Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

Personal Subscription
Become EABM
Become Reviewer



Meet Our Editorial Board Member free to download

Volume:14   Issue: 5
Pp: 427-427
Diego Alves
DOI: 10.2174/157340641405180706121129



Emerging Roles of Purinergic Signaling in Diabetes

Volume:14   Issue: 5
Pp: 428-438
Carmen Fotino*, Diego Dal Ben and Elena Adinolfi*
DOI: 10.2174/1573406414666180226165204




Facile Synthesis, Crystal Structure, DFT Calculation and Biological Activities of 4-(2-fluorophenyl)-3-(3-methoxybenzyl)-1H-1,2,4-triazol-5 (4H)-one (5)

Volume:14   Issue: 5
Pp: 451-459
Muhammad Saleem, Muhammad Rafiq, Yeon Ki Jeong, Dae Won Cho, Chong-Hyeak Kim, Sung-Yum Seo, Chang-Shik Choi, Seong-Karp Hong and Ki Hwan Lee*
DOI: 10.2174/1573406414666180112122856




Activity of Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside, its Hydrochloride, and N,N-dialkyl Derivatives Against Non-albicans Candida Isolates

Volume:14   Issue: 5
Pp: 460-467
Malgorzata A. Dawgul*, Daria Grzywacz, Beata Liberek, Wojciech Kamysz and Henryk Myszka
DOI: 10.2174/1573406414666180226164747




Synthesis and Structure-Activity Relationship; Exploration of some Potent Anti-Cancer Phenyl Amidrazone Derivatives

Volume:14   Issue: 5
Pp: 468-477
Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Sanaa K. Bardaweel and Mutasem O. Taha*
DOI: 10.2174/1573406414666171204143157




Scaffold Hopping Strategy for the Design, Synthesis and Biological Activity Evaluation of Novel Hexacyclic Scutellarein Derivatives with a 1,3-Oxazine Ring Fused at A-ring

Volume:14   Issue: 5
Pp: 478-484
Yue Zhong, Yu-Ting Lu, Ying Sun, Nian-Guang Li, Ting Gu, Wen-Yu Wu, Shao-Peng Yu and Zhi-Hao Shi*
DOI: 10.2174/1573406413666170906130251




Design and Synthesis of 3,4-diarylpyrrole Analogues as Potent Topoisomerase Inhibitors

Volume:14   Issue: 5
Pp: 485-494
Wang Chen*, Zili Feng, Xu He, Qiang Zhao and Qi Liang
DOI: 10.2174/1573406414666180226164049




Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

Volume:14   Issue: 5
Pp: 495-507
Tugba Gungor, Gulden Yetis, Ferah C. Onder, Esra Tokay, Tugba T. Tok, Ayhan Celik, Mehmet Ay* and Feray Kockar
DOI: 10.2174/1573406413666171129224424




Inhibition of Adipogenesis by Thiourea Derivatives

Volume:14   Issue: 5
Pp: 508-515
Hina Siddiqui*, Sarah Shafi, Farah Mukhtar, Asma Ejaz, Atta-ur-Rahman and M. Iqbal Choudhary*
DOI: 10.2174/1573406413666171120161208




Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes

Volume:14   Issue: 5
Pp: 516-523
Humera Jahan*, Muhammad I. Choudhary, Amber Atta, Khalid M. Khan and Atta- ur-Rahman
DOI: 10.2174/1573406413666171020120528




Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones

Volume:14   Issue: 5
Pp: 524-535
Humaira Zafar, Sarosh Iqbal, Sumaira Javaid, Khalid M. Khan* and Muhammad I. Choudhary*
DOI: 10.2174/1573406413666171129224919




New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies

Volume:14   Issue: 5
Pp: 536-548
Sahar Yousuf, Khalid M. Khan*, Uzma Salar, Almas Jabeen, Shakil Ahmed, Munira T. Muhammad, Aisha Faheem and Shahnaz Perveen
DOI: 10.2174/1573406414666180112122001