Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

Personal Subscription
Become EABM
Become Reviewer
Call for Editor

Most Accessed Articles

Evaluation of Novel Substituted Furopyridines as Inhibitors of Protein Kinases Related to Tau Pathology in Alzheimer´s Disease

Volume: 17   Issue: 8
Pp: 844-855
N. Schade, P. Koch, F. Ansideri, V. Krystof, M. Holzer and A. Hilgeroth*
DOI: 10.2174/1573406417666210601144510

Synthesis of Novel 1,2,3-Triazole Derivatives of Isocoumarins and 3,4- Dihydroisocoumarin with Potential Antiplasmodial Activity In Vitro

Volume: 17   Issue: 8
Pp: 820-833
Lucas da Silva Santos, Matheus Fillipe Langanke de Carvalho, Ana Claudia de Souza Pinto, Amanda Luisa da Fonseca, Julio César Dias Lopes, Fernando de Pilla Varotti, Rossimiriam Pereira de Freitas and Rosemeire Brondi Alves*
DOI: 10.2174/1573406416666200602161047

Identification and Expression Analysis of CD73 Inhibitors in Cervical Cancer

Volume: 17   Issue: 8
Pp: 866-874
Jamshed Iqbal*, Ayesha Basharat, Sehrish Bano, Syed Mobasher Ali Abid, Julie Pelletier and Jean Sévigny
DOI: 10.2174/1573406416666200925141703

Synthesis and Evaluation of Cytotoxicity of Novel Coumarin Peptide Alcohol Derivatives

Volume: 17   Issue: 8
Pp: 926-936
Digamber S. Pawar, Vasant V. Chabukswar*, Savita R. Tapase, Kisan M. Kodam, Anurudhha Chabukswar, Pravin B. Adhav, Balasaheb B. Diwate, Sunita Salunke Gawali, Sabrina Dallavalle and Swati C. Jagdale
DOI: 10.2174/1573406416666200817155056

Indane-1,3-diones: As Potential and Selective α-glucosidase Inhibitors, their Synthesis, in vitro and in silico Studies

Volume: 17   Issue: 8
Pp: 887-902
Asma Mukhtar, Shazia Shah, Kanwal, Shehryar Hameed, Khalid. Mohammed Khan*, Shahid Ullah Khan, Sumera Zaib, Jamshed Iqbal* and Shahnaz Perveen
DOI: 10.2174/1573406416666200826102051

Chalcones: As Potent α-amylase Enzyme Inhibitors; Synthesis, In Vitro, and In Silico Studies

Volume: 17   Issue: 8
Pp: 903-912
Mahboob Ali, Momin Khan*, Khair Zaman, Abdul Wadood, Maryam Iqbal, Aftab Alam, Sana Shah, Ashfaq Ur Rehman, Muhammad Yousaf, Rafaila Rafique and Khalid Mohammed Khan
DOI: 10.2174/1573406416666200611103039

Antidiabetic and Antioxidative Properties of Novel Zn(II)-cinnamic Acid Complex

Volume: 17   Issue: 8
Pp: 913-925
Chika I. Chukwuma*, Samson S. Mashele and Shasank S. Swain
DOI: 10.2174/1573406416666200929143257

Spiro Heterocyclic Compounds as Potential Anti-Alzheimer Agents (Part 2): Their Metal Chelation Capacity, POM Analyses and DFT Studies

Volume: 17   Issue: 8
Pp: 834-843
Taibi Ben Hadda*, Fatma Sezer Senol Deniz, Ilkay Erdogan Orhan, Hsaine Zgou, Abdur Rauf, Yahia Nasser Mabkhot*, Brahim Bennani, Dalia R. Emam, Nabila Abdelshafy Kheder, Abdulrhman Asayari, Abdullatif Bin Muhsinah and Aneela Maalik*
DOI: 10.2174/1573406416666200610185654

Pyrazole Derivatives of Medically Relevant Phenolic Acids: Insight into Antioxidative and Anti-LOX Activity

