Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki

Nobel Laureate on Editorial Board

Prof. Ferid Murad

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Volume: 1 Issue: 1, January


Volume:1   Issue: 1
Pp: 1-1
DOI: 10.2174/1573406053402514
Published on: 01 March, 2012

Synthesis of A/B-Ring Partial Analogs of Bruceantin as Potential Antimalarial Agents

Volume:1   Issue: 1
Pp: 3-11
Z. Guo, S. Vangapandu, A. Nimrod, L. A. Walker and R. D. Sindelar
DOI: 10.2174/1573406053402488
Published on: 01 March, 2012

A Novel Achiral seco-Amino-Cyclopropylindoline (CI) Analog of CC-1065 and the Duocarmycins: Design, Synthesis and Biological Studies

Volume:1   Issue: 1
Pp: 13-19
James L. Toth, John D. Trzupek, Lloyd V. Flores, Konstantinos Kiakos, John A. Hartley, William T. Pennington and Moses Lee
DOI: 10.2174/1573406053402523
Published on: 01 March, 2012

Novel Experimental Design for Steady-state Processes: A Systematic Bayesian Approach for Enzymes, Drug Transport, Receptor Binding, Continuous Culture and Cell Transport Kinetics

Volume:1   Issue: 1
Pp: 21-29
M. James C. Crabbe, Emma F. Murphy and Steven G. Gilmour
DOI: 10.2174/1573406053402550
Published on: 01 March, 2012

Influence of Trishomocubanes on Sigma Receptor Binding of N-(1-Benzylpiperidin- 4-yl)-4-[123I]iodobenzamide In Vivo in the Rat Brain

Volume:1   Issue: 1
Pp: 31-38
Xiang Liu, Filomena Mattner, Andrew Katsifis, MacDonald Christie and Michael Kassiou
DOI: 10.2174/1573406053402541
Published on: 01 March, 2012

A New Nucleotide-composition Based Fingerprint of SARS-CoV with Visualization Analysis

Volume:1   Issue: 1
Pp: 39-47
Meng Wang, Jin-Song Yao, Zhen-De Huang, Zhi-Jie Xu, Guo-Ping Liu, Hai-Yong Zhao, Xue-Yong Wang, Jie Yang, Yi-Sheng Zhu and Kuo-Chen Chou
DOI: 10.2174/1573406053402505
Published on: 01 March, 2012

Apoptosis Signaling Pathways in Lung Diseases

Volume:1   Issue: 1
Pp: 49-56
K. Kuwano, M. Yoshimi, T. Maeyama, N. Hamada, M. Yamada and Y. Nakanishi
DOI: 10.2174/1573406053402497
Published on: 01 March, 2012

Full Length and Delta Lactoferrin Display Differential Cell Localization Dynamics, but do not Act as Tumor Markers or Significantly Affect the Expression of Other Genes

Volume:1   Issue: 1
Pp: 57-64
Gary S. Goldberg, Takehiko Kunimoto, David B. Alexander, Kayoko Suenaga, Fumiyoshi Ishidate, Kazuaki Miyamoto, Toshikazu Ushijima, Christina T. Teng, Jun Yokota, Tsutomu Ohta and Hiroyuki Tsuda
DOI: 10.2174/1573406053402532
Published on: 01 March, 2012

Cytotoxicity of an Ebulin l-Anti-Human CD105 Immunotoxin on Mouse Fibroblasts (L929) and Rat Myoblasts (L6E9) Cells Expressing Human CD105

Volume:1   Issue: 1
Pp: 65-71
Jorge Benitez, J. Miguel Ferreras, Raquel Munoz, Yolanda Arias, Rosario Iglesias, Manuel Cordoba-Diaz, Rosario del Villar and Tomas Girbes
DOI: 10.2174/1573406053402479
Published on: 01 March, 2012

Protease Inhibitors in the Clinic

Volume:1   Issue: 1
Pp: 71-104
Giovanni Abbenante and David P. Fairlie
DOI: 10.2174/1573406053402569
Published on: 01 March, 2012