Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume:15   Issue: 5
Pp: 439-440
Wolf-Rainer Abraham
DOI: 10.2174/157340641505190506125012



Medicinal Chemistry Driven by the Development of System Biology & Cheminformatics free to download

Volume:15   Issue: 5
Pp: 441-442
Guo-Ping Zhou and Jianyong Li
DOI: 10.2174/157340641505190506125340



The Multiple Applications and Possible Mechanisms of the Hyperbaric Oxygenation Therapy

Volume:15   Issue: 5
Pp: 459-471
Wan Chen, Xingmei Liang, Zhihuan Nong, Yaoxuan Li, Xiaorong Pan, Chunxia Chen* and Luying Huang*
DOI: 10.2174/1573406415666181219101328




pLoc_bal-mEuk: Predict Subcellular Localization of Eukaryotic Proteins by General PseAAC and Quasi-balancing Training Dataset promotion: free to download

Volume:15   Issue: 5
Pp: 472-485
Kuo-Chen Chou*, Xiang Cheng and Xuan Xiao
DOI: 10.2174/1573406415666181218102517




The Inhibition of Polysialyltranseferase ST8SiaIV Through Heparin Binding to Polysialyltransferase Domain (PSTD) promotion: free to download

Volume:15   Issue: 5
Pp: 486-495
Li-Xin Peng, Xue-Hui Liu, Bo Lu, Si-Ming Liao, Feng Zhou, Ji-Min Huang, Dong Chen, Frederic A. Troy II, Guo-Ping Zhou* and Ri-Bo Huang*
DOI: 10.2174/1573406415666181218101623




pLoc_bal-mVirus: Predict Subcellular Localization of Multi-Label Virus Proteins by Chou's General PseAAC and IHTS Treatment to Balance Training Dataset promotion: free to download

Volume:15   Issue: 5
Pp: 496-509
Xuan Xiao*, Xiang Cheng, Genqiang Chen, Qi Mao and Kuo-Chen Chou
DOI: 10.2174/1573406415666181217114710




Inhibition of α-amylase Activity by Zn2+: Insights from Spectroscopy and Molecular Dynamics Simulations

Volume:15   Issue: 5
Pp: 510-520
Si-Ming Liao, Nai-Kun Shen, Ge Liang, Bo Lu, Zhi-Long Lu, Li-Xin Peng, Feng Zhou, Li-Qin Du, Yu-Tuo Wei, Guo-Ping Zhou* and Ri-Bo Huang*
DOI: 10.2174/1573406415666181217114101




Synthesis and Biological Evaluation of Polyfluoroalkylated Antipyrines and their Isomeric O-Methylpyrazoles

Volume:15   Issue: 5
Pp: 521-536
Natalya Agafonova, Evgeny Shchegolkov*, Yanina Burgart, Victor Saloutin, Alexandra Trefilova, Galina Triandafilova, Sergey Solodnikov, Vera Maslova, Olga Krasnykh, Sophia Borisevich and Sergey Khursan
DOI: 10.2174/1573406414666181106145435




Synthesis and Biological Studies of New Multifunctional Curcumin Platforms for Anticancer Drug Delivery

Volume:15   Issue: 5
Pp: 537-549
Andrii Bazylevich, Helena Tuchinsky, Eti Zigman-Hoffman, Ran Weissman, Ofer Shpilberg, Oshrat Hershkovitz-Rokah, Leonid Patsenker and Gary Gellerman*
DOI: 10.2174/1573406415666181203112220




Anticancer Activity and Topoisomerase II Inhibition of Naphthalimides with ω-Hydroxylalkylamine Side-Chains of Different Lengths

Volume:15   Issue: 5
Pp: 550-560
Mateusz D. Tomczyk, Anna Byczek-Wyrostek, Klaudia Strama, Martyna Wawszków, Przemysław Kasprzycki and Krzysztof Z. Walczak*
DOI: 10.2174/1573406414666180912105851




Design, Synthesis and In Vitro Evaluation of Novel Anti-HIV 3-Pyrazol-3- yl-Pyridin-2-One Analogs

Volume:15   Issue: 5
Pp: 561-570
Sanjay Kumar, Shiv Gupta, Shraddha Gaikwad, Leila F. Abadi, Late K. K. Bhutani, Smita Kulkarni* and Inder P. Singh*
DOI: 10.2174/1573406414666181106125539