Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 1 Issue: 3, July

Graphical Abstracts

Volume:1   Issue: 3
Pp: vi-vi

DOI: 10.2174/15701808104010300vi
Published on: 01 March, 2012

Entry Inhibitors - A New Class of Aids Drugs

Volume:1   Issue: 3
Pp: 184-193
Marcus Vinicius Nora De Souza
DOI: 10.2174/1570180043398786
Published on: 01 March, 2012

First Inhibitors of the Steroidogenic Enzyme Type 7 17β-Hydroxysteroid Dehydrogenase

Volume:1   Issue: 3
Pp: 194-197
E. Bellavance, V. Luu-The and D. Poirier
DOI: 10.2174/1570180043398867
Published on: 01 March, 2012

Cytotoxicity of 5H-Dibenzo[c,h][1,6]naphthyridin-6-ones and 6H-Indeno[1,2-c]isoquinolin-5,11-diones in Tumor Cells Sensitive and Resistant to Camptothecin Analogs

Volume:1   Issue: 3
Pp: 198-202
Alexander L. Ruchelman, Sudhir K. Singh, Angela Liu, Nai Zhou, Leroy F. Liu and Edmond J. La Voie
DOI: 10.2174/1570180043399064
Published on: 01 March, 2012

Peptide Based Vaccine Design for Cancer Immunotherapy

Volume:1   Issue: 3
Pp: 203-210
D. S. Pouniotis, J. Halton and V. Apostolopoulos
DOI: 10.2174/1570180043398894
Published on: 01 March, 2012

Chemogenomic Investigation of AP-1 Transcriptional Regulation of LTC4 Synthase Expression

Volume:1   Issue: 3
Pp: 211-216
Tiana Chong, Michael McMillan, Jia Ling Teo, William R. Henderson Jr. and Michael Kahn
DOI: 10.2174/1570180043398920
Published on: 01 March, 2012

Advanced Pharmacophore Model of Non-Competitive AMPA Antagonist 2,3-benzodiazepines

Volume:1   Issue: 3
Pp: 217-223
B. Rezessy and S. Solyom
DOI: 10.2174/1570180043398948
Published on: 01 March, 2012

Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity

Volume:1   Issue: 3
Pp: 224-229
A. Anaflous, N. Benchat, M. Mimouni, S. Abouricha, T. Ben-Hadda, B. El-Bali, A. Hakkou and B. Hacht
DOI: 10.2174/1570180043398885
Published on: 01 March, 2012

Antimicrobial Peptides from Animals: Focus on Drug Discovery

Volume:1   Issue: 3
Pp: 230-236
L. P. Silva
DOI: 10.2174/1570180043399028
Published on: 01 March, 2012

Proteomics to Identify Novel Biomarkers and Therapeutic Targets in Cardiovascular Disease

Volume:1   Issue: 3
Pp: 237-246
Markus Kubicek, Silvia M. Sanz-Gonzalez, Francisco Verdeguer and Vicente Andres
DOI: 10.2174/1570180043398975
Published on: 01 March, 2012

Doxsaliform: A Novel N-Mannich Base Prodrug of a Doxorubicin Formaldehyde Conjugate

Volume:1   Issue: 3
Pp: 247-255
P. S. Cogan, C. R. Fowler, G. C. Post and T. H. Koch
DOI: 10.2174/1570180043399000
Published on: 01 March, 2012

New Drug Design for Gene Therapy - Taking Advantage of Introns

Volume:1   Issue: 3
Pp: 256-262
Shi-Lung Lin and Shao-Yao Ying
DOI: 10.2174/1570180043398939
Published on: 01 March, 2012

Apoptosis Signaling Pathways as Therapeutic Targets in Lung Injury

Volume:1   Issue: 3
Pp: 263-268
Kazuyoshi Kuwano, Naoki Hagimoto, Michihiro Yoshimi, Takashige Maeyama and Yoichi Nakanishi
DOI: 10.2174/1570180043398849
Published on: 01 March, 2012

Atorvastatin Therapy Increases Monocyte / Macrophage Paraoxonase 2 Expression and Reduces Oxidative Stress in Hyprecholesterolemic Patients

Volume:1   Issue: 3
Pp: 269-274
Rosenblat Mira, Hayek Tony, Hussein Khetam and Michael Aviram
DOI: 10.2174/1570180043399046
Published on: 01 March, 2012

A Stereospecific Route for the Preparation of Trans-Combretastatin Analogs: Synthesis and Cytotoxicity

Volume:1   Issue: 3
Pp: 275-278
Hari Pati, Zarmeen Taherbhai, Lori Forrest, Martha Wicks, Suzanna Bailey, Andrew Staples, Michelle Stewart, William Pennington, Jeffrey Harris and Moses Lee
DOI: 10.2174/1570180043398821
Published on: 01 March, 2012

Prevention of Cell Damage in Ischaemic-Reperfusion: Mitochondrial Respiratory Chain as a Pharmacological Target

Volume:1   Issue: 3
Pp: 279-284
D. Morin, R. Zini, J. P. Tillement and A. Berdeaux
DOI: 10.2174/1570180043398803
Published on: 01 March, 2012

Amide Mono Thioxylated Derivatives of MEN 10627

Volume:1   Issue: 3
Pp: 285-288
M. Altamura, G. Balacco, A. Giolitti, A. Guidi, R. Patacchini, A. R. Renzetti, A. Triolo and C. A. Maggi
DOI: 10.2174/1570180043398966
Published on: 01 March, 2012

Rabies Vaccines: The Third Generation

Volume:1   Issue: 3
Pp: 289-292
T. Vanniasinkam and H. C. J. Ertl
DOI: 10.2174/1570180043398911
Published on: 01 March, 2012