Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume: 4 Issue: 1, January

Synthesis and Pharmacological Evaluation of 4-Phenoxy-1,2,3,4- Tetrahydroisoquinolines and 4,5,6,6a-Tetrahydrochromeno [2,3,4-de]isoquinolines open Access plus

Volume:4   Issue: 1
Pp: 1-10
G. Giorgioni, S. Ruggieri, F. Claudi, A. Di Stefano, E. Ljung and T. Carlsson
DOI: 10.2174/157340608783331506
Published on: 01 March, 2012

Insight into the Bioreductive Mode of Action of Antitrypanosomal 5- Nitrofuryl Containing Thiosemicarbazones open Access plus

Volume:4   Issue: 1
Pp: 11-17
D. Gambino, L. Otero, J. D. Maya, A. Morello, C. Rigol, G. Barriga, J. Rodriguez, C. Folch, E. Norambuena, M. Gonzalez, C. Olea Azar and H. Cerecetto
DOI: 10.2174/157340608783331470
Published on: 01 March, 2012

Synthesis, Molecular Docking and PTP1B Inhibitory Activity of Functionalized 4,5-Dihydronaphthofurans and Dibenzofurans open Access plus

Volume:4   Issue: 1
Pp: 18-24
Atul Goel, Manish Dixit, Uzma Saeed, Amit Kumar, Mohammad Imran Siddiqi, Akhilesh K. Tamrakar and Arvind K. Srivastava
DOI: 10.2174/157340608783331515
Published on: 01 March, 2012

Synthesis and Theoretical Calculations of 5-Aminosalicylic Acid Derivatives as Potential Analgesic Agents open Access plus

Volume:4   Issue: 1
Pp: 25-29
Trujillo-Ferrara Jose, Correa-Basurto Jose, M. C. Rosales-Hernandez, Ramirez-San Juan Eduardo, Badillo Abigail, Z. Gomez-Castro Carlos and L. H. Fabila-Castillo
DOI: 10.2174/157340608783331489
Published on: 01 March, 2012

Estimation of Human Carbonic Anhydrase II Inhibition Using Topological Indices and their Combination with Quantum-Theoretical Descriptors open Access plus

Volume:4   Issue: 1
Pp: 30-66
Padmakar V. Khadikar, Jyoti Singh, Shalini Singh, Rajika Mishra, Claudiu T. Supuran, Brian W. Clare and Meenakshi Lakhwani
DOI: 10.2174/157340608783331461
Published on: 01 March, 2012

Studies on the Structure-Activity Relationship of the Basic Amine of Phenylpiperazines as Melanocortin-4 Receptor Antagonists open Access plus

Volume:4   Issue: 1
Pp: 67-74
Chen Chen, Joe A. Tran, Melissa Arellano, Beth A. Fleck, Joseph Pontillo, Dragan Marinkovic, Fabio C. Tucci, Jenny Wen and John Saunders
DOI: 10.2174/157340608783331498
Published on: 01 March, 2012

HIV Protease Inhibitors Impact on Apoptosis open Access plus

Volume:4   Issue: 1
Pp: 75-79
Stacey A. Rizza and Andrew D. Badley
DOI: 10.2174/157340608783331443
Published on: 01 March, 2012

Simulation of Sequential Screening Experiments Using Emerging Chemical Patterns open Access plus

Volume:4   Issue: 1
Pp: 80-90
Jurgen Bajorath and Jens Auer
DOI: 10.2174/157340608783331452
Published on: 01 March, 2012