Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Volume:14   Issue: 5
Pp: 427-427
Diego Alves
DOI: 10.2174/157340641405180706121129

Emerging Roles of Purinergic Signaling in Diabetes

Volume:14   Issue: 5
Pp: 428-438
Carmen Fotino*, Diego Dal Ben and Elena Adinolfi*
DOI: 10.2174/1573406414666180226165204

Facile Synthesis, Crystal Structure, DFT Calculation and Biological Activities of 4-(2-fluorophenyl)-3-(3-methoxybenzyl)-1H-1,2,4-triazol-5 (4H)-one (5)

Volume:14   Issue: 5
Pp: 451-459
Muhammad Saleem, Muhammad Rafiq, Yeon Ki Jeong, Dae Won Cho, Chong-Hyeak Kim, Sung-Yum Seo, Chang-Shik Choi, Seong-Karp Hong and Ki Hwan Lee*
DOI: 10.2174/1573406414666180112122856

Activity of Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside, its Hydrochloride, and N,N-dialkyl Derivatives Against Non-albicans Candida Isolates

Volume:14   Issue: 5
Pp: 460-467
Malgorzata A. Dawgul*, Daria Grzywacz, Beata Liberek, Wojciech Kamysz and Henryk Myszka
DOI: 10.2174/1573406414666180226164747

Synthesis and Structure-Activity Relationship; Exploration of some Potent Anti-Cancer Phenyl Amidrazone Derivatives

Volume:14   Issue: 5
Pp: 468-477
Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Sanaa K. Bardaweel and Mutasem O. Taha*
DOI: 10.2174/1573406414666171204143157

Scaffold Hopping Strategy for the Design, Synthesis and Biological Activity Evaluation of Novel Hexacyclic Scutellarein Derivatives with a 1,3-Oxazine Ring Fused at A-ring

Volume:14   Issue: 5
Pp: 478-484
Yue Zhong, Yu-Ting Lu, Ying Sun, Nian-Guang Li, Ting Gu, Wen-Yu Wu, Shao-Peng Yu and Zhi-Hao Shi*
DOI: 10.2174/1573406413666170906130251

Design and Synthesis of 3,4-diarylpyrrole Analogues as Potent Topoisomerase Inhibitors

Volume:14   Issue: 5
Pp: 485-494
Wang Chen*, Zili Feng, Xu He, Qiang Zhao and Qi Liang
DOI: 10.2174/1573406414666180226164049

Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

Volume:14   Issue: 5
Pp: 495-507
Tugba Gungor, Gulden Yetis, Ferah C. Onder, Esra Tokay, Tugba T. Tok, Ayhan Celik, Mehmet Ay* and Feray Kockar
DOI: 10.2174/1573406413666171129224424

Inhibition of Adipogenesis by Thiourea Derivatives

Volume:14   Issue: 5
Pp: 508-515
Hina Siddiqui*, Sarah Shafi, Farah Mukhtar, Asma Ejaz, Atta-ur-Rahman and M. Iqbal Choudhary*
DOI: 10.2174/1573406413666171120161208

Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes

Volume:14   Issue: 5
Pp: 516-523
Humera Jahan*, Muhammad I. Choudhary, Amber Atta, Khalid M. Khan and Atta- ur-Rahman
DOI: 10.2174/1573406413666171020120528

Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones

Volume:14   Issue: 5
Pp: 524-535
Humaira Zafar, Sarosh Iqbal, Sumaira Javaid, Khalid M. Khan* and Muhammad I. Choudhary*
DOI: 10.2174/1573406413666171129224919

New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies

Volume:14   Issue: 5
Pp: 536-548
Sahar Yousuf, Khalid M. Khan*, Uzma Salar, Almas Jabeen, Shakil Ahmed, Munira T. Muhammad, Aisha Faheem and Shahnaz Perveen
DOI: 10.2174/1573406414666180112122001