Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Open Access Articles

Synthesis, Antimicrobial Evaluation and Docking Study of Novel 3,5-Disubstituted-2-Isoxazoline and 1,3,5-Trisubstituted-2-Pyrazoline Derivatives open Access plus

Volume: 17   Issue: 5
Pp: 462-473
Ahmed H. Ismail, Ahmed M. Abdula*, Ivan H.R. Tomi, Ali H.R. Al-Daraji and Younis Baqi*
DOI:10.2174/1573406415666191107121757

Prospects for Discovering the Secondary Metabolites of Cordyceps Sensu Lato by the Integrated Strategy open Access plus

Volume: 17   Issue: 2
Pp: 97-120
Shabana Bibi, Yuan-Bing Wang, De-Xiang Tang, Mohammad Amjad Kamal and Hong Yu*
DOI:10.2174/1573406416666191227120425

Synthesis, Cytotoxicity, Anti-migration and Anti-Invasion Activity of Diphyllin Heterocyclic Derivatives open Access plus

Volume: 17  
Pp: 1-8
Weidong Shen, Haijiao Chen, Miaomiao Wu, Ting Zhang, Li Zhu and Yu Zhao*
DOI:10.2174/1573406417666201221160220

Synthesis, Cytotoxicity, ADMET and Molecular Docking Studies of Some Quinoline-Pyrimidine Hybrid Compounds: 3-(2-Amino-6-arylpyrimidin-4- yl)-4-hydroxy-1-methylquinolin-2(1H)-ones open Access plus

Volume: 17  
Pp: 1-15
Duong Ngoc Toan*, Nguyen Dinh Thanh*, Mai Xuan Truong and Dinh Thuy Van
DOI:10.2174/1573406417666201230092615

Chalcones as Scavengers of HOCl and Inhibitors of Oxidative Burst: Structure-Activity Relationship Studies open Access plus

Volume: 17  
Pp: 1-9
Thaise Martins, Vera L.M. Silva, Artur M.S. Silva, José L.F.C. Lima, Eduarda Fernandes* and Daniela Ribeiro*
DOI:10.2174/1573406417666201230093207

Synthesis, Molecular Docking, BSA, and In-Vitro Reactivation Study of Imidazopyridine Oximes Against Paraoxon Inhibited Acetylcholinesterase open Access plus

Volume: 17  
Pp: 1-15
Ashima Thakur, Jayant Patwa, Abha Sharma* and Swaran Jeet Singh Flora
DOI:10.2174/1573406417666210208223240

Pyrazoles and Fused Pyrimidines: Synthesis, Structure Elucidation, Antitubercular Activity and Molecular Docking Study open Access plus

Volume: 17  
Pp: 1-18
Amerah M. Al-Soliemy, Rehab Sabour and Thoraya A. Farghaly*
DOI:10.2174/1573406417666210324131951

Anti-Mycobacterial Peroxides: A New Class of Agents for Development Against Tuberculosis open Access plus

Volume: 16   Issue: 3
Pp: 392-402
Christiaan W. van der Westhuyzen, Richard K. Haynes, Jenny-Lee Panayides, Ian Wiid and Christopher J. Parkinson*
DOI:10.2174/1573406415666190430143535

Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity open Access plus

Volume: 15   Issue: 6
Pp: 602-623
Ahmed M. Abdelaziz, Sarah Diab, Saiful Islam, Sunita K.C. Basnet, Benjamin Noll, Peng Li, Laychiluh B. Mekonnen, Jingfeng Lu, Hugo Albrecht, Robert W. Milne, Cobus Gerber, Mingfeng Yu * and Shudong Wang*
DOI:10.2174/1573406415666181219111511

The Evaluation of Metal Co-ordinating Bis-Thiosemicarbazones as Potential Anti-malarial Agents open Access plus

Volume: 15   Issue: 1
Pp: 51-58
Fady N. Akladios, Scott D. Andrew, Samantha J. Boog, Carmen de Kock, Richard K. Haynes and Christopher J. Parkinson*
DOI:10.2174/1573406414666180525132204