Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume:12   Issue: 7
Pp: 601-601
Inder Pal Singh
DOI: 10.2174/157340641207160927215128



Synthesis, Cytotoxic Activity on Leukemia Cell Lines and Quantitative Structure-Activity Relationships (QSAR) Studies of Morita-Baylis-Hillman Adducts

Volume:12   Issue: 7
Pp: 602-612
Claudio G. Lima–Junior, Gláucia V. Faheina–Martins, Caio C. B. Bomfim, Bruna B. Dantas, Everton P. Silva, Demetrius A. M. de Araújo, Edilson B. A. Filho and Mário L. A. A. Vasconcellos
DOI: 10.2174/1573406412666160506150924




Integrated In Silico-In Vitro Discovery of Lung Cancer-related Tumor Pyruvate Kinase M2 (PKM2) Inhibitors

Volume:12   Issue: 7
Pp: 613-620
Xiangyun Ye, Yinjia Sun, Yunhua Xu, Zhiwei Chen and Shun Lu
DOI: 10.2174/1573406412666160307151535




Design, Synthesis, and Cytotoxicity of Novel 2,4,6-Trisubstituted 1,3,5- triazines Bearing Aryl Hydrazone Moiety as Potent Antitumor Agent

Volume:12   Issue: 7
Pp: 621-630
Limei Wang, Sijia Zhao, Guanglong Bao, Yu Zhang, Shuancheng Xi, Guolin Zhou, Xin Zhai and Ping Gong
DOI: 10.2174/1573406412666160106154551




Synthesis and Biological Evaluation of Novel 1,3,4-thiadiazole Derivatives Incorporating Benzisoselenazolone Scaffold as Potential Antitumor Agents

Volume:12   Issue: 7
Pp: 631-639
Xiaoyun Fu, Sha Li, Fen Jing, Xuefeng Wang, Baolin Li, Jijun Zhao, Yuming Liu and Baoquan Chen
DOI: 10.2174/1573406412666160201120806




Synthesis and Antifungal Activity of Some 4,6-Dimethylisoxazolo[3,4- b]pyridin-3(1H)-one Derivatives

Volume:12   Issue: 7
Pp: 640-646
Jaroslaw Saczewski, Joanna Fedorowicz, Anna Kedzia, Marta Ziolkowska-Klinkosz and Aleksandra Jalinska
DOI: 10.2174/1573406412666160517122925




Antiplasmodial Limonoids from Trichilia rubescens (Meliaceae)

Volume:12   Issue: 7
Pp: 655-661
Tsamo T. Armelle, Nangmo K. Pamela, Mkounga Pierre, Ingrid B. Müller, Kirk Marat, Gabriele Sass and Nkengfack A. Ephrem
DOI: 10.2174/1573406412666160106154357




Three Arachidonoylamide Derivatives Inhibit Pro-Inflammatory Genes Expression by Modulating NF-κB and AP1 Activities

Volume:12   Issue: 7
Pp: 662-673
Alex Gregorelli, Anna Sgarbossa, Shahbaz Khan, Annunziata Soriente, Margherita De Rosa, Carmela Saturnino and Marta Menegazzi
DOI: 10.2174/1573406412666160502154936




Synthesis, in vivo Anticoagulant Evaluation and Molecular Docking Studies of Bicoumarins Obtained from Furocoumarin Peucedanin

Volume:12   Issue: 7
Pp: 674-683
Alla V. Lipeeva, Mikhail V. Khvostov, Dmitry S. Baev, Makhmut M. Shakirov, Tatijana G. Tolstikova and Elvira E. Shults
DOI: 10.2174/1573406412666160129105115




Biologically Active New N, N', N''-Tri-Substituted Ferrocenyl Phenylguanidines and their Characterization

Volume:12   Issue: 7
Pp: 684-698
Rukhsana Gul, Ataf A. Altaf, Amin Badshah, Afzal Shah, Zia ur Rehman, Rabia Naz, Muhammad N. Tahir and Asif Junaid
DOI: 10.2174/1573406412666160129104817