Letters in Organic Chemistry

One-pot Pseudo-Domino Three-Component Knoevenagel Condensation Reaction in Water Enabled by Micellar Catalyst: Mechanism and Reactivity

Volume: 17   Issue: 11
Pp: 823-831
Dini Ahanthem, Devi Prasan Ojha, Francis A.S. Chipem and Warjeet S. Laitonjam*
DOI: 10.2174/1570178616666190701102542

Squaramide-Catalyzed Enantioselective Michael Addition of Pyrazol-3- ones to ortho-Quinone Methides

Volume: 17   Issue: 11
Pp: 837-844
Laura Carceller-Ferrer, Gonzalo Blay, José R. Pedro* and Carlos Vila
DOI: 10.2174/1876402911666190806105543

Synthesis of Highly Functionalized Quinazoline-2,4(1H,3H)-diones from Isocyanides, Aniline and Isocyanate via Cu-Catalyzed Intermolecular C-H Activation Reactions

Volume: 17   Issue: 11
Pp: 832-836
Manijeh Nematpour, Hossein Fasihi Dastjerdi, Mehdi Jahani and Sayyed Abbas Tabatabai*
DOI: 10.2174/1570178616666190905142545

4-Anilidopiperidine Derivatives for in vivo Imaging of μ-Opioid Receptors

Volume: 17   Issue: 11
Pp: 845-856
János Marton*, Attila Sipos, Sándor Berényi, Brita Glaenzel and Gjermund Henriksen*
DOI: 10.2174/1570178616666190905144136

Chiral Mn(III) Salen Complex Immobilized on CuFe2O4@SiO2-NH2 NPs: A Cheap and Efficient Catalyst for N-arylation of Aryl Halides and Phenylboronic Acid Under Mild Conditions

Volume: 17   Issue: 11
Pp: 857-863
Mohammad Ali Nasseri *, Seyyedeh Ameneh Alavi, Milad Kazemnejadi and Ali Allahresani
DOI: 10.2174/1570178616666190919110639

An Effective Assembling of Novel Derivatives Containing Both Benzo[d]thiazole and Benzo[d]oxazole Rings

Volume: 17   Issue: 11
Pp: 815-822
Nguyen Thi Ngoc Mai, Duong Quoc Hoan*, Vu Thi Anh Tuyet, Tran Thi Thu Trang, Duong Khanh Linh and Trinh Thi Huan
DOI: 10.2174/1570178617666200207104912

Improvements in the Acylation of 3-Methylindole Using Amberlyst-15

Volume: 17   Issue: 11
Pp: 890-896
Darío A. Vargas, Leticia J. Mendez and Alicia S. Cánepa*
DOI: 10.2174/1570178617666200207110109

2,5-Dihydroxyterephthalic Acid Accelerated Cu(NO3)2 .3H2O-Catalyzed Homocoupling Reaction of Arylboronic Acids

Volume: 17   Issue: 11
Pp: 877-883
Fengtian Wu, Chenlong Nan, Jianwei Xie and Mingyang Ma*
DOI: 10.2174/1570178617666200210110041

Computational Study on the Kinetics and Mechanisms of Unimolecular Reactions of (Z)-(Z)-N-(λ5-phosphanylidene) Formohydrazonic Formic Anhydride: Intramolecular aza-Wittig Reaction in Competition with Mumm Rearrangement

Volume: 17   Issue: 11
Pp: 884-889
Somayeh Mirdoraghi, Hamed Douroudgari, Farideh Piri and Morteza Vahedpour*
DOI: 10.2174/1570178617666200224103813

Design, Synthesis and Anticancer Evaluation of Acetamides Comprising 1,2,3-triazole, 1,3,4-thiadiazole and Isothiazolo[4,3-b]pyridine Rings

Volume: 17   Issue: 11
Pp: 864-871
Shaik Shahinshavali, Nuthalapati Poojith, Venkat Rao Guttikonda, Reddymasu Sreenivasulu and Mandava Venkata Basaveswara Rao*
DOI: 10.2174/1570178617666200225102939

Exploring the Neighbouring Group Participatory Mechanism in Glycosylation Reaction

Volume: 17   Issue: 11
Pp: 872-876
Kamlesh Sharma*
DOI: 10.2174/1570178617666200225104704

