ISSN (Print): 1871-5265
ISSN (Online): 2212-3989
Volume 21, 8 Issues, 2021
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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989
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Editor(s): Marcelo Santos da Silva and Maria Isabel N. Cano
eISBN: 978-1-68108-405-3, 2017
ISBN: 978-1-68108-406-0 ISSN: 2452-4211 (Print) ISSN: 2542-422X (Online)
Frontiers in Parasitology is an Ebook series devoted to publishing the latest and the most important advances in parasitology. Eminent scientists present reviews on the microbiology, cytology, epidemiology, genomics, and molecular biology of microbial parasites and their associated infections. Additionally, the series also gives information about new diagnostic and therapeutic protocols. The Ebook series is essential reading to all scientists involved in studying harmful microbes and their impact on human health.
Editor(s): Fabrizio Bruschi
eISBN: 978-1-68108-433-6, 2017
ISBN: 978-1-68108-434-3 ISSN: 2542-4211 (Print) ISSN: 2542-422X (Online)
Several parasites are able to spread diseases through contaminated water. While the spread of diseases through contaminated water appears to have a greater correlation with a lack of access to clean water in low income populations in developing countries, there have been outbreaks of water-borne diseases in developed countries. Therefore, addressing water-borne diseases is a major public health concern worldwide. Water-borne Protozoa in Humans is a guide to protozoan infections linked to contaminated water.
Each chapter of this monograph covers the history, morphology, life cycle, global epidemiology, risk factors, immunology, symptoms, diagnosis, treatment and perspectives of control for each relevant protozoan parasite that can be found in contaminated water. These include Giardia duodenalis, Cryptosporidium, Free-living amoebae, Entamoeba histolytica/dispar and other pathogenic intestinal amoebae, Cystoisospora belli, cyclospora, microsporidia, and Blastocystis hominis.
This monograph is suitable for a broad readership which includes medical students, parasitologists, clinical microbiologists, epidemiologists, environmental health and water safety technicians, and public health personnel.
Editor(s): Mihail Lucian Pascu
eISBN: 978-1-68108-498-5, 2017
This monograph is a collection of reviews that presents results obtained from new and somewhat unconventional methods used to fight multiple drug resistance (MDR) acquired by microorganisms and tumours. Two directions are considered: (i) the modification of non-antibiotic medicines by exposure to un-coherent, or laser optical radiation to obtain photoproducts that receive bactericidal or, possibly, tumouricidal properties and (ii) the development of new vectors (micrometric droplets of solutions containing medicinal agents) to transport medicines to targets based on optical and micro spectroscopic methods.
Chapters shed light on pendant droplets used for antibiotic drug delivery, the science of lasers and their interactions with fluids in pendant droplets and spectroscopic analyses of droplets used to treat MDR infections. It therefore equips researchers and medical professionals with information about tools that enable them to respond to medical emergencies in challenging environments.
The intended readership for this monograph includes graduate students, medical doctors, fluid physicists, biologists, photochemists, and experts in drug delivery methods employed in extreme conditions (such as those found in outer space and hypergravity conditions) who are learning about using techniques such as laser spectroscopy, biophotonics and optofluidics/microfluidics.
Editor(s): Milena de Paiva Cavalcanti, Valeria Rego Alves Pereira and Alain Joseph Jacques Dessein
eISBN: 978-1-68108-587-6, 2017
Tropical Diseases: An Overview of Major Diseases Occurring in the Americas offers an overview of neglected tropical diseases found in the Americas. Information in the book addresses the understanding of challenges faced in controlling these diseases and brings new insight on many important aspects of these diseases. Chapters of this volume explore many related topics, including epidemiological data, immune response and pathogenesis, and the current methods for diagnosis and treatment, thus providing a useful resource for readers (undergraduate, graduate and Ph.D. students as well as biologists and medical researchers).
Editor(s): Azam Bolhassani
eISBN: 978-1-68108-617-0, 2018
Human papillomavirus (HPV) infection is one of the most frequently sexually transmitted diseases in the world. HPV infections are responsible for almost all cases of genital warts and are also responsible for multiple cancer in different regions of the body. Several studies on HPV diagnosis and vaccine development are in progress. Recently, two commercial vaccines such as Gardasil and Cervarix have been used to prevent HPV infections. Various drugs have also been tested in clinical trials for the treatment of HPV-related cancers.
HPV infections: Diagnosis, Prevention, and Treatment provides a comprehensive overview of diagnosis, prevention and treatment in HPV-related infections. Chapters cover a large range of topics including HPV epidemiology, molecular biology, transmission, diagnosis, prevention, and treatment along with information about preclinical and clinical experiments.
This book is intended as a comprehensive handbook for medical students and residents who require information about HPV and the treatment of HPV related diseases.
Editor(s): Katia Denise Saraiva Bresciani and Alvimar Jose da Costa
eISBN: 978-1-68108-643-9, 2018
Congenital Toxoplasmosis in Humans and Domestic Animals presents information about Toxoplasma gondii and its infection in neonates and different animals (cats, cattle, dogs, goats, pigs and sheep). Readers will have quick access to the pathophysiology, diagnosis, reproductive disorders (such as abortion, neonatal mortality and prematurity) and treatment of both human and veterinary toxoplasmosis. In addition, important aspects for control programs of congenital toxoplasmosis and for maternal and neonatal screening in such control programs are discussed. Thus readers will be better equipped to conduct prevention programmes and routine diagnosis of zoonotic infections related to T. gondii. This handbook is of interest to epidemiologists, doctors, veterinarians and public health specialists.
