Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume: 9 Issue: 1, February 2012



Graphical Abstracts

Volume:9   Issue: 1
Pp: i-vi

DOI: 10.2174/157340641130901000i
Published on: 29 November, 2012

Foreword

Volume:9   Issue: 1
Pp: vii-vii
Atta-ur-Rahman
DOI: 10.2174/1573406411309010vii
Published on: 29 November, 2012

Synthesis and Opioid Activity of Novel 6-ketolevorphanol Derivatives

Volume:9   Issue: 1
Pp: 1-10
Zsuzsanna Gyulai, Antal Udvardy, Attila Cs. Bényei, Jakub Fichna, Katarzyna Gach, Martin Storr, Géza Tóth, Sándor Antus, Sándor Berényi, Anna Janecka and Attila Siposa
DOI: 10.2174/1573406411309010001
Published on: 29 November, 2012

Syntheses, DNA Binding and Anticancer Profiles of L-Glutamic Acid Ligand and its Copper(II) and Ruthenium(III) Complexes

Volume:9   Issue: 1
Pp: 11-21
Imran Ali, Waseem A. Wani, Kishwar Saleem and Diana Wesselinova
DOI: 10.2174/1573406411309010011
Published on: 29 November, 2012

Identification of Structural and Electronic Features for a Series of MCH1R Antagonists

Volume:9   Issue: 1
Pp: 22-31
Danielle C. Silva, Adriano D. Andricopulo, Emmanuela F. de Lima and Káthia M. Honório
DOI: 10.2174/1573406411309010022
Published on: 29 November, 2012

Predicting the Activity of Antimicrobial Peptides with Amino Acid Topological Information

Volume:9   Issue: 1
Pp: 32-44
Mao Shu, Rui Yu, Yunru Zhang, Juan Wang, Li Yang, Li Wang and Zhihua Lin
DOI: 10.2174/1573406411309010032
Published on: 29 November, 2012

Design, Synthesis and Antimicrobial Properties of Novel 3,3a,4,5,6,7- Hexahydroindazole and Arylthiazolylpyrazoline Derivatives

Volume:9   Issue: 1
Pp: 45-52
Abha Bishnoi, Suruchi Singh, Anil K. Tiwari, Arun Sethi and Chandrakant Mani Tripathi
DOI: 10.2174/1573406411309010045
Published on: 29 November, 2012

Synthesis, Antimycobacterial, Antiviral, Antimicrobial Activity and QSAR Studies of N2-acyl isonicotinic Acid Hydrazide Derivatives

Volume:9   Issue: 1
Pp: 53-76
Vikramjeet Judge, Balasubramanian Narasimhan, Munish Ahuja, Dharmarajan Sriram, Perumal Yogeeswari, Erik De Clercq, Christophe Pannecouque and Jan Balzarini
DOI: 10.2174/1573406411309010053
Published on: 29 November, 2012

Novel 2-hydrazino-pyrimidin-4(3H)-one Derivatives with Pseudofunctional- Similarity to Siderophores as Potential Antimycobacterial Agents

Volume:9   Issue: 1
Pp: 77-83
Ranjeet Bairwa, Nilesh R. Tawari, Amruta Alate, Swapnil Anam, Mariam S. Degani, Muktikant Ray and Ramakrishna M. G. Rajan
DOI: 10.2174/1573406411309010077
Published on: 29 November, 2012

5-Arylidene-4-Thiazolidinone Derivatives Active as Antidegenerative Agents on Human Chondrocyte Cultures

Volume:9   Issue: 1
Pp: 84-90
Annamaria Panico, Rosanna Maccari, Venera Cardile, Lucia Crascì, Simone Ronsisvalle and Rosaria Ottanà
DOI: 10.2174/1573406411309010084
Published on: 29 November, 2012

Synthesis, p38 Kinase Inhibitory and Anti-inflammatory Activity of New Substituted Benzimidazole Derivatives

Volume:9   Issue: 1
Pp: 91-99
Ravindra G. Kulkarnia, Stefan A. Laufer, Chandrashekhar V. M and Achaiah Garlapati
DOI: 10.2174/1573406411309010091
Published on: 29 November, 2012

Novel C-9, 9'-O-acyl Esters of (-)-Carinol as Free-radical Scavengers and Xanthine Oxidase Enzyme Inhibitors: Synthesis and Biological Evaluation

Volume:9   Issue: 1
Pp: 100-103
Praveen Kumar Suryadevara, Hari Babu Tatipaka, Rama Subba Rao Vidadala, Ashok k Tiwari, Janaswamy Madhusudana Rao and Katragadda Suresh Babu
DOI: 10.2174/1573406411309010100
Published on: 29 November, 2012

Design, Synthesis and In-vivo Hypoglycemic Evaluation of Novel Non - TZD’S in a Type - 2 Diabetic Model

Volume:9   Issue: 1
Pp: 104-111
Rupali Jadhav, Ranu Gupta-Rajoria, Tanushree Pal and Ramaa Chelakara Subramanian
DOI: 10.2174/1573406411309010104
Published on: 29 November, 2012

Synthesis and In-vitro Photodynamic Studies of the Superparamagnetic Chitosan Hydrogel/Chlorin E6 Nanocarriers

Volume:9   Issue: 1
Pp: 112-117
Mohammad Reza Saboktakin, Roya M. Tabatabaie, Fahimeh Satarzade Amini, Abel Maharramov and Mohammad Ali Ramazanov
DOI: 10.2174/1573406411309010112
Published on: 29 November, 2012

Synthesis and Biological Evaluation of Novel Pentacyclic Triterpene Derivatives as Potential PPARγ Agonists

Volume:9   Issue: 1
Pp: 118-125
Liying Zhang, Jizhe Dong, Jun Liu, Luyong Zhang, Lingyi Kong, Hequan Yao and Hongbin Sun
DOI: 10.2174/1573406411309010118
Published on: 29 November, 2012

Discovering the Binding Modes of Natural Products with Histone Deacetylase 1

Volume:9   Issue: 1
Pp: 126-132
Lei Zhang, Minyong Li, Lihui Zhang and Wenfang Xu
DOI: 10.2174/1573406411309010126
Published on: 29 November, 2012

Prediction of Allergenic Proteins by Means of the Concept of Chou’s Pseudo Amino Acid Composition and a Machine Learning Approach

Volume:9   Issue: 1
Pp: 133-137
Hassan Mohabatkara, Majid Mohammad Beigib, Kolsoum Abdolahic and Sasan Mohsenzadeh
DOI: 10.2174/1573406411309010133
Published on: 29 November, 2012

Exploring the Biological Potential of Urea Derivatives Against mPGES-1: A Combination of Quantum Mechanics, Pharmacophore Modelling and QSAR Analyses

Volume:9   Issue: 1
Pp: 138-151
Malkeet Singh Bahia and Om Silakari
DOI: 10.2174/1573406411309010138
Published on: 29 November, 2012

QSAR and Pharmacophore Study of Dyrk1A Inhibitory Meridianin Analogs as Potential Agents for Treatment of Neurodegenerative Diseases

Volume:9   Issue: 1
Pp: 152-161
Sandip B. Bharate, Rammohan R. Yadav and Ram A. Vishwakarma
DOI: 10.2174/1573406411309010152
Published on: 29 November, 2012