Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume:14   Issue: 6
Pp: 549-549
Gerard Marx
DOI: 10.2174/157340641406180712092944



Antibacterial Assessment of Heteroaryl, Vinyl, Benzyl, and Alkyl Tetrazole Compounds

Volume:14   Issue: 6
Pp: 550-555
Joshua Dudley, Liana Feinn, Heather DeFrancesco, Erica Lindsay, Adiel Coca* and Elizabeth Lewis Roberts
DOI: 10.2174/1573406413666171120162420




Anti-Trypanosoma cruzi Activity in vitro of Phases and Isolated Compounds from Excoecaria lucida Leaves

Volume:14   Issue: 6
Pp: 556-562
Cristiane F. da Silva*, Ania O. Pacheco, Rayane N. Alves, Josean F. Tavares, Marcelo S. da Silva and Julio C.E. Arranz
DOI: 10.2174/1573406414666180112112154




Design, Synthesis and Biological Evaluation of 7-arylbenzo[c]acridine-5,6- diones as Potential Anti-Leishmanial and anti-trypanosomal Agents

Volume:14   Issue: 6
Pp: 563-572
Shivani Mahajan, Shabana I. Khan, Babu L. Tekwani, Ikhlas A. Khan and Inder P. Singh*
DOI: 10.2174/1573406414666180226163222




Evaluation of Trypanocidal and Antioxidant Activities of a Selected Series of 3-amidocoumarins

Volume:14   Issue: 6
Pp: 573-584
Mauricio Moncada-Basualto, Michel Lapier, Juan Diego Maya, Betty Matsuhiro, Claudio Olea-Azar*, Giovanna L. Delogu, Eugenio Uriarte, Lourdes Santana and Maria Joao Matos*
DOI: 10.2174/1573406414666180419113437




Synthesis and Antibacterial Activity Against MRSA of Pleuromutilin Derivatives Possessing a Mercaptoethylamine Linker

Volume:14   Issue: 6
Pp: 585-594
Zhao-Sheng Zhang, Yun-Zhen Huang, Jian Luo, Bing-Feng Wang, Zhen Jin, Ya-Hong Liu and You-Zhi Tang*
DOI: 10.2174/1573406414666180416131737




Synthesis of a Novel Class of 1,3-oxathiolane Nucleoside Derivatives of T- 705 and Evaluation of Their Anti-influenza A Virus and Anti-HIV Activity

Volume:14   Issue: 6
Pp: 595-603
Mingming Han, Xu Zhao, Xuedong Wu, Wei Huang, Xingzhou Li* and Fang Yu*
DOI: 10.2174/1573406414666180112102225




Construction of an M1GS Ribozyme for Targeted and Rapid mRNA Cleavage; Application on the Ets-2 Oncogene

Volume:14   Issue: 6
Pp: 604-616
Chrisavgi Toumpeki, Dimitrios Anastasakis, Ioannis Panagoulias, Vassiliki Stamatopoulou, Tassos Georgakopoulos, Sofia Kallia-Raftopoulos, Athanasia Mouzaki* and Denis Drainas*
DOI: 10.2174/1573406414666180112115201




Synthesis of Oleanolic Acid Analogues and Their Cytotoxic Effects on 3T3 Cell Line

Volume:14   Issue: 6
Pp: 617-625
Salih Tuncay, Halil Senol, Eray Metin Guler, Nuket Ocal *, Hasan Secen, Abdurrahim Kocyigit and Gulacti Topcu*
DOI: 10.2174/1573406414666180222094544




Molecular Interaction and Computational Analytical Studies of Pinocembrin for its Antiangiogenic Potential Targeting VEGFR-2: A Persuader of Metastasis

Volume:14   Issue: 6
Pp: 626-640
Neha Sharma, Mala Sharma, Eram Shakeel, Qazi M.S. Jamal, Mohammad A. Kamal, Usman Sayeed, Mohammad K.A. Khan, Mohammad H. Siddiqui, Jamal M. Arif and Salman Akhtar*
DOI: 10.2174/1573406414666180416125121




Anti-diabetic Phenolic Compounds of Black Carrot (Daucus carota Subspecies sativus var. atrorubens Alef.) Inhibit Enzymes of Glucose Metabolism: An in silico and in vitro Validation

Volume:14   Issue: 6
Pp: 641-649
Suhas G. Karkute, Tanmay K. Koley*, Bijen K. Yengkhom, Ajay Tripathi, Shivani Srivastava, Arti Maurya and Bijendra Singh
DOI: 10.2174/1573406414666180301092819