Synthesis of New C2-Symmetric Chiral Benzimidazole Derivatives Having Norbornene/Dibenzobarrelene Skeletons

Volume: 17   Issue: 10
Pp: 800-804
Irfan Capan and Suleyman Servi*
DOI: 10.2174/1570178616666190731105327

The Study on Chlorination by Sulfuryl Chloride of Benzene/Pyridine Carboxamides and Carbonitriles

Volume: 17   Issue: 10
Pp: 787-793
Weiqing Yang, Yongjing Cao, Hongrui Cheng, Qingrong Sun and Menglin Ma*
DOI: 10.2174/1570178617666191203101254

A Computational Study of the Conformational Behavior of 2,5-Dimethyl- 1,4-dithiane-2,5-diol and Analogous S and Se: DFT and NBO Study

Volume: 17   Issue: 10
Pp: 748-758
Elmira Danaie, Shiva Masoudi* and Nasrin Masnabadi
DOI: 10.2174/1570178617666200129144750

Synthesis of (E)-1,2-Bis[4-[di(1H-pyrrol-2-yl)methyl]phenyl]ethene as a New Bis(dipyrromethane) Building Block

Volume: 17   Issue: 10
Pp: 794-799
Faride Ranjbari, Salar Hemmati* and Mohammad Reza Rashidi
DOI: 10.2174/1570178617666200207102604

In-Situ Synthesis of Active Pharmaceutical Ingredients Which Content Pyrazole Skeleton

Volume: 17   Issue: 10
Pp: 743-747
Pathan Sultan Ismail, Repale Anil Vithal and Girdhar Pal Singh*
DOI: 10.2174/1570178617666200207110526

Synthesis of 5-amino-1-aryl-3-methyl-1H-pyrazole-4-carbonitriles, Antifungal Activity and In Silico Analysis

Volume: 17   Issue: 10
Pp: 778-786
Luciana Terra, Daiane de Jesus Viegas, Alice Maria Rolim Bernardino, Jéssica Venância Faria, Percilene Fazolin Vegi, Rômulo Gabriel De Miranda de Paula Pinto, Maurício Silva dos Santos, Helena Carla Castro and Paula Alvarez Abreu*
DOI: 10.2174/1570178617666200210105246

Computational Study on the Mechanism of Cycloaddition Reactions of Bissulfonyl-1,3-butadiene with Some Alkenes

Volume: 17   Issue: 10
Pp: 735-742
Sepideh Masoumifar, Mina Haghdadi* and Hassan Ghasemnejad Bosra
DOI: 10.2174/1570178617666200210112307

Preparation and Characterization of Soybean Oil-based Flame Retardant Rigid Polyurethane Foams Containing Phosphaphenanthrene Groups

Volume: 17   Issue: 10
Pp: 759-770
Qirui Gong, Niangui Wang*, Kaibo Zhang, Shizhao Huang and Yuhan Wang
DOI: 10.2174/1570178617666200224104336

Arylhydrazono/Aryldiazenyl Pyrazoles: Green One-Pot Solvent-Free Synthesis and Anticancer Evaluation

Volume: 17   Issue: 10
Pp: 771-777
Abdulrhman Alsayari, Abdullatif Bin Muhsinah, Yahya I. Asiri, Jaber Abdullah Alshehri, Yahia N. Mabkhot, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Mater H. Mahnashi and Mohd. Zaheen Hassan*
DOI: 10.2174/1570178617666200320104923

Efficient Synthesis of 2-[(3,4-Dichlorophenyl)methyl]-1H-benzimidazole Derivatives, and their α-Glucosidase Inhibitory and Antioxidant Activities

Volume: 17   Issue: 10
Pp: 805-813
Emre Menteşe, Fatih Yılmaz* and Nimet Baltaş
DOI: 10.2174/1570178617666200330130024

PEG1000 as a Low Melting and Ecofriendly Solvent for Air Oxidative and Catalyst Free 2,4-Disubstitute Quinazoline Synthesis

Volume: 17   Issue: 9
Pp: 709-716
Ebrahim Saeedian Moghadam, Shahrzad Ghafary and Mohsen Amini*
DOI: 10.2174/1570178616666190417122005

