Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume:11   Issue: 4
Pp: 315-315
Andreas Hilgeroth
DOI: 10.2174/157340641104150429125656



Meet Our Editorial Board Member free to download

Volume:11   Issue: 4
Pp: 316-316
Kuo-Chen Chou
DOI: 10.2174/157340641104150429125757

Design of SGLT2 Inhibitors for the Treatment of Type 2 Diabetes: A History Driven by Biology to Chemistry

Volume:11   Issue: 4
Pp: 317-328
Wenqing Cai, Linlin Jiang, Yafei Xie, Yuqiang Liu, Wei Liu and Guilong Zhao
DOI: 10.2174/1573406411666150105105529


Discovery of 9,10-Dihydroacridines as Novel Class of ABCB1 Inhibitors

Volume:11   Issue: 4
Pp: 329-335
Andreas Hilgeroth, Marc Hemmer, Sebastian Neuber, Josef Molnar and Hermann Lage
DOI: 10.2174/1573406410666141111100720


Synthesis and Biological Potential Assessment of 2-Substituted Quinazolin-4(3H)-ones as Inhibitors of Phosphodiesterase-I and Carbonic Anhydrase-II

Volume:11   Issue: 4
Pp: 336-341
Syed Muhammad Saad, Muhammad Saleem, Shahnaz Perveen, Muhammad Tanveer Alam, Khalid Mohammed Khan and Muhammad Iqbal Choudhary
DOI: 10.2174/1573406410666141203123926


Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors

Volume:11   Issue: 4
Pp: 342-353
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Stefania Baraldi, Filippo Prencipe, Delia Preti, Giulia Saponaro, Romeo Romagnoli, Stefania Gessi, Stefania Merighi, Angela Stefanelli, Debora Fazzi, Pier Andrea Borea, Rodolfo Couto Maia, Nelilma C. Romeiro, Carlos A. M. Fraga and Eliezer J. Barreiro
DOI: 10.2174/1573406411666141210141317


New Benzimidazole-Derived Isothioureas as Potential Antileukemic Agents - Studies In Vitro

Volume:11   Issue: 4
Pp: 364-372
Miroslawa Koronkiewicz, Anna Romiszewska, Zdzislaw Chilmonczyk and Zygmunt Kazimierczuk
DOI: 10.2174/1573406410666141203124329


Antiproliferative Effect of Novel Aminoacridine-based Compounds

Volume:11   Issue: 4
Pp: 373-382
Anna Munder, Yoni Moskovitz, Boris Redko, Ariel Rachel Levy, Sharon Ruthstein, Gary Gellerman and Arie Gruzman
DOI: 10.2174/1573406411666141217110946


Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes open access plus

Volume:11   Issue: 4
Pp: 383-390
Huizhen Cai, Fukang Liu, Pingguo Zuo, Guiling Huang, Zhixiu Song, Tingting Wang, Huixia Lu, Fei Guo, Chao Han and Guiju Sun
DOI: 10.2174/1573406410666141110153858


Long Term Stability Evaluation of Prostacyclin Released from Biomedical Device through Turbiscan Lab Expert open access plus

Volume:11   Issue: 4
Pp: 391-399
Christian Celia, Marcello Locatelli, Felisa Cilurzo, Donato Cosco, Emanuela Gentile, Daniela Scalise, Maria Carafa, Cinzia Anna Ventura, Mathias Fleury, Christelle Tisserand, Renato. C Barbacane, Massimo Fresta, Luisa Di Marzio and Donatella Paolino
DOI: 10.2174/1573406410666141110153502


Identification of Imidazoquinoline Derivatives as Potent Antiglioma Agents

Volume:11   Issue: 4
Pp: 400-406
Shivaputra A. Patil, Susan R. Pfeffer, William L. Seibel, Lawrence M. Pfeffer and Duane D. Miller
DOI: 10.2174/1573406410666140914162701


Design, Synthesis and Antimicrobial Evaluation of Methyl Pyridyl-2,4- Dioxobutanoates and Some New Derived Ring Systems

Volume:11   Issue: 4
Pp: 407-414
Perihan A.S. Elzahhar, Raafat Soliman, Soad A.M. El-Hawash, Hanan M.A. Ragab, Amal M. Youssef and Abeer E. Abdel Wahab
DOI: 10.2174/1573406411666141205102544