Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Most Accessed Articles

Design and Efficient Synthesis of Novel 4,5-Dimethylthiazole-Hydrazone Derivatives and their Anticancer Activity

Volume: 18   Issue: 4
Pp: 372-386
Asaf Evrim Evren*, Leyla Yurttaş, Büşra Ekselli, Onur Aksoy and Gülşen Akalin-Çiftçi
DOI: 10.2174/1570180817999201022192937

Virtual Screening of Chinese Medicine Small Molecule Compounds Targeting SARS-CoV-2 3CL Protease (3CL pro)

Volume: 18   Issue: 4
Pp: 355-364
Qingxiu He, Xin Chen, Xi Yang, Guangpin Li, Haiqiong Guo, Han Chu, Zhihua Lin* and Yuanqiang Wang*
DOI: 10.2174/1570180817999201001161017

Chitosan: A Promising Protective Component Against SARS-CoV-2 and Influenza Virus

Volume: 18   Issue: 5
Pp: 418-421
Mohammad Reza Rahbar, Hadi Esmaeili Gouvarchin Galeh, Saeed Khalili and Abolfazl Jahangiri*
DOI: 10.2174/1570180817999201110114446

General Perspectives for the Treatment of Atherosclerosis

Volume: 18   Issue: 4
Pp: 314-324
Hayrettin Ozan Gülcan and Ilkay Erdogan Orhan*
DOI: 10.2174/1570180817999201016154400

Novel N-(2-Methoxydibenzofuran-3-yl)-2-aryloxyacetamide Derivatives: Synthesis and Biological Investigation

Volume: 18   Issue: 5
Pp: 471-479
Leyla Yurttaş*, Betül Kaya Çavuşoğlu, Halide Edip Temel and Gülşen Akalın Çiftçi
DOI: 10.2174/1570180817999201110114107

1'-methylspiro[indoline-3,4'-piperidine] Derivatives: Design, Synthesis, Molecular Docking and Anti-tumor Activity Studies

Volume: 18   Issue: 5
Pp: 490-498
Junjian Li, Lianbao Ye*, Yuanyuan Wang, Ying Liu, Xiaobao Jin and Ming Li
DOI: 10.2174/1570180817999201117150714

Bioactive Isolates of Morus Species as Antibacterial Agents and their In Silico Profiling

Volume: 18   Issue: 5
Pp: 445-453
Aditya Shimoga Janakirama Rao, Venugopal Thegur Mudduraj Urs, Jayanna Nayakarahatty Devanna, Paramesha Mahadevappa and Ramesh Chapeyil Kumaran*
DOI: 10.2174/1570180817999201104120815

Synthesis, Cytotoxicity, Antioxidant and Antimicrobial Activity of Indole Based Novel Small Molecules

Volume: 18   Issue: 5
Pp: 461-470
Aslıhan Kurt-Kızıldoğan, Çiğdem Otur, Can Yılmaz, Sevki Arslan, Dogukan Mutlu, Arif Kivrak*, Muheb Algso, Abdussamet Kayhan, Doğan Çetin and Metin Konus*
DOI: 10.2174/1570180817999201109203226

Novel Carbamοyloxy Analogues of Tamoxifen: Synthesis, Molecular Docking and Bioactivity Evaluation

Volume: 18   Issue: 5
Pp: 422-428
Konstantinos M. Kasiotis*, George Lambrinidis, Nikolas Fokialakis and Serkos A. Haroutounian
DOI: 10.2174/1570180817999201104125630

Design, Synthesis, and Biological Evaluation of Novel Tetramethylpyrazine- nitrone Derivatives as Antioxidants

Volume: 18   Issue: 5
Pp: 499-508
Haiyun Chen*, Chunyan Yan*, Jie Cao, Zheng Liu, Yewei Sun and Yuqiang Wang
DOI: 10.2174/1570180817999201117145311

Design and Synthesis of Novel 5-Arylisoxazole-1,3,4-thiadiazole Hybrids as α-Glucosidase Inhibitors

Volume: 18   Issue: 5
Pp: 436-444
Mina Saeedi, Azadeh Eslami, Seyedeh Sara Mirfazli, Mahsa Zardkanlou, Mohammad Ali Faramarzi, Mohammad Mahdavi and Tahmineh Akbarzadeh*
DOI: 10.2174/1570180817999201104125018

Potential Inhibition of COVID-19 RNA-dependent RNA Polymerase by Hepatitis C Virus Non-nucleoside Inhibitors: An In-silico Perspective

Volume: 18   Issue: 5
Pp: 429-435
Yee Siew Choong*, Theam Soon Lim, Hanyun Liu, Rubin Jiang, Zimu Cai and Yuan Ge*
DOI: 10.2174/1570180817999201104123750