Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Most Cited Article

(Substituted)-benzo[b]thiophene-4-carboxamide Synthesis and Antiproliferative Activity Study

Volume:17   Issue:5
Pp: 563-573
Chandrakant Dhondiram Pawar, Dattatraya Navnath Pansare and Devanand Baburao Shinde*
DOI: 10.2174/1570180815666181004114125

New 2-Oxopyridine/2-Thiopyridine Derivatives Tethered to a Benzotriazole with Cytotoxicity on MCF7 Cell Lines and with Antiviral Activities

Volume:17   Issue:2
Pp: 124-137
Adel Mahmoud Attia, Ahmed Ibrahin Khodair*, Eman Abdelnasser Gendy, Mohammed Abu El-Magd and Yaseen Ali Mosa Mohamed Elshaier*
DOI: 10.2174/1570180816666190220123547

Antimicrobial Activity, Antioxidant Properties and Phytochemical Screening of Aesculus hippocastanum Mother Tincture against Food-borne Bacteria

Volume:17   Issue:1
Pp: 48-56
Maria Grazia Bonomo*, Caterina Cafaro, Daniela Russo, Luana Calabrone, Luigi Milella, Carmela Saturnino, Anna Capasso and Giovanni Salzano
DOI: 10.2174/1570180816666181108114115

Lead Molecules as Novel Aromatase Inhibitors: In Silico De Novo Designing and Binding Affinity Studies

Volume:17   Issue:5
Pp: 655-665
Laxmi Banjare, Sant Kumar Verma, Akhlesh Kumar Jain and Suresh Thareja*
DOI: 10.2174/1570180816666190703152659

Synthesis and Antimicrobial Activity of Thiohydantoins Obtained from L-Amino Acids

Volume:17   Issue:1
Pp: 94-102
Priscila Goes Camargo de Carvalho, Jhonatan Macedo Ribeiro, Renata Perugini Biasi Garbin, Gerson Nakazato, Sueli Fumie Yamada Ogatta, Ângelo de Fátima, Marcelle de Lima Ferreira Bispo and Fernando Macedo*
DOI: 10.2174/1570180816666181212153011

QSAR Analysis of Selected Antimicrobial Structures Belonging to Nitro-derivatives of Heterocyclic Compounds

Volume:17   Issue:2
Pp: 214-225
Piotr Kawczak*, Leszek Bober and Tomasz Bączek
DOI: 10.2174/1570180815666181004112947

Synthesis and Biological Evaluation of Benzodioxol Derivatives as Cyclooxygenase Inhibitors

Volume:17   Issue:9
Pp: 1117-1125
Nidal Jaradat*, Mohammed Hawash and Murad Abualhasan
DOI: 10.2174/1570180817999200420114402

Novel Coronavirus (COVID-19) Outbreak: Hope and Search for Effective Therapeutic Agent

Volume:17   Issue:8
Pp: 940-942
Saurabh Kumar*
DOI: 10.2174/1570180817999200612095513

An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation

Volume:17   Issue:2
Pp: 138-144
Sanal Dev, Della Grace Thomas Parambi, Bency Baby, Githa Elizabeth Mathew, Hendawy Omnia Magdy, Monu Joy, Shine Sudev and Bijo Mathew*
DOI: 10.2174/1570180815666181016155934

Synthesis of Piperidine Conjugated Dihydroquinazolin-4(1H)-ones and their Antiproliferative Activity, Molecular Docking Studies and DFT Calculations open access plus

Volume:17   Issue:1
Pp: 85-93
Kereyagalahally Honneshappa Narasimhamurthy, Chandra, Toreshettahally Ramesh Swaroop, Swamy Jagadish and Kanchugarakoppal Subbegowda Rangappa*
DOI: 10.2174/1570180816666190613120349

One-pot Synthesis of Betulin Triterpenoid Quaternized Pyridine Derivatives and their Antimicrobial Activity

Volume:17   Issue:1
Pp: 79-84
Elvira Rifovna Shakurova, Darina Alexandrovna Pozdnyakova, Elena Valeryevna Tretyakova and Lyudmila Vyacheslavovna Parfenova*
DOI: 10.2174/1570180816666181217123629

Fingerprint-based 2D-QSAR Models for Predicting Bcl-2 Inhibitors Affinity

Volume:17   Issue:10
Pp: 1206-1215
Said Byadi, Hachim Mouhi Eddine, Karima Sadik, Črtomir Podlipnik and Aziz Aboulmouhajir*
DOI: 10.2174/1570180817999200414155403

Natural Sesquiterpene Lactones in the Prevention and Treatment of Inflammatory Disorders and cancer: A Systematic Study of this Emerging Therapeutic Approach based on Chemical and Pharmacological Aspect

Volume:17   Issue:9
Pp: 1102-1116
Sudip Kumar Mandal, Utsab Debnath, Amresh Kumar, Sabu Thomas, Subhash Chandra Mandal, Manabendra Dutta Choudhury and Partha Palit*
DOI: 10.2174/1570180817999200421144007