   Issue: 4
Pp: 444-453
Arun P. Chandrasekharappa, Sangamesh E. Badiger, Pramod K. Dubey, Sunil K. Panigrahi and Sekhar Reddy VVV. Manukonda
DOI: 10.2174/15701808113106660076
Published on: 17 September, 2013


Synthesis, Molecular Docking and In Vitro Antimicrobial Studies of Novel Pyrazole Analogues of Curcumin

Volume:11   Issue: 4
Pp: 474-483
Dileep Kumar, Harish B. G., Mayank Gangwar, Manish Kumar, Dharmendra Kumar, Ragini Tilak, Gopal Nath, Ashok Kumar and Sushil Kumar Singh
DOI: 10.2174/15701808113106660087
Published on: 07 October, 2013


Improved Synthesis of Antiviral Drug Valacyclovir Hydrochloride

Volume:11   Issue: 4
Pp: 484-487
Keshava Navin Kumar Reddy, Murugulla Adharvana Chari, Mayur. D. Khunt, B. Ramachandra Reddy, Vurimidi Himabindu and Ghanta Mahesh Reddy
DOI: 10.2174/15701808113106660090
Published on: 21 October, 2013


Synthesis and Evaluation of Anticonvulsant Activities of Triazole- Incorporated Benzothiazoles

Volume:11   Issue: 4
Pp: 488-494
Ming-Xia Song, Hong Zeng, Xian-Qing Deng and Zhe-Shan Quan
DOI: 10.2174/15701808113106660093
Published on: 22 October, 2013


Improvement of Generic Sevoflurane by a New Production Process

Volume:11   Issue: 4
Pp: 495-501
Tomo Hayase, Shigekazu Sugino, Shun-suke Tachibana, Naoyuki Hirata and Michiaki Yamakage
DOI: 10.2174/1570180810666131113211447
Published on: 13 November, 2013


The Study of the Biological Activity of Amino-Substituted Benzofuroxans

Volume:11   Issue: 4
Pp: 502-512
Elena A. Chugunova, Alexandra D. Voloshina, Rezeda E. Mukhamatdinova, Igor V. Serkov, Alexey N. Proshin, Elmira M. Gibadullina, Alexander R. Burilov, Natalia V. Kulik, Vladimir V. Zobov, Dmitry B. Krivolapov, Alexey B. Dobrynin and Regis Goumont
DOI: 10.2174/1570180810666131122010403
Published on: 21 November, 2013