Letters in Drug Design & Discovery


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:10   Issue: 5
Pp: i-v

DOI: 10.2174/1570180811310050001

The Activity of Titanocene T Against Xenografted Caki-1 Tumors

Volume:10   Issue: 5
Pp: 375-381
Wolfgang Walther, Iduna Fichtner, Anthony Deally, Megan Hogan and Matthias Tacke
DOI: 10.2174/1570180811310050002

The Venom of the Centipede Scolopendra subspinipes mutilans Inhibits the Growth of Myelogenous Leukemia Cell Lines

Volume:10   Issue: 5
Pp: 390-395
Shiyan Xu, Fan Zhang, Hengyun Wang, Yu Liu, Dan Li, Zhe Wu and Zhonghua Liu
DOI: 10.2174/1570180811310050004

Further Insights in 5-phenyl-2-[2-(1-piperidinylcarbonyl) Phenyl]-2,3- dihydro-1H-pyrrolo[1,2-c]imidazol-1-ones, a Recently Disclosed Class of Neuropeptide S Antagonists

Volume:10   Issue: 5
Pp: 396-401
Gabriele Costantino, Marco Mor, Chiara Pecchini, Gian Paolo Vallerini, Elisa Della Turca, Fabrizio Micheli, Angela Worby, Romano Di Fabio, Angelo Giacometti, Adelheid Roth, Emilio Merlo-Pich, Matteo Biagetti, Giorgio Bonanomi, Dino Montanari, Luca Tarsi, Federica Tonelli, Raffaele Longhi and Anna Maria Capelli
DOI: 10.2174/1570180811310050005

Preparation and Cytotoxic Activities of Fatty Acid Derivatives of 20(S)- Protopanaxatriol

Volume:10   Issue: 5
Pp: 402-409
Nan-Nan Qiu, Jie Hu, Jin-Ping Liu, Fang Wang and Ping-Ya Li
DOI: 10.2174/1570180811310050006

Glyoxalase 1 and 2 Enzyme Inhibitory Activity of 6-Sulfamoylsaccharin and Sulfocoumarin Derivates

Volume:10   Issue: 5
Pp: 410-414
Marina Makrecka, Raivis Zalubovskis, Edijs Vavers, Jekaterina Ivanova, Aiga Grandane and Maija Dambrova
DOI: 10.2174/1570180811310050007

Aldose Reductase Inhibitory Potential of Several Thiazolyl-thiazolidine- 2,4-Diones

Volume:10   Issue: 5
Pp: 415-419
Net Das-Evcimen, Mutlu Sarıkaya, A. Selen Gurkan-Alp and Oya Bozdag-Dundar
DOI: 10.2174/1570180811310050008

Design, Synthesis and Evaluation of Quinoline-based Small Molecule Inhibitor of STAT3

Volume:10   Issue: 5
Pp: 420-426
Zhi-Bing Shi, Lei Zhang, Zheng-Yang Bin, Xiang-Rong Cao, Zhu-Nan Gong and Jian-Xin Li
DOI: 10.2174/1570180811310050009

QSAR Studies of Tetranortriterpenoid: An Analysis Through CoMFA and CPSA Parameters

Volume:10   Issue: 5
Pp: 427-436
K. Arvind, K. Anand Solomon and S.S. Rajan
DOI: 10.2174/1570180811310050010

Purification and Biological Evaluation of Some Bioactive Metabolomics as Antimicrobial Agent

Volume:10   Issue: 5
Pp: 437-443
Ramar Perumal Samy, Gautam Sethi and Vincent T.K Chow
DOI: 10.2174/1570180811310050011

Design, Synthesis, Crystal Structure, and Antimicrobial Evaluation of Novel Pyrazolyl-1,3,5-oxadiazoles, Pyrazolyl-1,2,4-triazoles and their Related Thioglycosides

Volume:10   Issue: 5
Pp: 444-452
Nora M. A. El-Ebiary, Emad M. El-Telbani, Randa H. Swellem, Ibrahim F. Zeid and Galal A. M. Nawwar
DOI: 10.2174/1570180811310050012

Synthesis and Biological Evaluation of some Amide Derivatives Bearing Benzothiazole and Piperidine Moieties as Antimicrobial Agents

Volume:10   Issue: 5
Pp: 453-461
Mehlika Dilek Altintop, Ahmet Ozdemir, Zafer Asim Kaplancikli, Gulhan Turan-Zitouni, Gokalp Iscan and Gulsen Akalin Ciftci
DOI: 10.2174/1570180811310050013

Synthesis and Biological Evaluation of Piperazinyl-2-(Benzo)thiophen/- furan-2-yl-acetonitriles as Strecker Reaction Products

Volume:10   Issue: 5
Pp: 462-470
Rahul V. Patel, Jigar K. Patel, Shivraj H. Nile and Se Won Park
DOI: 10.2174/1570180811310050014

Antimycobacterial Activity: Synthesis and Biological Evaluation of Novel Substituted (3E,5E)-3,5-diarylidene-1-phenethylpiperidine-4-one Derivatives

Volume:10   Issue: 5
Pp: 471-476
Mohamed Ashraf Ali, Venu Sanjeevi Lakshmipathi, Farzana Beevi, Raju Suresh Kumar, Rusli Ismail, Tan Soo Choon, Ang Chee Wei, Yeong Keng Yoon and Alireza Basiri
DOI: 10.2174/1570180811310050015