Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

Personal Subscription
Become EABM
Become Reviewer

Most Cited Article

USP7: Target Validation and Drug Discovery for Cancer Therapy

Volume:14   Issue:1
Pp: 3-18
Jin Zhou*, Jinzheng Wang, Chao Chen, Haoliang Yuan, Xiaoan Wen* and Hongbin Sun*
DOI: 10.2174/1573406413666171020115539

Synthesis and Structural Elucidation of Novel Benzothiazole Derivatives as Anti-tubercular Agents: In-silico Screening for Possible Target Identification

Volume:15   Issue:3
Pp: 311-326
Katharigatta N. Venugopala*, Sandeep Chandrashekharappa, Melendhran Pillay, Subhrajyoti Bhandary, Mahmoud Kandeel, Fawzi M. Mahomoodally, Mohamed A. Morsy, Deepak Chopra, Bandar E. Aldhubiab, Mahesh Attimarad, Osama I. Alwassil, Sree Harsha, Koleka Mlisana and Bharti Odhav
DOI: 10.2174/1573406414666180703121815

ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2

Volume:15   Issue:3
Pp: 277-286
Dina H. Dawood, Eman M.H. Abbas, Thoraya A. Farghaly*, Mamdouh M. Ali and Mohammed F. Ibrahim
DOI: 10.2174/1573406414666180912113226

Biology-Oriented Synthesis (BIOS) of Piperine Derivatives and their Comparative Analgesic and Antiinflammatory Activities

Volume:14   Issue:3
Pp: 269-280
Ammar Yasir, Saiqa Ishtiaq, Muhammad Jahangir, Muhammad Ajaib, Uzma Salar and Khalid M. Khan*
DOI: 10.2174/1573406413666170623083810

Is there a Link between Vitamin B and Multiple Sclerosis?

Volume:14   Issue:2
Pp: 170-180
Natalie Nemazannikova, Kathleen Mikkelsen, Lily Stojanovska, Gregory L. Blatch and Vasso Apostolopoulos*
DOI: 10.2174/1573406413666170906123857

New Perspectives of Alzheimer Disease Diagnosis – the Most Popular and Future Methods

Volume:14   Issue:1
Pp: 34-43
Katarzyna Pietrzak, Kamila Czarnecka, Elzbieta Mikiciuk-Olasik and Pawel Szymanski*
DOI: 10.2174/1573406413666171002120847

Helminthicidal and Larvicidal Potentials of Biogenic Silver Nanoparticles Synthesized from Medicinal Plant Momordica charantia

Volume:15   Issue:7
Pp: 781-789
Amruta Shelar, Jaiprakash Sangshetti, Shampa Chakraborti*, Ajay Vikram Singh*, Rajendra Patil* and Suresh Gosavi*
DOI: 10.2174/1573406415666190430142637

Synthesis, Characterization and Biological Activities of New Symmetric Bis-1,2,3-Triazoles with Click Chemistry

Volume:14   Issue:3
Pp: 230-241
Fatih Celik*, Yasemin Unver, Burak Barut, Arzu Ozel and Kemal Sancak
DOI: 10.2174/1573406413666171120165226

Cell Cycle Arrest and Apoptosis Induction Activity of Nitidine Chloride on Acute Myeloid Leukemia Cells

Volume:14   Issue:1
Pp: 60-66
Peng Li, Shuxin Yan, Xin Dong, Zhao Li, Yu Qiu, Chunyan Ji, Jingru Zhang, Min Ji, Wei Li, Hongchun Wang, Zhi Liu, Xing L. Wang, Jingjing Ye* and Daoxin Ma
DOI: 10.2174/1573406413666170620091543

New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities

Volume:15   Issue:1
Pp: 87-101
Uzma Salar, Khalid M. Khan*, Sridevi Chigurupati, Shazia Syed, Shantini Vijayabalan, Abdul Wadood, Muhammad Riaz, Mehreen Ghufran and Shahnaz Perveen
DOI: 10.2174/1573406414666180903162243

Thiazole Compounds as Antiviral Agents: An Update

Volume:16   Issue:1
Pp: 4-23
Inder P. Singh*, Shiv Gupta and Sanjay Kumar
DOI: 10.2174/1573406415666190614101253

The Inhibition of Polysialyltranseferase ST8SiaIV Through Heparin Binding to Polysialyltransferase Domain (PSTD)

Volume:15   Issue:5
Pp: 486-495
Li-Xin Peng, Xue-Hui Liu, Bo Lu, Si-Ming Liao, Feng Zhou, Ji-Min Huang, Dong Chen, Frederic A. Troy II, Guo-Ping Zhou* and Ri-Bo Huang*
DOI: 10.2174/1573406415666181218101623

In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?

Volume:14   Issue:3
Pp: 281-292
Ondrej Soukup, Jan Korabecny, David Malinak, Eugenie Nepovimova, Ngoc L. Pham, Kamil Musilek, Martina Hrabinova, Vendula Hepnarova, Rafael Dolezal, Petr Pavek, Petr Jost, Tereza Kobrlova, Jana Jankockova, Lukas Gorecki, Miroslav Psotka, Thuy D. Nguyen, Karl Box, Breeze Outhwaite, Martina Ceckova, Ales Sorf, Daniel Jun* and Kamil Kuca*
DOI: 10.2174/1573406414666180112105657

Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines

Volume:14   Issue:3
Pp: 293-303
Alexia Jonet, Jean Guillon, Catherine Mullie, Anita Cohen, Guillaume Bentzinger, Jeremy Schneider, Nicolas Taudon, Sebastien Hutter, Nadine Azas, Stephane Moreau, Solene Savrimoutou, Patrice Agnamey, Alexandra Dassonville-Klimpt and Pascal Sonnet*
DOI: 10.2174/1573406413666170726123938

Managing Neuropathic Pain in Multiple Sclerosis: Pharmacological Interventions

Volume:14   Issue:2
Pp: 106-119
Samuel S. Duffy, Justin G. Lees, Chamini J. Perera and Gila Moalem-Taylor*
DOI: 10.2174/1573406413666170906122508

Synthesis, Structure and Antiproliferative Activity of New pyrazolo[4,3- e]triazolo[4,5-b][1,2,4]triazine Derivatives

Volume:14   Issue:1
Pp: 53-59
Mariusz Mojzych*, Pawel Tarasiuk, Zbigniew Karczmarzyk, Malgorzata Juszczak, Wojciech Rzeski, Andrzej Fruzinski and Artur Wozny
DOI: 10.2174/1573406413666171020114924