Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Volume:9   Issue: 3
Pp: i-vi

DOI: 10.2174/1573406411309030001

Structural and Molecular Docking Studies of 4-Benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one with Anticancer Activity

Volume:9   Issue: 3
Pp: 313-328
Agnieszka A. Kaczor, Monika Pitucha, Zbigniew Karczmarzyk, Waldemar Wysocki, Jolanta Rzymowska and Dariusz Matosiuk
DOI: 10.2174/1573406411309030002

Synthesis, Topoisomerase I Inhibitory and Cytotoxic Activities of Chromone Derivatives

Volume:9   Issue: 3
Pp: 329-339
Chirattikan Maicheen, Jiraphun Jittikoon, Opa Vajragupta and Jiraporn Ungwitayatorn
DOI: 10.2174/1573406411309030003

Design, Synthesis, and In vitro Antitumor Evaluation of Novel Phenylaminopyrimidine Derivatives

Volume:9   Issue: 3
Pp: 340-350
Youguang Zheng, Ming Zheng, Yi Liu, Yunsheng Xue, Ling Zhang, Lin An, Ling Liu and Min Ji
DOI: 10.2174/1573406411309030004

Synthesis, Cytotoxicity, Antibacterial and Antileishmanial Activities of Imidazolidine and Hexahydropyrimidine Derivatives

Volume:9   Issue: 3
Pp: 351-359
Gustavo S. G. de Carvalho, Rafael M. P. Dias, Fernando R. Pavan, Clarice Q. F. Leite, Vania L. Silva, Claudio G. Diniz, Daniela T. S. de Paula, Elaine S. Coimbra, Pascal Retailleau and Adilson D. da Silva
DOI: 10.2174/1573406411309030005

Synthesis, Molecular Docking and Antiamnesic Activity of Selected 2- Naphthyloxy Derivatives

Volume:9   Issue: 3
Pp: 371-378
Poonam Piplani, Paramveer Singh and Anuradha Sharma
DOI: 10.2174/1573406411309030007

Synthesis and Antimalarial Activity Study of Some New Mannich Bases of 7-Chloro-4-Aminoquinoline

Volume:9   Issue: 3
Pp: 379-383
Susanta Roy, Dipak Chetia, Mithun Rudrapal and Anil Prakash
DOI: 10.2174/1573406411309030008

Synthesis, Antifungal Activity, and Molecular Docking Studies of Novel Triazole Derivatives

Volume:9   Issue: 3
Pp: 384-388
Nan Wang, Xiaoyun Chai, Ying Chen, Lei Zhang, Wenjuan Li, Yijun Gao, Yi Bi, Shichong Yu and Qingguo Meng
DOI: 10.2174/1573406411309030009

CoMFA and CoMSIA 3D QSAR Models for a Series of Some Condensed Thieno[2,3-d]pyrimidin-4(3H)-ones with Antihistaminic (H1) Activity

Volume:9   Issue: 3
Pp: 389-401
Meenakshi Singh, Sushil K. Singh, Mahesh T. Chhabria, Kamala Vasu and Dhaivat Pandya
DOI: 10.2174/1573406411309030010

Modeling of LIM-Kinase 2 Inhibitory Activity of Pyrrolopyrimidine Analogues: Useful in Treatment of Ocular Hypertension and Glaucoma

Volume:9   Issue: 3
Pp: 402-409
Gagandip Singh, Manish K. Gupta, Viney Kumar and Yenamandra S. Prabhakar
DOI: 10.2174/1573406411309030011

Quantitative Structure-Activity Relationship Study of Aromatic Inhibitors Against Rat Lens Aldose Reductase Activity Using Variable Selections

Volume:9   Issue: 3
Pp: 410-419
Mankil Jung, Yongnam Lee, Minjoo Shim, Eunyoung Lim, Eun Jig Lee and Hyun Chul Lee
DOI: 10.2174/1573406411309030012

Quantitative Structure-activity Relationships of Imidazole-containing Farnesyltransferase Inhibitors Using Different Chemometric Methods

Volume:9   Issue: 3
Pp: 434-448
Ali Shayanfar, Saeed Ghasemi, Somaieh Soltani, Karim Asadpour-Zeynali, Robert J. Doerksen and Abolghasem Jouyban
DOI: 10.2174/1573406411309030014

Synthesis, Antifungal Evaluation and Molecular Docking Studies on 2- thioxoimidazolidin-4-one Derivatives

Volume:9   Issue: 3
Pp: 459-473
Sudha Vengurlekar, Rajesh Sharma and Piyush Trivedi
DOI: 10.2174/1573406411309030016