Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Volume: 7 Issue: 1, January

Studies on Synthesis, Activity and Binding with DNA of a New Trinuclear Platinum Compound [{trans-PtCl(NH3)2}2{trans-Pt(thiazole)2}{H2N(CH2)6 NH2}2]Cl3(NO3)

Volume:7   Issue: 1
Pp: 1-8
Jehad Al-Shuneigat, Yu Qing, Philip Beale, Keith Fisher and Fazlul Huq
DOI: 10.2174/157340611794072652
Published on: 01 March, 2012

N-Valproyl-L-Tryptophan for CNS-Targeting: Synthesis, Characterization and Efficacy In Vitro Studies of a New Potential Antiepileptic Drug

Volume:7   Issue: 1
Pp: 9-17
Viviana De Caro, Giulia Giandalia, Maria Gabriella Siragusa, Liliana Lamartina, Simonetta Friscia, Pierangelo Sardo, Fabio Carletti, Valerio Rizzo, Giuseppe Ferraro and Libero Italo Giannola
DOI: 10.2174/157340611794072733
Published on: 01 March, 2012

Design, Synthesis and Preliminary Evaluation of Novel Imperatorin Derivatives as Vasorelaxant Agents

Volume:7   Issue: 1
Pp: 18-23
Na Li, Jianyu He, Yingzhuan Zhan, Nan Zhou and Jie Zhang
DOI: 10.2174/157340611794072715
Published on: 01 March, 2012

Docking and Molecular Dynamics Study on the Inhibitory Activity of Novel Inhibitors on Epidermal Growth Factor Receptor (EGFR)

Volume:7   Issue: 1
Pp: 24-31
Qing-Hua Liao, Qing-Zhi Gao, Jing Wei and Kuo-Chen Chou
DOI: 10.2174/157340611794072698
Published on: 01 March, 2012

LYP3, a New Bestatin Derivative for Aminopeptidase N Inhibition

Volume:7   Issue: 1
Pp: 32-36
Yepeng Luan, Chunhua Ma, Zhongguo Sui, Xuejian Wang, Jinhong Feng, Ning Liu, Fanbo Jing, Yan Wang, Minyong Li, Hao Fang and Wenfang Xu
DOI: 10.2174/157340611794072706
Published on: 01 March, 2012

Effects of Quinone Derivatives, such as 1,4-Naphthoquinone, on DNA Polymerase Inhibition and Anti-Inflammatory Action

Volume:7   Issue: 1
Pp: 37-44
Kazuki Kobayashi, Shin Nishiumi, Masayuki Nishida, Midori Hirai, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina and Masaru Yoshida
DOI: 10.2174/157340611794072742
Published on: 01 March, 2012

The Effect of Systematic Structural Modifications on the Antibacterial Activity of Novel Oxazolidinones

Volume:7   Issue: 1
Pp: 45-55
Gabor Pinter, Ilona Bereczki, Elizabeth Roth, Attila Sipos, Reny Varghese, Edet Ekpenyong Udo, Eszter Ostorhazi, Ferenc Rozgonyi, Oludotun Adebayo Phillips and Pal Herczegh
DOI: 10.2174/157340611794072670
Published on: 01 March, 2012

Menthone Aryl Acid Hydrazones: A New Class of Anticonvulsants

Volume:7   Issue: 1
Pp: 56-61
Jainendra Jain, Y. Kumar, Reema Sinha, Rajeev Kumar and James Stables
DOI: 10.2174/157340611794072689
Published on: 01 March, 2012

Reversal of Cardiac Iron Loading and Dysfunction in Thalassemic Mice by Curcuminoids

Volume:7   Issue: 1
Pp: 62-69
C. Thephinlap, C. Phisalaphong, N. Lailerd, N. Chattipakorn, P. Winichagoon, J. Vadolas, S. Fucharoen, J.B. Porter and S. Srichairatanakool
DOI: 10.2174/157340611794072724
Published on: 01 March, 2012

Retraction Notice: Synthesis and Pharmacological Activity of Potential Cocaine Antagonists. 2. Structure-Activity Relationship Studies of Piperidine Ring-Substituted Methylphenidate Analogs free to download

Volume:7   Issue: 1
Pp: 70-70
Babatunde Ojo and Bejoy K . Chowdhury
DOI: 10.2174/157340611794072661
Published on: 01 March, 2012