Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Controlled Exploration of Structural Databases: The Case of Farnesyl Transferase Inhibitors

Volume:5   Issue: 3
Pp: 208-215
A. Tizot, G. C. Tucker, A. Pierre, J. Hickman and S. Goldstein
DOI: 10.2174/157340609788185891

Polyamide Curvature and DNA Sequence Selective Recognition: Use of 4-Aminobenzamide to Adjust Curvature

Volume:5   Issue: 3
Pp: 216-226
Jamie Lajiness, Alan Sielaff, Hilary Mackay, Toni Brown, Jerome Kluza, Binh Nguyen, W. David Wilson, Moses Lee and John A. Hartley
DOI: 10.2174/157340609788185945

Synthesis and In Vitro Anti-Lung Cancer Activity of Novel 1, 3, 4, 8- Tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-o ne Alkaloid Analogs

Volume:5   Issue: 3
Pp: 227-236
Dwayaja H. Nadkarni, Feng Wang, Wei Wang, Elizabeth R. Rayburn, Scharri J. Ezell, Srinivasan Murugesan, Sadanandan E. Velu and Ruiwen Zhang
DOI: 10.2174/157340609788185873

Analysis of Pralidoxime in Serum, Brain and CSF of Rats

Volume:5   Issue: 3
Pp: 237-241
Huba Kalasz, Eva Szoko, Tamas Tabi, Georg A. Petroianu, Dietrich E. Lorke, Abdulrab Omar, Salem Alafifi, Almerri Jasem and Kornelia Tekes
DOI: 10.2174/157340609788185882

Binding Mechanism of H5N1 Influenza Virus Neuraminidase with Ligands and its Implication for Drug Design

Volume:5   Issue: 3
Pp: 242-249
Ke Gong, Lin Li, Jing-Fang Wang, Feng Cheng, Dong-Qing Wei and Kuo-Chen Chou
DOI: 10.2174/157340609788185936

Possible Drug Candidates for Alzheimers Disease Deduced from Studying their Binding Interactions with α7 Nicotinic Acetylcholine Receptor

Volume:5   Issue: 3
Pp: 250-262
Ruo-Xu Gu, Hui Gu, Zhi-Yuan Xie, Jing-Fang Wang, Hugo R. Arias, Dong-Qing Wei and Kuo-Chen Chou
DOI: 10.2174/157340609788185909

Binding of CYP2C9 with Diverse Drugs and its Implications for Metabolic Mechanism

Volume:5   Issue: 3
Pp: 263-270
Jing-Fang Wang, Jing-Yi Yan, Dong-Qing Wei and Kuo-Chen Chou
DOI: 10.2174/157340609788185954

Structure-Activity Relationships for Serotonin Transporter and Dopamine Receptor Selectivity

Volume:5   Issue: 3
Pp: 271-278
Snezana Agatonovic-Kustrin, Paul Davies and Joseph V. Turner
DOI: 10.2174/157340609788185927

Synthesis, Structural Characterization and Antibacterial Activity of Novel 7β-{[3-(substituted phenyl)-2-propenoyl]amino}-3-[(2,5-dihydro-6-hydroxy- 2-methyl)-5-oxo-cis-triazin-3-yl]-thiomethyl-cefalosporins

Volume:5   Issue: 3
Pp: 283-292
Zalua Rodriguez, Miguel A. Lopez, Maritza Gonzalez, Blanca Tolon, Loreta Nadal, Leonora Gonzalez, Herman Velez and Adamo Fini
DOI: 10.2174/157340609788185855

Synthesis and Comparison of Antimalarial Activity of Febrifugine Derivatives Including Halofuginone

Volume:5   Issue: 3
Pp: 293-300
Bhupesh S. Samant and Mugdha G. Sukhthankar
DOI: 10.2174/157340609788185846