Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Synthesis and Biological Evaluation of 2-amino-3-(3, 4, 5-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a New Class of Antitubulin Agents

Volume:3   Issue: 6
Pp: 507-512
Romeo Romagnoli, Pier Giovanni Baraldi, Vincent Remusat, Maria Dora Carrion, Carlota Lopez Cara, Olga Cruz-Lopez, Delia Preti, Francesca Fruttarolo, Mojgan Aghazadeh Tabrizi, Jan Balzarini and Ernest Hamel
DOI: 10.2174/157340607782360380

Design, Synthesis and Biological Evaluation of a Series of Thioamides as Non-Nucleoside Reverse Transcriptase Inhibitors

Volume:3   Issue: 6
Pp: 513-519
Ahmed S. Mehanna, Jitendra D. Belani, Charles J. Kelley and Luke A. Pallansch
DOI: 10.2174/157340607782360344

Synthesis and Anti-Picornaviridae In Vitro Activity of a New Class of Helicase Inhibitors the N,N-bis[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl] alkyldicarboxamides

Volume:3   Issue: 6
Pp: 520-532
A. Carta, M. Loriga, S. Piras, G. Paglietti, M. Ferrone, M. Fermeglia, S. Pricl, P. La Colla, G. Collu, T. Sanna and R. Loddo
DOI: 10.2174/157340607782360308

Design, Synthesis and Pharmacological Evaluation of HIV-1 Reverse Transcriptase Inhibition of New Indolin-2-Ones

Volume:3   Issue: 6
Pp: 533-542
Nubia Boechat, W. Bruce Kover, Vera Bongertz, Monica M. Bastos, Nelilma C. Romeiro, Maria L.G. Azevedo and Wagner Wollinger
DOI: 10.2174/157340607782360326

The Preparation and Human Muscarinic Receptor Profiling of Oxybutynin and N-Desethyloxybutynin Enantiomers

Volume:3   Issue: 6
Pp: 543-545
Allen B. Reitz, Suneel K. Gupta, Yifang Huang, Michael H. Parker and Richard R. Ryan
DOI: 10.2174/157340607782360353

A Salicylic Acid-Based Analogue Discovered from Virtual Screening as a Potent Inhibitor of Human 20α-Hydroxysteroid Dehydrogenase

Volume:3   Issue: 6
Pp: 546-550
Urmi Dhagat, Vincenzo Carbone, Roland P.-T. Chung, Toshihiro Matsunaga, Satoshi Endo, Akira Hara and Ossama El-Kabbani
DOI: 10.2174/157340607782360399

Synthesis of 1,2,4-triazole Derivatives: Binding Properties on Endothelin Receptors

Volume:3   Issue: 6
Pp: 551-560
L. Salerno, F. Guerrera, M. Modica, G. Romeo, V. Pittala, M. A. Siracusa, I. Mereghetti, A. Cagnotto and T. Mennini
DOI: 10.2174/157340607782360281

Design and Synthesis of New N-OMe Fluoro-Indole Melatoninergics

Volume:3   Issue: 6
Pp: 561-571
A. Tsotinis, J. Gourgourinis, A. Eleutheriades, K. Davidson and D. Sugden
DOI: 10.2174/157340607782360335

New Steroidal Anti-Inflammatory Antedrugs: 21-Thioalkylether Derivatives of Methyl 16-Prednisolone Carboxylates

Volume:3   Issue: 6
Pp: 572-575
M. Omar F. Khan, Kwan K. Park, Sharye N. Glynn and Henry J. Lee
DOI: 10.2174/157340607782360317

Computational Approach to Drug Design for Oxazolidinones as Antibacterial Agents

Volume:3   Issue: 6
Pp: 576-582
Yun Li, Dong-Qing Wei, Wei-Na Gao, Hui Gao, Bing-Ni Liu, Chang-Jiang Huang, Wei-Ren Xu, Deng-Ke Liu, Hai-Feng Chen and Kuo-Chen Chou
DOI: 10.2174/157340607782360362

Synthesis of Opioidmimetics, 3-[H-Dmt-NH(CH2)m]-6-[H-Dmt-NH(CH2)n]-2(1H)-pyrazinones, and Studies on Structure-Activity Relationships

Volume:3   Issue: 6
Pp: 583-598
Kimitaka Shiotani, Anna Miyazaki, Tingyou Li, Yuko Tsuda, Toshio Yokoi, Akihiro Ambo, Yusuke Sasaki, Sharon D. Bryant, Yunden Jinsmaa, Lawrence H. Lazarus and Yoshio Okada
DOI: 10.2174/157340607782360272

Peptide-Based Soft Materials as Potential Drug Delivery Vehicles

Volume:3   Issue: 6
Pp: 605-611
Sandeep Verma, K. B. Joshi and Surajit Ghosh
DOI: 10.2174/157340607782360371