Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume:15   Issue: 6
Pp: 571-571
Mariusz Skwarczynski
DOI: 10.2174/157340641506190619105911



The Latest Researches of Enzyme Inhibition and Multi-Target Drug Predictors in Medicinal Chemistry promotion: free to download

Volume:15   Issue: 6
Pp: 572-573
Guo-Ping Zhou
DOI: 10.2174/157340641506190826145925



Advances in Structural Biology of ACE and Development of Domain Selective ACE-inhibitors

Volume:15   Issue: 6
Pp: 574-587
Mája Polakovičová* and Josef Jampílek
DOI: 10.2174/1573406415666190514081132




Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity

Volume:15   Issue: 6
Pp: 602-623
Ahmed M. Abdelaziz, Sarah Diab, Saiful Islam, Sunita K.C. Basnet, Benjamin Noll, Peng Li, Laychiluh B. Mekonnen, Jingfeng Lu, Hugo Albrecht, Robert W. Milne, Cobus Gerber, Mingfeng Yu * and Shudong Wang*
DOI: 10.2174/1573406415666181219111511




New Quinazoline-Sulfonylurea Conjugates: Design, Synthesis and Hypoglycemic Activity

Volume:15   Issue: 6
Pp: 634-647
Sahar M. Abou-Seri, AlShaimaa M. Taha, Mona A. Mohamed* and Nour M. Abdelkader
DOI: 10.2174/1573406415666181208104543




Efficacy of Novel Schiff base Derivatives as Antifungal Compounds in Combination with Approved Drugs Against Candida Albicans

Volume:15   Issue: 6
Pp: 648-658
Manzoor Ahmad Malik, Shabir Ahmad Lone, Parveez Gull, Ovas Ahmad Dar, Mohmmad Younus Wani, Aijaz Ahmad* and Athar Adil Hashmi*
DOI: 10.2174/1573406415666181203115957




Design, Synthesis, Antimicrobial and Anti-biofilm Evaluation, and Molecular Docking of Newly Substituted Fluoroquinazolinones

Volume:15   Issue: 6
Pp: 659-675
Mohamed F. Zayed, Sabrin R.M. Ibrahim*, EL-Sayed E. Habib, Memy H. Hassan, Sahar Ahmed and Heba S. Rateb
DOI: 10.2174/1573406414666181109092944




Discovery and Optimization of a Series of Sulfonamide Inverse Agonists for the Retinoic Acid Receptor-Related Orphan Receptor-α

Volume:15   Issue: 6
Pp: 676-684
Christelle Doebelin, Yuanjun He, Sean Campbell, Philippe Nuhant, Naresh Kumar, Marcel Koenig, Ruben Garcia-Ordonez, Mi Ra Chang, William R. Roush, Li Lin, Susan Kahn, Michael D. Cameron, Patrick R. Griffin, Laura A. Solt* and Theodore M. Kamenecka*
DOI: 10.2174/1573406415666190222124745




Design, Synthesis and Antiplasmodial Evaluation of Sulfoximine-triazole Hybrids as Potential Antimalarial Prototypes

Volume:15   Issue: 6
Pp: 685-692
Tommy F. Mabasa, Babatunde Awe, Dustin Laming and Henok H. Kinfe*
DOI: 10.2174/1573406415666190206232308




Synthesis, Plasmodium falciparum Inhibitory Activity, Cytotoxicity and Solubility of N2 ,N4 -Disubstituted Quinazoline-2,4-diamines.

Volume:15   Issue: 6
Pp: 693-704
Nattakarn Pobsuk, Praphasri Suphakun, Supa Hannongbua, Chanin Nantasenamat, Kiattawee Choowongkomon and M. Paul Gleeson*
DOI: 10.2174/1573406415666181219100307




Polyethylene Glycol Acts as a Mechanistic Stabilizer of L-asparaginase: A Computational Probing

Volume:15   Issue: 6
Pp: 705-714
Rajashekar Sindhu, Hanumanthappa Pradeep and Haravey K. Manonmani*
DOI: 10.2174/1573406415666190206232816