Asymmetric Reactions in Water Catalyzed by L-Proline Tethered on Thermoresponsive Ionic Copolymers open access plus

Volume: 17   Issue: 9
Pp: 717-725
Noriyuki Suzuki*, Daisuke Mizuno, Armando M. Guidote Jr., Shun Koyama, Yoshiro Masuyama and Masahiro Rikukawa
DOI: 10.2174/1570178616666190819141307

Cytotoxic Prenyl and Geranyl Coumarins from the Stem Bark of Casimiroa edulis

Volume: 17   Issue: 9
Pp: 680-687
Khun Nay Win Tun, Nanik Siti Aminah*, Alfinda Novi Kristanti, Rico Ramadhan and Yoshiaki Takaya
DOI: 10.2174/1570178616666191019121437

A Novel Copper-Catalyzed Synthesis of N-Monosubstituted 2-Alkynimidamides from 1-Alkynes and Trichloroacetamidines

Volume: 17   Issue: 9
Pp: 704-708
Hossein Fasihi Dastjerdi, Manijeh Nematpour, Elham Rezaee, Mehdi Jahani and Sayyed Abbas Tabatabai*
DOI: 10.2174/1570178616666191023142821

MoO3 Nanoparticles as an Efficient Catalyst for the Synthesis of Pyrazoles in Aqueous-alcoholic Medium at Room Temperature

Volume: 17   Issue: 9
Pp: 694-703
Sonatai Patil*, Ananda Mane and Savita Dhongade-Desai
DOI: 10.2174/1570178617666191127103433

Thiazolidine-2, 4-Diones as Non-Hepatotoxic Tri-action Drug Candidates: Design, Synthesis, Characterization, Biological Evaluation and Docking Studies

Volume: 17   Issue: 9
Pp: 659-679
Karuna S. Shukla, Shailendra Pandey and Pooja A. Chawla*
DOI: 10.2174/1570178617666191220142852

Synthesis, Photophysics and Theoretical Calculation of (E)-2-(benzo[d] thiazol-2-yl)-3-(3-methoxyphenyl)acrylonitrile

Volume: 17   Issue: 9
Pp: 688-693
Pei-Chieh Wu and Chih-Hsien Chen*
DOI: 10.2174/1570178617666200207103147

A Rationale for the Ortho Effect in Electrophilic Aromatic Substitutions

Volume: 17   Issue: 9
Pp: 655-658
Timothy Eckert*, Grace Harmeyer, Steven Legate and Steven Mathe
DOI: 10.2174/1570178617666200207103755

Trifunctionalized Allenes. Part IV. Cyclization Reactions of 4-Phosphorylated 5-Hydroxyhexa-2,3-dienoates

Volume: 17   Issue: 9
Pp: 726-733
Ismail E. Ismailov, Ivaylo K. Ivanov and Valerij Ch. Christov*
DOI: 10.2174/1570178617666200225104238

Active γ –Alumina -Supported Ru Nanoparticles for CO2 Hydrogenation Reaction

Volume: 17   Issue: 8
Pp: 603-612
Prashant Gautam and Vivek Srivastava*
DOI: 10.2174/1570178617666191107112429

Metal-Free Synthesis of Pyrimidinone Derivatives via Biginelli Reaction Using Aqueous NaICl2

Volume: 17   Issue: 8
Pp: 613-617
Navnath T. Hatvate, Shrikant M. Ghodse, Krishna N. Mundlod and Vikas N. Telvekar*
DOI: 10.2174/1570178617666191126095808

Application of Amine-based Ru Compounds in the Olefin Metathesis of Methyl Eugenol: A Comparison with Grubbs Catalysts

Volume: 17   Issue: 8
Pp: 596-602
Denise A. Sousa, Paulo S. Meneses, Patrik D.S. Gois, Eliada A. Silva, Valdemiro P.C. Junior, Benedito S. Lima-Neto and José L. Silva Sá*
DOI: 10.2174/1570178617666191127102552

Synthesis of C3-Quaternary 2H-Pyrrolines by [3+2] Cycloaddition of Isocyanoacetates and 1,1-Disubstituted Alkenes

Volume: 17   Issue: 8
Pp: 586-589
Yi Cheng, Runmei Zhang, Tianhao Lu, Yong Shen, Min Wang and Chunsong Xie*
DOI: 10.2174/1570178617666191218104959

