Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Most Accessed Articles

Synthesis and Evaluation of Glycyrrhetic Acid-aromatic Hybrids as Anti-inflammatory Agents

Volume: 16   Issue: 6
Pp: 715-723
Zhi Chen, Shi-Chao Chen, Bo Li, Yong-An Yang and Jing Zhang*
DOI: 10.2174/1573406415666190603095502

Identification of Novel Functionalized Carbohydrazonamides Designed as Chagas Disease Drug Candidates

Volume: 16   Issue: 6
Pp: 774-783
Mayara S.S. do Nascimento, Vitória R.F. Câmara, Juliana S. da Costa, Juliana M.C. Barbosa, Alessandra S.M. Lins, Kelly Salomão, Solange L. de Castro, Samir A. Carvalho, Edson F. da Silva and Carlos A.M. Fraga*
DOI: 10.2174/1573406415666190627103013

Design of Inhibitors for Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Enzyme of Leishmania mexicana

Volume: 16   Issue: 6
Pp: 784-795
Krisnna M.A. Alves, Fábio José Bonfim Cardoso, Kathia M. Honorio and Fábio A. de Molfetta*
DOI: 10.2174/1573406415666190712111139

2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management

Volume: 16   Issue: 6
Pp: 826-840
Saeed Ullah, Salma Mirza, Uzma Salar, Shafqat Hussain, Kulsoom Javaid, Khalid M. Khan*, Ruqaiya Khalil, Atia-tul-Wahab, Zaheer Ul-Haq, Shahnaz Perveen and Muhammad I. Choudhary
DOI: 10.2174/1573406415666190612153150

A New Reactive Ketenaminal: Synthesis, Coupling Reaction, Tautomeric Study, Docking and Antimicrobial Evaluation of the Products

Volume: 16   Issue: 6
Pp: 761-773
Huda K. Mahmoud, Hanadi A. Katouah, Marwa F. Harras and Thoraya A. Farghaly*
DOI: 10.2174/1573406415666190716153425

Synthesis, In vitro α-Glucosidase Inhibitory Potential and Molecular Docking Studies of 2-Amino-1,3,4-Oxadiazole Derivatives

Volume: 16   Issue: 6
Pp: 724-734
Hayat Ullah, Fazal Rahim, Muhammad Taha*, Raffaqat Hussain, Abdul Wadood, Mohsan Nawaz, Zainul Wahab, Kanwal and Khalid M. Khan
DOI: 10.2174/1573406415666190612150447

Synthesis, Anticancer Activity on Prostate Cancer Cell Lines and Molecular Modeling Studies of Flurbiprofen-Thioether Derivatives as Potential Target of MetAP (Type II)

Volume: 16   Issue: 6
Pp: 735-749
Özgür Yılmaz, Burak Bayer, Hatice Bekçi, Abdullahi I. Uba, Ahmet Cumaoğlu, Kemal Yelekçi and Ş. Güniz Küçükgüzel*
DOI: 10.2174/1573406415666190613162322

Methoxychalcones: Effect of Methoxyl Group on the Antifungal, Antibacterial and Antiproliferative Activities

Volume: 16   Issue: 7
Pp: 881-891
Beatriz C. Marques, Mariana B. Santos, Daiane B. Anselmo, Diego A. Monteiro, Eleni Gomes, Marilia F.C. Saiki, Paula Rahal, Pedro L. Rosalen, Janaina C.O. Sardi and Luis O. Regasini*
DOI: 10.2174/1573406415666190724145158

Synthesis and Antitrypanosomal Profile of Novel Hydrazonoyl Derivatives

Volume: 16   Issue: 4
Pp: 487-494
Natália N. Santiago, Giulianna P. de Alcântara, Juliana S. da Costa, Samir A. Carvalho, Juliana M.C. Barbosa, Kelly Salomão, Solange L. de Castro, Henrique M.G. Pereira and Edson F. da Silva*
DOI: 10.2174/1573406415666190712115237

Computational Analysis and Synthesis of Syringic Acid Derivatives as Xanthine Oxidase Inhibitors

Volume: 16   Issue: 5
Pp: 643-653
Neelam Malik, Anurag Khatkar* and Priyanka Dhiman
DOI: 10.2174/1573406415666191004134346

Dairy Safety Prediction Based on Machine Learning Combined with Chemicals

Volume: 16   Issue: 5
Pp: 664-676
Jiahui Chen, Guangya Zhou, Jiayang Xie, Minjia Wang, Yanting Ding, Shuxian Chen, Sijing Xia, Xiaojun Deng*, Qin Chen* and Bing Niu*
DOI: 10.2174/1573406415666191004142810

iATP: A Sequence Based Method for Identifying Anti-tubercular Peptides

Volume: 16   Issue: 5
Pp: 620-625
Wei Chen*, Pengmian Feng and Fulei Nie
DOI: 10.2174/1573406415666191002152441

Application of Machine Learning Methods in Predicting Nuclear Receptors and their Families

Volume: 16   Issue: 5
Pp: 594-604
Zi-Mei Zhang, Zheng-Xing Guan, Fang Wang, Dan Zhang and Hui Ding*
DOI: 10.2174/1573406415666191004125551