Medicinal Chemistry

In vitro Synthesis, Structure Elucidation, and Antioxidant Properties of Platinum(IV)-hydrazide Complexes: Molecular Modeling of Free- Hydrazides Suggested as Potent Lipoxygenase Inhibitor

Rooma Badar, Uzma Ashiq *, Rifat Ara Jamal, Parveen Akhter, Mohammad Mahroof-Tahir, Sana Gul and Syed Tahir Ali

Novel Dipeptides Bearing Sulfonamide as Antimalarial and Antitrypanosomal Agents: Synthesis and Molecular Docking

Ogechi Chinelo Ekoh*, Uchechukwu Okoro, David Ugwu, Rafat Ali, Sunday Okafor, Daniel Ugwuja and Solomon Attah

Multi-target Directed Compounds with Antioxidant and/or Antiinflammatory Properties as Potent Agents for Alzheimer’s Disease

Georgios Papagiouvannis*, Panagiotis Theodosis-Nobelos, Panos N. Kourounakis and Eleni A. Rekka

Evaluation of Novel Substituted Furopyridines as Inhibitors of Protein Kinases Related to Tau Pathology in Alzheimer´s Disease

N. Schade, P. Koch, F. Ansideri, V. Krystof, M. Holzer and A. Hilgeroth*

Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes

Thiago M. de Aquino*, Paulo H. B. França, Érica E. E. S. Rodrigues, Igor J. S. Nascimento, Paulo F. S. Santos-Júnior, Pedro G. V. Aquino, Mariana S. Santos, Aline C. Queiroz, Morgana V. Araújo, Magna S. Alexandre-Moreira, Raiza R. L. Rodrigues, Klinger A. F. Rodrigues, Johnnatan D. Freitas, Jacques Bricard, Mario R. Meneghetti, Jean-Jacques Bourguignon, Martine Schmitt, Edeildo F. da Silva-Júnior* and João X. de Araújo-Júnior

Design, Synthesis and Evaluation of 2,4,6-substituted Pyrimidine Derivatives as BACE-1 inhibitor: Plausible lead for Alzheimer’s Disease

Priti Jain*, Pankaj K Wadhwa and Hemant R Jadhav

In vitro, in vivo and in silico Antihyperglycemic Activity of Some Semi-synthetic Phytol Derivatives

Harish C. Upadhyay, Akansha Mishra, Jyotsana Pandey, Pooja Sharma, Akhilesh K. Tamrakar, Arvind K. Srivastava, Feroz Khan and Santosh K. Srivastava*

A Combined Approach of Pharmacophore Modeling, QSAR Study, Molecular Docking and In silico ADME/Tox Prediction of 4-Arylthio & 4-Aryloxy-3- Iodopyridine-2(1H)-one Analogs to identify Potential Reverse Transcriptase Inhibitor: Anti-HIV Agents

Debadash Panigrahi*, Amiyakanta Mishra, Susanta Kumar Sahu, Mohd. Afzal Azam and C.M. Vyshaag

Synthesis of Some Novel Benzimidazole Derivatives as Anticancer Agent, and Evaluation for CDK2 Inhibition Activity

Rania Helmy Abd El-Hameed, Samar Said Fatahala* and Amira Ibrahim Sayed

Synthesis, Cytotoxicity, ADMET and Molecular Docking Studies of Some Quinoline-Pyrimidine Hybrid Compounds: 3-(2-Amino-6-arylpyrimidin-4- yl)-4-hydroxy-1-methylquinolin-2(1H)-ones

Duong Ngoc Toan*, Nguyen Dinh Thanh*, Mai Xuan Truong and Dinh Thuy Van