Chiral Catalysts Utilized in the Nucleophilic Addition of Dialkyl-zinc Reagents to Carbonyl Compounds

Volume: 17   Issue: 8
Pp: 571-585
Adnan Cetin*
DOI: 10.2174/1570178617666191220145038

Synthesis, Antibacterial and Antioxidant Activities of Some New Nsubstituted Azachalcone, Schiff base and Pyrazole Derivatives

Volume: 17   Issue: 8
Pp: 631-638
Nedime Çalışkan, Asu Usta*, Fatih Şaban Beriş, Nimet Baltaş and Efsun Çelik
DOI: 10.2174/1570178617666200108111211

Trihaloisocyanuric Acids: Useful Reagents for Conversion of Benzaldehydes into Benzylidene Dihalides under Appel Conditions

Volume: 17   Issue: 8
Pp: 590-595
Haryadylla da C. Sindra, Carlos Vinícius P. dos Santos and Marcio C.S. de Mattos*
DOI: 10.2174/1570178617666200121110618

Synthesis, Crystal Structure, Luminescence, and Nonlinear Optical Properties of 2-[(E)-[[4-[2-(4-Methoxyphenyl)ethynyl]phenyl] imino]methyl]-4- [(E)-phenyldiazenyl]phenol

Volume: 17   Issue: 8
Pp: 618-623
Sagar Subhash Mohite, Aditya Babasaheb Patil-Deshmukh and Sanjay Shamrao Chavan*
DOI: 10.2174/1570178617666200207104157

Synthesis of TFA-protected α-Amino Acid Chloride via a Vilsmeier Reagent for Friedel–Crafts acylation

Volume: 17   Issue: 8
Pp: 645-653
Zetryana Puteri Tachrim, Kazuhiro Oida, Fumina Ohashi, Natsumi Kurokawa, Lei Wang, Takeyuki Suzuki and Makoto Hashimoto *
DOI: 10.2174/1570178617666200207111127

A Simple Synthesis of the Anticancer Drug Altretamine

Volume: 17   Issue: 8
Pp: 628-630
Vu Binh Duong, Pham Van Hien, Tran Thai Ngoc, Phan Dinh Chau and Tran Khac Vu*
DOI: 10.2174/1570178617666200210111041

Regioselective IED Diels-Alder Reaction of Bis-(4,6-dichloro-[1,3,5]triazin- 2-yl)-diazene with Furan and Its Molecular Mechanism

Volume: 17   Issue: 8
Pp: 639-644
Andrew Karkhut, Sviatoslav Polovkovych, Roman Lesyk* and Volodymyr Novikov
DOI: 10.2174/1570178617666200210111928

Facile One-Pot Synthesis and Crystal Structure of 2:1 Adducts of Myrcene (or Ocimene) with Benzoquinones

Volume: 17   Issue: 8
Pp: 624-627
Sujata V. Bhat*, Rohan S. Pawar and P. Rajakannu
DOI: 10.2174/1570178617666200227110001

Multi-component Preparation of Pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidines Using Solvent-free and HSBM Techniques

Volume: 17   Issue: 7
Pp: 512-516
Seyyed Jalal Roudbaraki, Morteza Ziyaadini and Majid Ghashang*
DOI: 10.2174/1570178616666190319155522

Efficient and Regioselective Ring-opening of Epoxides with Carboxylic Acid Catalyzed by Graphite Oxide

Volume: 17   Issue: 7
Pp: 532-538
Maryam Mirza-Aghayan*, Mahdieh Molaee Tavana, Elaheh Golam Alipour Niazi and Rabah Boukherroub
DOI: 10.2174/1570178616666190401194252

Synthesis and Characterization of GO-Chit-Ni Nanocomposite as a Recoverable Nanocatalyst for Reducing Nitroarenes in Water

Volume: 17   Issue: 7
Pp: 523-531
Mosayeb Sarvestani and Roya Azadi*
DOI: 10.2174/1570178616666190806125217

Zeolite Catalyzed Friedel-Crafts Reactions: A Review

Volume: 17   Issue: 7
Pp: 491-506
Yogeesha N. Nayak, Swarnagowri Nayak, Y.F. Nadaf, Nitinkumar S. Shetty and Santosh L. Gaonkar*
DOI: 10.2174/1570178616666190807101012

