Abstract
Keto-enol tautomerism has been the subject of continuous interest in chemistry. Enols and enolate ions are essential intermediates in many important chemical reactions, and a number of biological transformations also involve enol formation. Enolization, moreover, has long been of interest as an example of tautomeric rearrangement. One of the things that one would like to know about enols is the magnitude of keto (KH) / enol (EH) equilibrium constants (KH EH, KE). This tautomeric equilibrium has been studied for many years and a large number of methods have been applied for investigating the keto-enol conversion. We review some of the work that we have been doing in the field of keto-enol / enolate equilibria characterization and on enol reactivity in constrained media, such as aqueous solutions of surfactants forming micelles or cyclodextrins. A recently developed method of studying keto-enol equilibrium that combines the UV-vis spectroscopy and aqueous solutions of organized microstructures will be presented. The emphasis of the exposition is the comparative analysis of the several methods used in continuing research to evaluate keto-enol equilibrium constants, by paying detailed attention to the difficulties, and advantages / disadvantages of this new method in comparison with previous others. Therefore, after a brief description of common properties of 1,3- dicarbonyl compounds and of micro-organized media, we report studies of keto-enol / enolate equilibria and the methods and techniques used.
Keywords: Keto-Enol Equilibrium, dicarbonyl, micro-organized
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
22