Volume: 17   Issue: 8
Pp: 807-819
Vesna Milovanović, Zorica D. Petrović*, Slađana Novaković, Goran A. Bogdanović, Dušica Simijonović, Milan Mladenović, Jovica Branković and Vladimir P. Petrović
DOI: 10.2174/1573406416666200602152643

Novel Conjugated Quinazolinone-Based Hydroxamic Acids: Design, Synthesis and Biological Evaluation

Volume: 17   Issue: 7
Pp: 732-749
Tran Khac Vu*, Nguyen Thi Thanh, Nguyen Van Minh, Nguyen Huong Linh, Nguyen Thi Phương Thao, Trương Thuc Bao Nguyen, Doan Thi Hien, Luu Van Chinh, Ta Hong Duc, Lai Duc Anh and Pham-The Hai
DOI: 10.2174/1573406416666200420081540

Synthesis and Anticancer Activity of Thiadiazole Containing Thiourea, Benzothiazole and Imidazo[2,1-b][1,3,4]thiadiazole Scaffolds

Volume: 17   Issue: 7
Pp: 750-765
Stephen Paul Avvaru, Malleshappa N. Noolvi*, Uttam A More, Sudipta Chakraborty, Ashutosh Dash, Tejraj M. Aminabhavi, Kumar P. Narayan and Vishnu Sutariya
DOI: 10.2174/1573406416666200519085626

Synthesis, Molecular Docking Studies and Antibacterial Activities of Novel Monocationic Indole-benzimidazole Derivatives

Volume: 17   Issue: 7
Pp: 699-706
Zeynep Ates-Alagoz*, Mehmet Murat Kisla, Hakan Goker and Sulhiye Yildiz
DOI: 10.2174/1573406416666200420080459

Curcumin-based Antioxidant and Glycohydrolase Inhibitor Compounds: Synthesis and In Vitro Appraisal of the Dual Activity Against Diabetes

Volume: 17   Issue: 7
Pp: 677-698
Sajjad Esmaeili, Nazanin Ghobadi, Donya Nazari, Alireza Pourhossein, Hassan Rasouli, Hadi Adibi* and Reza Khodarahmi*
DOI: 10.2174/1573406416666200506083718

Synthesis, Antimicrobial Evaluation and Docking Study of Novel 3,5-Disubstituted-2-Isoxazoline and 1,3,5-Trisubstituted-2-Pyrazoline Derivatives open access plus

Volume: 17   Issue: 5
Pp: 462-473
Ahmed H. Ismail, Ahmed M. Abdula*, Ivan H.R. Tomi, Ali H.R. Al-Daraji and Younis Baqi*
DOI: 10.2174/1573406415666191107121757

Synthesis of thiazolyl-N-phenylmorpholine Derivatives and their Biological Activities

Volume: 17   Issue: 7
Pp: 790-805
Amerah M. Al-Soliemy, Thoraya A. Farghaly*, Eman M. H. Abbas, Mohamed R. Shaaban*, Mohie E. M. Zayed and Tarek B. A. El-Naggar
DOI: 10.2174/1573406416666200517103435

Structure-Based Virtual Screening of New Benzoic Acid Derivatives as Trypanosoma cruzi Trans-sialidase Inhibitors

Volume: 17   Issue: 7
Pp: 724-731
Lenci Karina Vázquez-Jiménez, Alma Delia Paz-González, Alfredo Juárez-Saldivar, María Laura Uhrig, Rosalía Agusti, Alicia Reyes-Arellano, Benjamín Nogueda-Torres and Gildardo Rivera*
DOI: 10.2174/1573406416666200506084611

Synthesis and Cytotoxic Activity of Novel Mono- and Bis-Indole Derivatives: Analogues of Marine Alkaloid Nortopsentin

Volume: 17   Issue: 7
Pp: 779-789
Mona Monir Kamel, Mohamed Kamal Abdel-hameid, Hala Bakr El-Nassan* and Eman Adel El-Khouly
DOI: 10.2174/1573406416666200509235305