Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Editor's Choice

Chitosan: A Promising Protective Component Against SARS-CoV-2 and Influenza Virus

Volume: 18   Issue: 5
Pp: 418-421
Mohammad Reza Rahbar, Hadi Esmaeili Gouvarchin Galeh, Saeed Khalili and Abolfazl Jahangiri*
DOI: 10.2174/1570180817999201110114446

General Perspectives for the Treatment of Atherosclerosis

Volume: 18   Issue: 4
Pp: 314-324
Hayrettin Ozan Gülcan and Ilkay Erdogan Orhan*
DOI: 10.2174/1570180817999201016154400

Expanding Opportunities in Treatment of Leukemia by Solid Lipid Nanoparticles

Volume: 18   Issue: 3
Pp: 212-221
Prarthna Yadav, Harshita Mishra, Manju Nagpal and Geeta Aggarwal*
DOI: 10.2174/1570180817999201001155508

Sulfonamides and Sulphonyl Ester of Quinolines as Non-Acidic, Non- Steroidal, Anti-inflammatory Agents

Volume: 18   Issue: 2
Pp: 112-120
Bilquees Bano, Kanwal, Khalid Mohammed Khan*, Almas Jabeen, Aisha Faheem, Muhammad Taha, Syed Moazzam Haider and Shahnaz Perveen
DOI: 10.2174/1570180817999201005201308

Novel Coronavirus 2019 Outbreak: A Global Epidemic

Volume: 17   Issue: 12
Pp: 1458-1464
Sweta Kamboj*, Rohit Kamboj, Shikha Kamboj, Kumar Guarve and Rohit Dutt
DOI: 10.2174/1570180817999200802033916

Evaluation of Kaempferol as AKT Dependent mTOR Regulator via Targeting FKBP-12 in Hepatocellular Carcinoma: An In silico Approach

Volume: 17   Issue: 11
Pp: 1401-1408
Pooja Siniprasad, Bhagyalakshmi Nair, Vaisali Balasubramaniam, Prashanth Sadanandan, Puliyapally Krishnan Namboori* and Lekshmi Reghu Nath*
DOI: 10.2174/1570180817999200623115703

Anti-inflammatory Augmentation Therapy in Obsessive-compulsive Disorder: A Review

Volume: 17   Issue: 10
Pp: 1198-1205
Hanie Ghasemi, Homa Nomani, Amirhossein Sahebkar* and Amir Hooshang Mohammadpour*
DOI: 10.2174/1570180817999200520122910

Natural Sesquiterpene Lactones in the Prevention and Treatment of Inflammatory Disorders and cancer: A Systematic Study of this Emerging Therapeutic Approach based on Chemical and Pharmacological Aspect

Volume: 17   Issue: 9
Pp: 1102-1116
Sudip Kumar Mandal, Utsab Debnath, Amresh Kumar, Sabu Thomas, Subhash Chandra Mandal, Manabendra Dutta Choudhury and Partha Palit*
DOI: 10.2174/1570180817999200421144007

Structure-based Drug Design Strategies in the Development of Small Molecule Inhibitors Targeting Bcl-2 Family Proteins open access plus

Volume: 17   Issue: 8
Pp: 943-953
Zhe Yin, Donglin Yang, Jun Wang and Yuequan Jiang*
DOI: 10.2174/1570180817666200213114759

In Silico ADME and QSAR Studies on a Set of Coumarin Derivatives As Acetylcholinesterase Inhibitors Against Alzheimer’s Disease: CoMFA, CoMSIA, Topomer CoMFA, and HQSAR

Volume: 17   Issue: 6
Pp: 684-712
Uttam Ashok More*, Sameera Patel, Vidhi Rahevar, Malleshappa Ningappa Noolvi, Tejraj M. Aminabhavi and Shrinivas D. Joshi
DOI: 10.2174/1570180816666190712095907

Bimetallic Catalyzed N-arylation Used in Synthesis of Novel β-carbolines Derivatives

Volume: 17   Issue: 5
Pp: 520-525
Rui Cai , Li Zhu, Pengfei Wang and Yu Zhao*
DOI: 10.2174/1570180815666181025124615

Carbon Nanotubes Enhance the Chemotherapy Sensitivity of Tumors with Multidrug Resistance open access plus

Volume: 17   Issue: 4
Pp: 366-378
Zhijie Wang, Jinhua Tao, Jianan Chen and Qian Liu*
DOI: 10.2174/1570180816666190405110858

Nitric Oxide Synthases and Their Inhibitors: A Review

Volume: 17   Issue: 3
Pp: 228-252
Anshika Mittal and Rita Kakkar*
DOI: 10.2174/1570180816666190222154457

Progress in Synthesis and Bioactivity Evaluation of Pyrazoloquinazolines

Volume: 17   Issue: 2
Pp: 104-113
Hui Zhao, Xiaoxia Hu, Yue Zhang, Chunlei Tang* and Bainian Feng*
DOI: 10.2174/1570180815666181017120100

Targeting Inflammation with Conjugated Cinnamic Amides, Ethers and Esters

Volume: 17   Issue: 1
Pp: 3-11
Ioannis Fotopoulos, Eleni Pontiki and Dimitra Hadjipavlou Litina*
DOI: 10.2174/1570180816666181129125511

Insights Into the Explication of Potent Tyrosinase Inhibitors with Reference to Computational Studies

Volume: 16   Issue: 11
Pp: 1182-1193
Naima Parveen, Sharique Akhtar Ali* and Ayesha Sharique Ali
DOI: 10.2174/1570180815666180803111021

Molecular Modeling of an Orphan GPR18 Receptor

Volume: 16   Issue: 10
Pp: 1167-1174
Kamil J. Kuder, Tadeusz Karcz, Maria Kaleta and Katarzyna Kiec-Kononowicz*
DOI: 10.2174/1570180815666180810114847

The Structure of MT189-Tubulin Complex Provides Insights into Drug Design open access plus

Volume: 16   Issue: 9
Pp: 1069-1073
Zhongping Li, Lingling Ma, Chengyong Wu, Tao Meng, Lanping Ma, Wenyue Zheng, Yamei Yu*, Qiang Chen*, Jinliang Yang and Jingkang Shen
DOI: 10.2174/1570180816666181122122655

Paclitaxel-tyroserleutide Conjugates Self-assembly into Nanocarrier for Drug Delivery

Volume: 16   Issue: 8
Pp: 882-891
Yongjia Liu, Leilei Shi, Bangshang Zhu*, Yue Su, Hui Li* and Xinyuan Zhu
DOI: 10.2174/1570180815666180803124625