Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Most Cited Article

USP7: Target Validation and Drug Discovery for Cancer Therapy promotion: free to download

Volume:14   Issue:1
Pp: 3-18
Jin Zhou*, Jinzheng Wang, Chao Chen, Haoliang Yuan, Xiaoan Wen* and Hongbin Sun*
DOI: 10.2174/1573406413666171020115539

pLoc_bal-mVirus: Predict Subcellular Localization of Multi-Label Virus Proteins by Chou's General PseAAC and IHTS Treatment to Balance Training Dataset promotion: free to download

Volume:15   Issue:5
Pp: 496-509
Xuan Xiao*, Xiang Cheng, Genqiang Chen, Qi Mao and Kuo-Chen Chou
DOI: 10.2174/1573406415666181217114710

pLoc_bal-mEuk: Predict Subcellular Localization of Eukaryotic Proteins by General PseAAC and Quasi-balancing Training Dataset promotion: free to download

Volume:15   Issue:5
Pp: 472-485
Kuo-Chen Chou*, Xiang Cheng and Xuan Xiao
DOI: 10.2174/1573406415666181218102517

Synthesis and Structural Elucidation of Novel Benzothiazole Derivatives as Anti-tubercular Agents: In-silico Screening for Possible Target Identification promotion: free to download

Volume:15   Issue:3
Pp: 311-326
Katharigatta N. Venugopala*, Sandeep Chandrashekharappa, Melendhran Pillay, Subhrajyoti Bhandary, Mahmoud Kandeel, Fawzi M. Mahomoodally, Mohamed A. Morsy, Deepak Chopra, Bandar E. Aldhubiab, Mahesh Attimarad, Osama I. Alwassil, Sree Harsha, Koleka Mlisana and Bharti Odhav
DOI: 10.2174/1573406414666180703121815

ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2 promotion: free to download

Volume:15   Issue:3
Pp: 277-286
Dina H. Dawood, Eman M.H. Abbas, Thoraya A. Farghaly*, Mamdouh M. Ali and Mohammed F. Ibrahim
DOI: 10.2174/1573406414666180912113226

Synthesis of New Isoxazole-, Pyridazine-, Pyrimidopyrazines and Their Anti-Inflammatory and Analgesic Activity promotion: free to download

Volume:14   Issue:4
Pp: 356-371
Ameen A. Abu-Hashem* and Mohamed El-Shazly
DOI: 10.2174/1573406414666180112110947

Biology-Oriented Synthesis (BIOS) of Piperine Derivatives and their Comparative Analgesic and Antiinflammatory Activities promotion: free to download

Volume:14   Issue:3
Pp: 269-280
Ammar Yasir, Saiqa Ishtiaq, Muhammad Jahangir, Muhammad Ajaib, Uzma Salar and Khalid M. Khan*
DOI: 10.2174/1573406413666170623083810

Is there a Link between Vitamin B and Multiple Sclerosis? promotion: free to download

Volume:14   Issue:2
Pp: 170-180
Natalie Nemazannikova, Kathleen Mikkelsen, Lily Stojanovska, Gregory L. Blatch and Vasso Apostolopoulos*
DOI: 10.2174/1573406413666170906123857

New Perspectives of Alzheimer Disease Diagnosis – the Most Popular and Future Methods promotion: free to download

Volume:14   Issue:1
Pp: 34-43
Katarzyna Pietrzak, Kamila Czarnecka, Elzbieta Mikiciuk-Olasik and Pawel Szymanski*
DOI: 10.2174/1573406413666171002120847

Helminthicidal and Larvicidal Potentials of Biogenic Silver Nanoparticles Synthesized from Medicinal Plant Momordica charantia promotion: free to download

Volume:15   Issue:7
Pp: 781-789
Amruta Shelar, Jaiprakash Sangshetti, Shampa Chakraborti*, Ajay Vikram Singh*, Rajendra Patil* and Suresh Gosavi*
DOI: 10.2174/1573406415666190430142637