Editor(s): K. Tamreihao, Saikat Mukherjee and Debananda S. Ningthoujam
eISBN: 978-981-14-3273-6, 2019
ISBN: 978-981-14-3272-9 ISSN: 2705-1072 (Print) ISSN: 2705-1080 (Online)
The volume is a comprehensive documentation on major infectious diseases from tropical countries which pose a serious threat to global healthcare programs. These include diseases such as tuberculosis, AIDS, leishmaniasis (kala-azar), elephantiasis, malaria, leprosy, various fungal disorders and emergent viral diseases. Due to the widespread use of antibiotics, there is an emergence of drug-resistant pathogens in many regions. Hence, there is a need to search for novel, cost-effective bioactive compounds that demonstrate high efficacy and low toxicity in human cells from unexplored ecosystems to combat emerging drug-resistant pathogens. Chapters of this volume focus on the pathogenesis and etiology of each of the mentioned diseases, updated WHO reports wherever applicable, conventional drugs and their pharmacokinetics as well as new approaches to develop anti-infective agents.
Editor(s): Gloria G. Guerrero Manriquez
eISBN: 978-981-14-6958-9, 2020
ISBN: 978-981-14-6956-5 ISSN: 2705-1072 (Print) ISSN: 2705-1080 (Online)
This volume of Frontiers in Anti-Infective Agents provides updates on the most recent studies about anti-infective agents, their mechanism of action, the relevant molecular targets and their implication in the development of novel antibiotics that have properties similar to their corresponding compounds of natural origin. The initial chapter covers the mode of action of natural antimycobacterial compounds such as nordihydroguaiaretic acid, α-mangostin and allicin, as well as antimicrobial peptides and their role in the innate and adaptive immune response leading to the decrease of microbial resistance. This is followed by updates on tuberculosis treatment concerning the immunological role of cells (airway epithelial cells, macrophages, neutrophils and T cells) along with their products (chemokines, cytokines) and other processes such as autophagy that influence the outcome of the host immune response to the infection. Contributors have also reviewed the latest knowledge in the cellular and molecular mechanisms that trigger a protective, immune response and the identification of the molecular targets for vaccine development, all of which are a key priority to develop control measures against Babesia species like Babesia bovis and Babesia bigemina. Additionally, the neuro-endocrine and neuro-immune mechanisms behind host responses against stress and environmental stimuli during infections are also covered in separate chapters. The volume also provides updates related to Helicobacter pylori pathogenesis. The reviews presented in Anti-infective Research and Development provide timely updates for scholars and professionals associated with the field of antimicrobial research and development.
Editor(s): Ricardo Ney Cobucci
eISBN: 978-981-14-7959-5, 2020
ISBN: 978-981-14-7957-1 ISSN: 2705-1072 (Print) ISSN: 2705-1080 (Online)
This concise clinical reference facilitates health consultants and professionals for determining treatment options for some common prenatal and postpartum infections during pregnancy and the puerperium in patients.
- Presents 9 organized, easy to read chapters on anti-infective agents for pregnant patients
- Covers pharmacokinetics and pharmacodynamics of relevant anti-infective agents
- Includes information on classification and safety of anti-infective agents
- Includes treatment of urinary tract infections
- Covers medications for sexually transmitted diseases, including a complete section dedicated to HIV medication
- Provides information about vulvovaginal infections
- Covers the treatment of toxoplasmosis in pregnancy
- innovates with information about herbal remedies for infection for patients during pregnancy and breastfeeding
Pregnancy and Anti-Infective Agents is therefore, a valuable handbook that enables quick consultation on safe antibiotics for the treatment of a variety of infections in pregnancy.
Editor(s): Islam M. Ghazi and Michael J. Cawley
eISBN: 978-981-14-6183-5, 2020
ISBN: 978-981-14-3383-2 ISSN: 2705-1072 (Print) ISSN: 2705-1080 (Online)
21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control.
- 14 organized chapters on several aspects of antimicrobial therapy and stewardship
- Introductory knowledge on global antimicrobial trends
- Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes
- Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools
- Information on unmet needs of patients and clinicians, including the treatment of difficult infections
- Comprehensive coverage of issues in antimicrobial stewardship
21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers – healthcare administrators, educators, pharmacists, clinicians and students, alike – the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistance.
Editor(s): Muhammad Imran Qadir
eISBN: 978-981-14-7376-0 , 2020
Bacterial Diseases provides readers an overview of a broad variety of bacterial infections. Chapters cover the description of specific disease and its causative agent, followed by information about symptoms, diagnosis and clinical management. This easy-to-read resource is a suitable introductory textbook for pharmacy, medical, and dental students, as well as M Phil, and Ph.D. candidates for Pharmacology, Botany, Zoology, Microbiology, Pharmacy, Biotechnology and allied health science programs. Readers interested in a simple clinical summary of bacterial diseases can also benefit from the information provided.
- Coverage of a broad spectrum of bacterial infections over 41 topical chapters
- Easy-to-read presentation which provides a basic description of diseases covered to clinical diagnosis and management
- Emphasis on the route of infection
- References for further reading
Author(s): Rafael Laniado-Laborín
eISBN: 978-981-14-8851-1, 2020
Tuberculosis is an infection of the lungs caused by Mycobacterium tuberculosis and related species. It is prevalent in tropical regions and continues to occur in more than 10 million new individuals annually and despite many advances in medicine, still results in 1.3 million deaths annually.
This clinical practice handbook presents information on all topics related to the disease, including its epidemiology, microbiology, clinical features, diagnostic procedures, treatments, BCG vaccination and infection control in health facilities. Special topics such as the treatment of tuberculosis is pediatric patients, surgery, multi-drug resistance and adverse reactions to tuberculosis drugs are also covered. Information is presented in 16 simple easy-to read chapters with key figures, tables and references that help to explain relevant topics.
Tuberculosis: A Clinical Practice Guide is an ideal reference manual for medical students and healthcare personnel seeking information about tuberculosis.