Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Most Accessed Articles

Rationale Design, Synthesis, and Pharmacological Evaluation of Isatin Analogues as Antiseizure Agents

Volume: 18   Issue: 12
Pp: 1146-1164
Sandip Firke, Rameshwar Cheke , Vinod Ugale*, Saurabh Khadse , Manish Gagarani, Sanjay Bari and Sanjay Surana
DOI: 10.2174/1570180818666210804145014

Discovery of Structural Prospects of Imidazo[1,5-a]pyrazine Derivatives as BTK Inhibitors Against Cancer: A Computational Study open access plus

Volume: 18   Issue: 12
Pp: 1165-1177
Amena Ali*, Abuzer Ali and Mohamed Jawed Ahsan
DOI: 10.2174/1570180818666210802104517

Synthesis of Chromen-1-phenylpropan-1-one Derivatives and their Antidepressant/ Anticonvulsant Activities

Volume: 18   Issue: 12
Pp: 1136-1145
Shan-Shan Zhang, Wei-Hua Liu, Zhi-Wen He, Qiu-Wan Tan and Li-Ping Guan*
DOI: 10.2174/1570180818666210804143223

Investigating the Mechanism of Action of Frankincense against Drug- Induced Liver Injury Using Network Pharmacology and Molecular Docking

Volume: 18   Issue: 10
Pp: 976-986
Yu-cheng Liao, Jing-wen Wang, Qian Yang, Wen-jun Wanga, Chao Zhao, Lian Sun, Ai-dong Wen*, Rui-li Li* and Yi Ding*
DOI: 10.2174/1570180818666210319160217

In Silico and In Vitro Analysis of a Multiepitope L1-E7 Fusion Construct for Vaccine Development Against Human Papillomaviruses

Volume: 18   Issue: 11
Pp: 1061-1093
Elnaz Abbasifarid, Azam Bolhassani*, Shiva Irani and Fattah Sotoodehnejadnematalahi
DOI: 10.2174/1570180818666210602160150

Combinatorics, Big Data, Neural Network & AI for Medicinal Chemistry & Drug Administration promotion: free to download

Volume: 18   Issue: 10
Pp: 943-948
Krishnan Balasubramanian*
DOI: 10.2174/1570180818666210719130052

Prediction of Inhibition Activity of BET Bromodomain Inhibitors using Grid Search-Based Extreme Learning Machine and Molecular Docking

Volume: 18   Issue: 11
Pp: 1039-1049
Oluwatoba Emmanuel Oyeneyin*, Babatunde Samuel Obadawo, Segun Michael Orimoloye, Eric Oluwafisayo Akintemi, Nureni Ipinloju, Adeola M. Asere and Taoreed O. Owolabi
DOI: 10.2174/1570180818666210521215433

Computational Modeling of Aldose Reductase Inhibitory Activity of Flavonoids Derivatives for Diabetic Complications Treatment

Volume: 18   Issue: 11
Pp: 1094-1105
Roberto Díaz-Amador, Yudith Cañizares-Carmenate, Alberto Taboada-Crispi and Juan A. Castillo-Garit*
DOI: 10.2174/1570180818666210604113206

3D-QSAR, Docking, and Molecular Dynamics Simulations Studies on Quinazoline Derivatives as PAK4 Inhibitors

Volume: 18   Issue: 11
Pp: 1025-1038
Xiao-Zhong Chen, Chen Dai , Yan Shen, Juan Wang, Yong Hu, Yuan-Qiang Wang* and Zhi-Hua Lin*
DOI: 10.2174/1570180818666210602155310

Design of Inhibitory Peptides of the Interaction between the RBD Domain of the S1 Protein of SARS-CoV-2 and the Angiotensin-Converting Enzyme 2 (ACE2) Receptor open access plus

Volume: 18   Issue: 7
Pp: 666-673
Carlos Andrés Rodríguez-Salazar*, Delia Piedad Recalde-Reyes and Jhon Carlos Castaño-Osorio
DOI: 10.2174/1570180817999201211192211

New Viral Infection COVID-19: Current Status, Challenges and Possible Treatments

Volume: 18   Issue: 7
Pp: 635-649
Vipan Kumar, Amruta Suryan, Jyoti Singh*, Sandeep Kumar, Pradeep Kamboj and Aakash Deep
DOI: 10.2174/1570180818999201224120233

Diagnostic, Prognostic and Therapeutic Potential of Heat Shock Proteins in Schistosomiasis and Bladder Cancer: A Review

Volume: 18   Issue: 7
Pp: 650-665
Ndibonani Kebonang Qokoyi, Priscilla Masamba, Geraldene Munsamy and Abidemi Paul Kappo*
DOI: 10.2174/1570180818999201228205317

Synthesis of Chrysin, Quercetin and Naringin Nitroderivatives: Antiproliferative, Anti-inflammatory and Antioxidant Activity

Volume: 18   Issue: 8
Pp: 795-805
Rosario Tavera-Hernández, Manuel Jiménez-Estrada*, Jesús J. Alvarado-Sansininea, Antonio Nieto-Camacho, Hugo López-Muñoz, Luis Sánchez-Sánchez and María L. Escobar
DOI: 10.2174/1570180818666210122162313

Modifications of Isoalantolactone Leading to Effective Anti-bacterial and Anti-viral Compounds

Volume: 18   Issue: 7
Pp: 686-700
Sergey S. Patrushev, Lyubov G. Burova, Anna A. Shtro, Tatyana V. Rybalova, Dmitry S. Baev, Il’ya V. Shirokikh, Alexander N. Evstropov and Elvira E. Shults*
DOI: 10.2174/1570180817999201211193151