Synthesis, Characterization and Biological Activities of New Symmetric Bis-1,2,3-Triazoles with Click Chemistry promotion: free to download

Volume:14   Issue:3
Pp: 230-241
Fatih Celik*, Yasemin Unver, Burak Barut, Arzu Ozel and Kemal Sancak
DOI: 10.2174/1573406413666171120165226

Cell Cycle Arrest and Apoptosis Induction Activity of Nitidine Chloride on Acute Myeloid Leukemia Cells

Volume:14   Issue:1
Pp: 60-66
Peng Li, Shuxin Yan, Xin Dong, Zhao Li, Yu Qiu, Chunyan Ji, Jingru Zhang, Min Ji, Wei Li, Hongchun Wang, Zhi Liu, Xing L. Wang, Jingjing Ye* and Daoxin Ma
DOI: 10.2174/1573406413666170620091543

Novel Guanosine Derivatives as Anti-HCV NS5b Polymerase: A QSAR and Molecular Docking Study promotion: free to download

Volume:15   Issue:2
Pp: 130-137
Abdo A. Elfiky*
DOI: 10.2174/1573406414666181015152511

New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities promotion: free to download

Volume:15   Issue:1
Pp: 87-101
Uzma Salar, Khalid M. Khan*, Sridevi Chigurupati, Shazia Syed, Shantini Vijayabalan, Abdul Wadood, Muhammad Riaz, Mehreen Ghufran and Shahnaz Perveen
DOI: 10.2174/1573406414666180903162243

Myelin Oligodendrocyte Glycoprotein and Multiple Sclerosis

Volume:14   Issue:2
Pp: 120-128
Maria-Eleni Androutsou, Anthi Tapeinou, Alexios Vlamis-Gardikas* and Theodore Tselios*
DOI: 10.2174/1573406413666170906123204

Managing Neuropathic Pain in Multiple Sclerosis: Pharmacological Interventions

Volume:14   Issue:2
Pp: 106-119
Samuel S. Duffy, Justin G. Lees, Chamini J. Perera and Gila Moalem-Taylor*
DOI: 10.2174/1573406413666170906122508

Thiazole Compounds as Antiviral Agents: An Update

Volume:16   Issue:1
Pp: 4-23
Inder P. Singh*, Shiv Gupta and Sanjay Kumar
DOI: 10.2174/1573406415666190614101253

The Inhibition of Polysialyltranseferase ST8SiaIV Through Heparin Binding to Polysialyltransferase Domain (PSTD)

Volume:15   Issue:5
Pp: 486-495
Li-Xin Peng, Xue-Hui Liu, Bo Lu, Si-Ming Liao, Feng Zhou, Ji-Min Huang, Dong Chen, Frederic A. Troy II, Guo-Ping Zhou* and Ri-Bo Huang*
DOI: 10.2174/1573406415666181218101623

In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?

Volume:14   Issue:3
Pp: 281-292
Ondrej Soukup, Jan Korabecny, David Malinak, Eugenie Nepovimova, Ngoc L. Pham, Kamil Musilek, Martina Hrabinova, Vendula Hepnarova, Rafael Dolezal, Petr Pavek, Petr Jost, Tereza Kobrlova, Jana Jankockova, Lukas Gorecki, Miroslav Psotka, Thuy D. Nguyen, Karl Box, Breeze Outhwaite, Martina Ceckova, Ales Sorf, Daniel Jun* and Kamil Kuca*
DOI: 10.2174/1573406414666180112105657

Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines

Volume:14   Issue:3
Pp: 293-303
Alexia Jonet, Jean Guillon, Catherine Mullie, Anita Cohen, Guillaume Bentzinger, Jeremy Schneider, Nicolas Taudon, Sebastien Hutter, Nadine Azas, Stephane Moreau, Solene Savrimoutou, Patrice Agnamey, Alexandra Dassonville-Klimpt and Pascal Sonnet*
DOI: 10.2174/1573406413666170726123938