Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

Personal Subscription
Become EABM
Become Reviewer

Novel Gastrin Receptor-Directed Contrast Agents - Potential in Brain Tumor Magnetic Resonance Imaging

Volume:8   Issue: 2
Pp: 133-137
Alexander Sturzu, Sumbla Sheikh, Uwe Klose, Martin Deeg, Hartmut Echner, Thomas Nagele, Ulrike Ernemann and Stefan Heckl
DOI: 10.2174/157340612800493566

Facile Synthesis and Biological Evaluation of Novel Symmetrical Biphenyls as Antitumor Agents

Volume:8   Issue: 2
Pp: 145-150
Jie Zhang, Yanmin Zhang, Xiaoyan Pan, Chen Wang, Zhigang Hu, Sicen Wang and Langchong He
DOI: 10.2174/157340612800493656

Synthesis and Anticancer Activity of Novel Benzimidazole and Benzothiazole Derivatives against HepG2 Liver Cancer Cells

Volume:8   Issue: 2
Pp: 151-162
Amal M. Youssef, Ahmed Malki, Mona H. Badr, Rasha Y. Elbayaa and Ahmed S. Sultan
DOI: 10.2174/157340612800493719

Synthesis and Cytotoxic Evaluation of Quinazolin-4(3H)-one Derivatives Bearing Thiocarbamate, Thiourea or N-Methyldithiocarbamate Side Chains

Volume:8   Issue: 2
Pp: 163-173
Sheng-Li Cao, Hong Xu, Yao Wang, Ji Liao, Jing-Jing Zhang, Zhong-Feng Li, Yan-Wen Guo, Xiao-Rong Li, Xue-Mei Cui and Xingzhi Xu
DOI: 10.2174/157340612800493665

Optimization of Important Early ADME(T) Parameters of NADPH Oxidase-4 Inhibitor Molecules

Volume:8   Issue: 2
Pp: 174-181
Gabor Borbely, Monika Huszar, Attila Varga, Krisztina Futosi, Attila Mocsai, Laszlo Orfi, Miklos Idei, Jozsef Mandl, Gyorgy Keri and Tibor Vantus
DOI: 10.2174/157340612800493674

Design, Synthesis & Biological Evaluation of Some Novel Quinazolinone Scaffolds

Volume:8   Issue: 2
Pp: 182-192
Rahul P. Modh, Amit C. Patel and Kishor H. Chikhalia
DOI: 10.2174/157340612800493610

A Pharmacophore Model Specific to Active Site of CYP1A2 with a Novel Molecular Modeling Explorer and CoMFA

Volume:8   Issue: 2
Pp: 198-207
Hitesh K. Agarwal, Gustavo F. Doncel and Keykavous Parang
DOI: 10.2174/157340612800493601

Molecular Dynamics Simulations of CYP2E1

Volume:8   Issue: 2
Pp: 208-221
Jue Li, Dong-Qing Wei, Jing-Fang Wang, Zheng-Tian Yu and Kuo-Chen Chou
DOI: 10.2174/157340612800493692

Synthesis of a Fluorescently Labeled Compound for the Detection of Arsenic-induced Apoptotic HL60 Cells

Volume:8   Issue: 2
Pp: 222-229
A. Lis Femia, C. Facundo Temprana, M. Silvia Amor, Mariano Grasselli and Silvia del V. Alonso
DOI: 10.2174/157340612800493584

An In Silico Stereo-electronic Comparison of Conventional Pyridinium Oximes and K-oximes for Organophosphate (OP) Poisoning

Volume:8   Issue: 2
Pp: 230-245
Apurba K. Bhattacharjee, Kamil Kuca, Kamil Musilek and Richard K. Gordon
DOI: 10.2174/157340612800493700

Synthesis and Study the Analgesic Effects of New Analogues of Ketamine on Female Wistar Rats

Volume:8   Issue: 2
Pp: 246-251
Abbas Ahmadi, Mohsen Khalili, Ramin Hajikhani, Horiesadat Hosseini, Nasrin Afshin and Babak Nahri-Niknafs
DOI: 10.2174/157340612800493683

2D Chemometrics Analyses of Tetrahydroquinoline and Ethylenediamine Derivatives with Antimalarial Activity

Volume:8   Issue: 2
Pp: 252-265
Humberto Fonseca de Freitas and Marcelo Santos Castilho
DOI: 10.2174/157340612800493575

Synthesis and In Vivo Antimalarial Evaluation of Novel Hydroxyethylamine Derivatives

Volume:8   Issue: 2
Pp: 266-272
Mariana Conceicao de Souza, Triciana Goncalves-Silva, Marcele Moreth, Claudia R.B. Gomes, Carlos Roland Kaiser, Maria das Gracas Muller de Oliveira Henriques and Marcus V.N. de Souza
DOI: 10.2174/157340612800493638

Small Molecule Hydrazide Agents to Inhibit Growth and Proliferation of Mycobacterium Tuberculosis

Volume:8   Issue: 2
Pp: 273-280
Ronald Bartzatt, Suat L.G. Cirillo and Jeffrey D. Cirillo
DOI: 10.2174/157340612800493647

Structure-Activity Relationships of 2-Benzylsulfanylbenzothiazoles: Synthesis and Selective Antimycobacterial Properties

Volume:8   Issue: 2
Pp: 281-292
Vera Klimesova, Jan Koci, Karel Palat, Jirina Stolarikova, Hans-Martin Dahse and Ute Mollmann
DOI: 10.2174/157340612800493593

Synthesis and Preliminary Antihyperlipidaemic Activities Evaluation of Andrographolide Derivatives

Volume:8   Issue: 2
Pp: 293-298
Bin Wang, Chunlei Tang, Yaodan Han, Ruzhou Guo, Hai Qian and Wenlong Huang
DOI: 10.2174/157340612800493629