One-Pot Green Synthesis of Some Novel N-Substituted 5-Amino-1,3,4- Thiadiazole Derivatives

Volume: 17   Issue: 7
Pp: 517-522
Azizollah Habibi *, Sahar Khosravi , Seyyed M. Shahcheragh and Mohd B. Abdul Rahman
DOI: 10.2174/1570178616666190926105533

Dual Catalytic Activity of Amberlyst-15 in the Large-scale and Sustainable Synthesis of Dioctyl Sodium Sulfosuccinate (DOSS)

Volume: 17   Issue: 7
Pp: 555-559
Mojtaba Tarin*, Seyed M.M. Moghadam, Samie Salehi and Davod S. Fateh*
DOI: 10.2174/1570178616666191009105703

Green and Efficient Synthesis of Fluorescent Bis(pyrazolyl)methanes in Choline Chloride/Urea Deep Eutectic Solvent

Volume: 17   Issue: 7
Pp: 548-554
Adeleh Moshtaghi Zonouz*, Masoumeh Beiranvand, Rahim Mohammad-Rezaei and Soheila Naderi
DOI: 10.2174/1570178617666191111121813

Synthesis, Characterization and Antimicrobial Activity Evaluation of the Polybenzimidazole Derivatives with Different Dicarboxylic Acid Moieties

Volume: 17   Issue: 7
Pp: 539-547
Bilge Eren*, Fadime Özdemir Koçak and Gülcan Erdoğan
DOI: 10.2174/1570178617666191114105457

An Efficient Ultrasonic-Assisted Synthesis of Enol Carbamates via Oxidative Coupling of Formamides with 1,3-Dicarbonyl Compounds

Volume: 17   Issue: 7
Pp: 507-511
Jafar Akbari* and Alireza Akbari Meyestani
DOI: 10.2174/1570178617666191126095420

Synthesis, Toxicity Profile and Pharmacological Evaluation of Some New N,N-Diphenyl Amine Derivatives with Special Reference to Analgesic and Anti-inflammatory Activity

Volume: 17   Issue: 7
Pp: 560-570
Arvind Kumar* and Arun K. Mishra
DOI: 10.2174/1570178617666191220150024

Preparation, Characterization, and Application of Ru-Silica-Ionic Liquid System for CO2 Hydrogenation Reaction

Volume: 17   Issue: 6
Pp: 443-454
Prashant Gautam, Praveenkumar Ramprakash Upadhyay and Vivek Srivastava*
DOI: 10.2174/1570178616666190429150333

Facile Access to 2-Substituted Benzoxazoles Using Sawdust Supported N-Heterocyclic Carbene-Ni Complex via C-H Activation

Volume: 17   Issue: 6
Pp: 479-489
Dolly Kale, Gajanan Rashinkar, Audumbar Patil, Arjun Kumbhar and Rajashri Salunkhe*
DOI: 10.2174/1570178616666190705153927

The Difference in Sensing Properties Towards Anions between Two Pyridinium Amide-Based Receptors with a Subtle Change of H-Bond Position

Volume: 17   Issue: 6
Pp: 472-478
Wei-tao Gong*, Wei-dong Qu and Guiling Ning
DOI: 10.2174/1570180816666190801100603

One-Pot, Regioselective Synthesis of Homopropargyl Alcohols using Propargyl Bromide and Carbonyl Compound by the Mg-mediated Reaction under Solvent-free Conditions

Volume: 17   Issue: 6
Pp: 438-442
Xiaofang Ma*, Shunxi Li, Samrat Devaramani *, Guohu Zhao and Daqian Xu
DOI: 10.2174/1570178616666190926104037

Lipids and Free Fatty Acids of Red Sea Avrainvillea amadelpha, Holothuria atra, and Sarcocornia fruticosa Inhibit Marine Bacterial Biofilms

Volume: 17   Issue: 6
Pp: 466-471
Usama W. Hawas*, Fekri Shaher, Mohamed Ghandourah, Lamia T. Abou El-Kassem, Sathianeson Satheesh and Abdul Mohsin A. Al-Sofyani
DOI: 10.2174/1570178616666191004104031