Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Volume: 2 Issue: 4, July

New Substrate Analogue Inhibitors of Factor Xa Containing 4-Amidinobenzylamide as P1 Residue: Part 1

Volume:2   Issue: 4
Pp: 349-361
Torsten Steinmetzer, Jorg Sturzebecher, Oliver Schuster, Uta Sturzebecher, Andrea Schweinitz and Anne Sturzebecher
DOI: 10.2174/157340606777724040
Published on: 01 March, 2012

Classical QSAR Study on Chromene Derivatives as Lanosterol 14α -Demethylase Inhibitor: A Non Azole Antifungal Target

Volume:2   Issue: 4
Pp: 363-367
S. G. Kaskhedikar, M. A. Babu, M. Lakshmi and P. Vasanthanathan
DOI: 10.2174/157340606777724004
Published on: 01 March, 2012

Medicinal Chemistry of Probimane and MST-16: Comparison of Anticancer Effects Between Bisdioxopiperazines

Volume:2   Issue: 4
Pp: 369-375
Bin Xu, Jian Ding, Hong Zhu, Cheng-Hui Xu, Min Huang and Da-Yong Lu
DOI: 10.2174/157340606777724095
Published on: 01 March, 2012

Cytoprotective Effects of 5 Benzophenones and a Xanthone from Hypericum annulatum in Models of Epirubicin-Induced Cytotoxicity: SARAnalysis and Mechanistic Investigations

Volume:2   Issue: 4
Pp: 377-384
Margarita Karaivanova, Ulrich Girreser, Tzvetomira Tzanova, Gerassim M. Kitanov, Dimitrina Zh.Zheleva-Dimitrova, Paraskev T. Nedialkov and Georgi Momekov
DOI: 10.2174/157340606777724103
Published on: 01 March, 2012

Physico-Chemical Profiling of Antidepressive Sertraline: Solubility,Ionisation, Lipophilicity

Volume:2   Issue: 4
Pp: 385-389
Karoly Tihanyi, Bela Noszal, Krisztina Takacs-Novak and Katalin Deak
DOI: 10.2174/157340606777723997
Published on: 01 March, 2012

Cyclosporin-A in the Treatment of Nephrotic Syndrome: The Importance of Monitoring C0 (Trough) and C2 (Two Hours After its Administration) Blood Levels

Volume:2   Issue: 4
Pp: 391-393
John G. Vlachojannis, Irene Savidaki, Pantelitsa Kalliakmani, Sotiris Tsakas and D. S. Goumenos
DOI: 10.2174/157340606777724068
Published on: 01 March, 2012

A Novel Family of Minimal PMRI Cyclic Peptides as Versatile Scaffolds for Generating New Molecular Topology

Volume:2   Issue: 4
Pp: 395-400
Cristina Tiozzo, Federico Squassabia, Alessandra Tolomelli, Luca Gentilucci and Giuliana Cardillo
DOI: 10.2174/157340606777724077
Published on: 01 March, 2012

Molecular Interactions Between Human Cytochrome P450 1A2 and Flavone Derivatives

Volume:2   Issue: 4
Pp: 401-406
Maria Joao Ramos, Francesco Iori, Maria Cristina Menziani, Andre Melo and Rute da Fonseca
DOI: 10.2174/157340606777723988
Published on: 01 March, 2012

Folic Acid as a Fenton-modulator: Possible Physiological Implication

Volume:2   Issue: 4
Pp: 407-413
Subrata Chattopadhyay, Birija S. Patro, Soumyakanti Adhikari and Tulsi Mukherjee
DOI: 10.2174/157340606777724059
Published on: 01 March, 2012

The Structure - Antituberculosis Activity Relationships Study in a Series of 5-(4-Aminophenyl)-4-Substituted-2,4-Dihydro-3h-1,2,4-Triazole-3-Thione Derivatives. A Combined Electronic-Topological and Neural Networks Approach

Volume:2   Issue: 4
Pp: 415-422
Fatma Kandemirli, Nathali Shvets, Seda Unsalan, Ilkay Kucukguzel, Sevim Rollas, Vasyl Kovalishyn and Anatholy Dimoglo
DOI: 10.2174/157340606777724013
Published on: 01 March, 2012

Does the Septic Shock Interfere Experimental Acute Pancreatitis in Rats?

Volume:2   Issue: 4
Pp: 423-429
S. Hac, M. Dobosz, J. J. Kaczor, S. Dobrowolski, J. Krajewski, R. Rzepko, Z. Gruca and Z. Sledzinski
DOI: 10.2174/157340606777724031
Published on: 01 March, 2012

Retinoids in Clinical Use

Volume:2   Issue: 4
Pp: 431-438
Vincent C. O. Njar, Lalji Gediya, Puranik Purushottamachar, Panka Chopra, Aashvini Belosay and Jyoti B. Patel
DOI: 10.2174/157340606777724022
Published on: 01 March, 2012