Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume: 3 Issue: 1, January

Author Index Volume 2 open Access plus

Volume:3   Issue: 1
Pp: vi-vi

DOI: 10.2174/15734064107030100vi
Published on: 01 March, 2012

Subject Index Volume 2 open Access plus

Volume:3   Issue: 1
Pp: xi-xi

DOI: 10.2174/15734064107030100xi
Published on: 01 March, 2012

Inhibitor Design for SARS Coronavirus Main Protease Based on “Distorted Key Theory” open Access plus

Volume:3   Issue: 1
Pp: 1-6
Qi-Shi Du, Hao Sun and Kuo-Chen Chou
DOI: 10.2174/157340607779317616
Published on: 01 March, 2012

Effect of a M1 Allosteric Modulator on Scopolamine-Induced Amnesia open Access plus

Volume:3   Issue: 1
Pp: 7-11
J. Espinosa-Raya, M. Espinoza-Fonseca, O. Picazo and J. Trujillo-Ferrara
DOI: 10.2174/157340607779317526
Published on: 01 March, 2012

Biophysical Characterization of the Interaction of Endotoxins with Hemoglobins open Access plus

Volume:3   Issue: 1
Pp: 13-20
Jorg Howe, Malte Hammer, Christian Alexander, Manfred Rossle, Karin Fournier, Jean-Pierre Mach, Thierry Waelli, Reginald M. Gorczynski, Artur J. Ulmer, Ulrich Zahringer and Klaus Brandenburg
DOI: 10.2174/157340607779317625
Published on: 01 March, 2012

Spectrophotometric Quantification of Bilirubin in Hemorrhagic Spinal Fluid using an Innovative Algorithm open Access plus

Volume:3   Issue: 1
Pp: 21-27
Prashant R. Bhadri, Vasant A. Salgaonkar, Gail J. Pyne-Geithman, James J. Caffery, Rakesh Shukla, Fred R. Beyette and Joseph F. Clark
DOI: 10.2174/157340607779317562
Published on: 01 March, 2012

N-acetylcysteine Exerts Protective Effects and Prevents Lung Redox Imbalance and Peroxynitrite Generation in Endotoxemic Rats open Access plus

Volume:3   Issue: 1
Pp: 29-34
Luis F. Carbonell, Julian Diaz, Isabel Hernandez, Santiago Cuevas, Fernando Valero, Tomas Quesada, Francisco Fenoy and Miguel G. Salom
DOI: 10.2174/157340607779317580
Published on: 01 March, 2012

Synthetic Derivatives of Osthole for the Prevention of Hepatitis open Access plus

Volume:3   Issue: 1
Pp: 35-44
Toshihiro Okamoto, Tadashi Kobayashi and Shinic hi Yoshida
DOI: 10.2174/157340607779317607
Published on: 01 March, 2012

Derivatives of Cephalothin that Inhibit Ampicillin Resistant Escherichia Coli open Access plus

Volume:3   Issue: 1
Pp: 45-49
Ronald Bartzatt, Suat L G. Cirillo and Jeffrey D. Cirillo
DOI: 10.2174/157340607779317571
Published on: 01 March, 2012

Isolation, Structural Determination, and Evaluation of the Biological Activity of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol [20(S)-25-OCH3-PPD], a Novel Natural Product from Panax notoginseng open Access plus

Volume:3   Issue: 1
Pp: 51-60
Y. Zhao, W. Wang, L. Han, E R. Rayburn, D. L. Hil, H. Wang and R. Zhang
DOI: 10.2174/157340607779317508
Published on: 01 March, 2012

Analogy of Cardiac and Renal Complications in Essential Hypertension and Aged SHR or L-NAME/SHR open Access plus

Volume:3   Issue: 1
Pp: 61-65
Xiaoyan Zhou and Edward D. Frohlich
DOI: 10.2174/157340607779317634
Published on: 01 March, 2012

Design and Synthesis of 2-Methylthio-3-substituted-5,6-dimethylthieno [2,3-d] pyrimidin-4(3H)-ones as Analgesic, Anti-Inflammatory and Antibacterial Agents open Access plus

Volume:3   Issue: 1
Pp: 67-73
V. Alagarsamy, V. Raja Solomon, R. Meenac, K. V. Ramaseshu, K. Thirumurugan and S. Murugesan
DOI: 10.2174/157340607779317599
Published on: 01 March, 2012

3D-QSAR CoMFA Study on Oxindole Derivatives as Cyclin Dependent Kinase 1 (CDK1) and Cyclin Dependent Kinase 2 (CDK2) Inhibitors open Access plus

Volume:3   Issue: 1
Pp: 75-84
Sanjeev Kumar Singh, Nigus Dessalew and Prasad V. Bharatam
DOI: 10.2174/157340607779317517
Published on: 01 March, 2012

Synthesis of Pyrophosphate-Containing Compounds that Stimulate VγVδ2 T Cells: Application to Cancer Immunotherapy open Access plus

Volume:3   Issue: 1
Pp: 85-99
Y. Tanaka, H. Kobayashi, T. Terasaki, H. Toma, A. Aruga, T. Uchiyama, K. Mizutani, B. Mikami, C. T. Morita and N. Minato
DOI: 10.2174/157340607779317544
Published on: 01 March, 2012

Metabolism of Moexipril to Moexiprilat: Determination of In Vitro Metabolism Using HPLC-ES-MS open Access plus

Volume:3   Issue: 1
Pp: 101-106
H. Kalasz, G. Petroianu, K. Tekes, I. Klebovich, K. Ludanyi and Zs. Gulyas
DOI: 10.2174/157340607779317490
Published on: 01 March, 2012

Processing of Small Molecule Databases for Automated Docking open Access plus

Volume:3   Issue: 1
Pp: 107-113
Maxwell D. Cummings, Alan C. Maxwell and Renee L. DesJarlais
DOI: 10.2174/157340607779317481
Published on: 01 March, 2012