Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Most Cited Article

Thiazole Compounds as Antiviral Agents: An Update

Volume:16   Issue:1
Pp: 4-23
Inder P. Singh*, Shiv Gupta and Sanjay Kumar
DOI: 10.2174/1573406415666190614101253

iATP: A Sequence Based Method for Identifying Anti-tubercular Peptides

Volume:16   Issue:5
Pp: 620-625
Wei Chen*, Pengmian Feng and Fulei Nie
DOI: 10.2174/1573406415666191002152441

The Assessment of Interleukin-18 on the Risk of Coronary Heart Disease

Volume:16   Issue:5
Pp: 626-634
Weiju Sun, Ying Han, Shuo Yang, He Zhuang, Jingwen Zhang, Liang Cheng* and Lu Fu*
DOI: 10.2174/1573406415666191004115128

An Increasing Role of Polyphenols as Novel Therapeutics for Alzheimer’s: A Review

Volume:16   Issue:8
Pp: 1007-1021
Nasiara Karim, Haroon Khan*, Imran Khan, Ouyang Guo, Eduardo Sobarzo-Sánchez, Luca Rastrelli and Mohammad A. Kamal
DOI: 10.2174/1573406415666191105154407

Antiglycation Activity of Triazole Schiff’s Bases Against Fructosemediated Glycation: In Vitro and In Silico Study

Volume:16   Issue:4
Pp: 575-591
Muniza Shaikh, Salman Siddiqui, Humaira Zafar, Uzma Naqeeb, Fakiha Subzwari, Rehan Imad, Khalid M. Khan and Muhammad I. Choudhary*
DOI: 10.2174/1573406415666190212105718

Denouement of Chemicals on Amyotrophic Lateral Sclerosis: Is Green Chemistry the Answer

Volume:16   Issue:8
Pp: 1058-1068
Faizana Fayaz, Faheem H. Pottoo, Sadat Shafi, Mushtaq A. Wani, Sharad Wakode* and Anjali Sharma
DOI: 10.2174/1573406416666200413111330

Therapeutic Effects of Ziziphus jujuba Mill. Fruit in Traditional and Modern Medicine: A Review

Volume:16   Issue:8
Pp: 1069-1088
Zahra Sobhani , Sara Nikoofal-Sahlabadi, Mohammad S. Amiri, Mahin Ramezani, Seyed A. Emami* and Amirhossein Sahebkar*
DOI: 10.2174/1573406415666191031143553

Application of Machine Learning Methods in Predicting Nuclear Receptors and their Families

Volume:16   Issue:5
Pp: 594-604
Zi-Mei Zhang, Zheng-Xing Guan, Fang Wang, Dan Zhang and Hui Ding*
DOI: 10.2174/1573406415666191004125551

Recent Advances in Therapeutic Applications of Bisbenzimidazoles

Volume:16   Issue:4
Pp: 454-486
Smita Verma , Vishnuvardh Ravichandiran, Nihar Ranjan and Swaran J.S. Flora*
DOI: 10.2174/1573406415666190416120801

Prediction and Analysis of Hub Genes in Renal Cell Carcinoma based on CFS Gene Selection Method Combined with Adaboost Algorithm

Volume:16   Issue:5
Pp: 654-663
Yina Wang, Benrong Zheng, Manbin Xu, Shaoping Cai, Jeong Younseo, Chi Zhang* and Boxiong Jiang*
DOI: 10.2174/1573406415666191004100744

First Example of Antiparasitic Activity Influenced by Thermochromism: Leishmanicidal Evaluation of 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine Metal Complexes

Volume:16   Issue:3
Pp: 422-430
José M. Méndez-Arriaga*, Itziar Oyarzabal, Álvaro Martín-Montes, Judith García-Rodríguez, Miguel Quirós and Manuel Sánchez-Moreno
DOI: 10.2174/1573406415666190401120607

Inhibitors of Cyclin-Dependent Kinase 1/2 for Anticancer Treatment

Volume:16   Issue:3
Pp: 307-325
Jiajia Mou*, Danghui Chen and Yanru Deng
DOI: 10.2174/1573406415666190626113900

Synthesis of β-Ketosulfone Derivatives As New Non-Cytotoxic Urease Inhibitors In Vitro

Volume:16   Issue:2
Pp: 244-255
Sarosh Iqbal*, Ajmal Khan, Rashid Nazir, Shumaila Kiran, Shahnaz Perveen, Khalid M. Khan* and Muhammad I. Choudhary*
DOI: 10.2174/1573406415666190415163309

Novel p-Functionalized Chromen-4-on-3-yl Chalcones Bearing Astonishing Boronic Acid Moiety as MDM2 Inhibitor: Synthesis, Cytotoxic Evaluation and Simulation Studies

Volume:16   Issue:2
Pp: 212-228
Richa K. Bhatia*, Lakhwinder Singh, Ruchika Garg, Maninder Kaur, Manmohan Yadav, Jitender Madan, Satyavathi Kancherla, Raghuvir R.S. Pissurlenkar and Evans C. Coutinho
DOI: 10.2174/1573406415666190531123751

Benzoylthioureas: Design, Synthesis and Antimycobacterial Evaluation

Volume:16   Issue:1
Pp: 93-103
Tiago O. Brito, Lethícia O. Abreu, Karen M. Gomes, Maria C.S. Lourenço, Patricia M.L. Pereira, Sueli F. Yamada-Ogatta, Ângelo de Fátima, Cesar A. Tisher, Fernando Macedo Jr and Marcelle L.F. Bispo*
DOI: 10.2174/1573406415666181208110753

Design and Synthesis of Novel Sulfonamide-Derived Triazoles and Bioactivity Exploration

Volume:16   Issue:1
Pp: 104-118
Shi-Chao He, Hui-Zhen Zhang*, Hai-Juan Zhang, Qing Sun and Cheng-He Zhou*
DOI: 10.2174/1573406414666181106124852

Tyramine Derivatives as Potent Therapeutics for Type 2 Diabetes: Synthesis and In Vitro Inhibition of α-Glucosidase Enzyme

Volume:16   Issue:8
Pp: 1124-1135
Muhammad A. Bashir, Kulsoom Javaid, Muniza Shaikh, Muhammad I. Choudhary* and Hina Siddiqui*
DOI: 10.2174/1573406416666200128114422

Herbal Medicine for Glioblastoma: Current and Future Prospects

Volume:16   Issue:8
Pp: 1022-1043
Imran Khan, Sadaf Mahfooz and Mustafa A. Hatiboglu*
DOI: 10.2174/1573406416666200130100833

Synthesis, Anticancer Activity on Prostate Cancer Cell Lines and Molecular Modeling Studies of Flurbiprofen-Thioether Derivatives as Potential Target of MetAP (Type II)

Volume:16   Issue:6
Pp: 735-749
Özgür Yılmaz, Burak Bayer, Hatice Bekçi, Abdullahi I. Uba, Ahmet Cumaoğlu, Kemal Yelekçi and Ş. Güniz Küçükgüzel*
DOI: 10.2174/1573406415666190613162322