Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume:12   Issue: 5
Pp: 403-403
Paul Zarogoulidis
DOI: 10.2174/157340641205160623175738

Chemosensitization of Prostate Carcinoma Cells with a Receptor-directed Smac Conjugate

Volume:12   Issue: 5
Pp: 412-418
Alexander Sturzu, Sumbla Sheikh, Hartmut Echner, Martin Deeg, Thomas Nägele, Christopher Weidenmaier, Christian Schwentner, Marius Horger, Ulrike Ernemann and Stefan Heckl
DOI: 10.2174/1573406412666151112125622

Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells

Volume:12   Issue: 5
Pp: 419-425
Duc Duy Vo, Isabelle Rouaud, Francoise Le Devehat, Fabien Gautier, Sophie Barillé-Nion, Philippe Juin, Nicolas Levoin, Joël Boustie and René Grée
DOI: 10.2174/1573406412666160129104603

Synthesis, Structural Characterization of a Novel Ferrocene Derivative and Preliminarily Anticancer Activity

Volume:12   Issue: 5
Pp: 426-431
Jianping Yong, Xiaoyuan Wu, Jianzhen Liao, Canzhong Lu and Xiaolong Liu
DOI: 10.2174/1573406412666151112125345

Cytotoxic Effects of Salvinorin A, A Major Constituent of Salvia divinorum

Volume:12   Issue: 5
Pp: 432-440
Ana Martinho, Sara M. Silva and Eugenia Gallardo
DOI: 10.2174/1573406411666151005105617

Synthesis and Anti-thyroid Cancer Effect of Iodo-chrysin Derivatives

Volume:12   Issue: 5
Pp: 441-447
Yun Wei, Qutong Zheng, Guotao Tang, Chen Song, Guan Wang, Yinxiang Zhang, Yan Xiao, Xianliang Zeng, Zongbao Wang, Jichang Xiao and Xing Zheng
DOI: 10.2174/1573406411666150921111220

In-Vitro Anticancer Evaluation and Docking Study of Novel Benzo[g] Quinazoline-sulfonamide Derivatives

Volume:12   Issue: 5
Pp: 448-456
Mostafa M. Ghorab, Mansour S. Alsaid, Mohamed S. Al-Dosary and Marwa G. El-Gazzar
DOI: 10.2174/1573406412666160201120921

Chemical Composition and Inhibitory Effects of Hypericum brasiliense and H. connatum on Prolyl Oligopeptidase and Acetylcholinesterase Activities

Volume:12   Issue: 5
Pp: 457-463
Maura Z. dos Santos, Ionara I. Dalcol, Luciana Adolpho, Meritxell Teixidó, Teresa Tarragó, Ademir Morel and Ernest Giralt
DOI: 10.2174/1573406411666151026121845

DNA Hybridization on Chitosan-Functionalized Silicon Substrate

Volume:12   Issue: 5
Pp: 464-471
Amina Omar, El-Sayed M. El-Sayed, Mona S. Talaat and Medhat Ibrahim
DOI: 10.2174/1573406412666151112124836

Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach

Volume:12   Issue: 5
Pp: 472-477
Engi A. Hassaan, Sara C. Sigler, Tamer M. Ibrahim, Kevin J. Lee, Lauren K. Cichon, Bernard D. Gary, Joshua C. Canzoneri, Gary A. Piazza and Ashraf H.Abadi
DOI: 10.2174/1573406412666151204002836

Antimicrobial and Anti-biofilm Activity of Thiourea Derivatives Bearing 3-amino-1H-1,2,4-triazole Scaffold

Volume:12   Issue: 5
Pp: 478-488
Joanna Stefanska, Karolina Stepien, Anna Bielenica, Daniel Szulczyk, Barbara Miroslaw, Anna E Koziol, Giuseppina Sanna, Filippo Iuliano, Silvia Madeddu, Michal Jozwiak and Marta Struga
DOI: 10.2174/1573406412666151204003146

Design, Synthesis and Antiproliferative Activity of Novel Benzothiazole Derivatives Conjugated with Semicarbazone Scaffold

Volume:12   Issue: 5
Pp: 489-498
Guanglong Bao, Baoquan Du, Yuxiu Ma, Meng Zhao, Ping Gong and Xin Zhai
DOI: 10.2174/1573406412666160107113343