Recent Patents on Anti-Cancer Drug Discovery

Lentiviral-Mediated Beclin-1 Overexpression Inhibits Cell Proliferation and Induces Autophagy of Human Esophageal Carcinoma Eca109 Cell Xenograft in Nude Mice

Volume: 15   Issue: 1
Pp: 70-77
Junhe Zhang* and Weihua Dong
DOI: 10.2174/1574892814666191211130342

Expression of B Cell Translocation Gene 1 Protein in Colon Carcinoma and its Clinical Significance

Volume: 15   Issue: 1
Pp: 78-85
Junhe Zhang* and Weihua Dong
DOI: 10.2174/1574892815666200109113114

Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years

Volume: 15   Issue: 1
Pp: 2-13
Hongyu Tao, Ling Zuo, Huanli Xu, Cong Li, Gan Qiao, Mingyue Guo and Xiukun Lin*
DOI: 10.2174/1574892815666200131120618

SOX4 Serves an Oncogenic Role in the Tumourigenesis of Human Breast Adenocarcinoma by Promoting Cell Proliferation, Migration and Inhibiting Apoptosis

Volume: 15   Issue: 1
Pp: 49-58
Junhe Zhang*, Shujie Chai and Xinyu Ruan
DOI: 10.2174/1574892815666200212112119

Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitors: A Patent Review (2016-2019)

Volume: 15   Issue: 1
Pp: 32-48
Xingrui He, Zhen Li, Xiao-Tao Zhuo, Zi Hui, Tian Xie* and Xiang-Yang Ye*
DOI: 10.2174/1574892815666200217125419

Feasibility of Repurposing Clioquinol for Cancer Therapy

Volume: 15   Issue: 1
Pp: 14-31
Raheel Khan, Harras Khan, Yassen Abdullah and Q. Ping Dou*
DOI: 10.2174/1574892815666200227090259

Increased NID1 Expression among Breast Cancer Lung Metastatic Women; A Comparative Analysis between Naive and Treated Cases

Volume: 15   Issue: 1
Pp: 59-69
Tabinda Urooj*, Bushra Wasim, Shamim Mushtaq, Ghulam Haider, Syed N.N. Shah, Rubina Ghani and Muhammad F.H. Qureshi
DOI: 10.2174/1574892815666200302115438

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Volume: 15   Issue: 1
Pp: 1-1
Paolo Chieffi
DOI: 10.2174/157489281501200401124257

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Volume: 15   Issue: 1
Pp: 86-89

DOI: 10.2174/157489281501200401134340

The Molecular Docking of Flavonoids Isolated from Daucus carota as a Dual Inhibitor of MDM2 and MDMX

Volume: 15   Issue:
Pp: 1-11
Ijaz Muhammad, Noor Rahman, Gul E Nayab, Sadaf Niaz, Mohibullah Shah, Sahib Gul Afridi, Haroon Khan*, Maria Daglia and Esra Capanoglu
DOI: 10.2174/1574892815666200226112506

Bortezomib – First Therapeutic Proteasome Inhibitor for Cancer Therapy: A Review of Patent Literature

Volume: 15   Issue:
Pp: 1-20
Pratik Ashwinbhai Vora*, Rakesh Patel and Abhay Dharamsi
DOI: 10.2174/1574892815666200401113805

Recent Patents on the Development of c-Met Kinase Inhibitors

Volume: 15   Issue:
Pp: 1-11
Xiangming Xu and Lei Yao*
DOI: 10.2174/1574892815666200630102344

Modulation of MicroRNAs by Euphorbia Microsciadia Boiss in MDA-MB- 231 Cell Line:New Possibilities in Breast Cancer Therapy

Volume: 15   Issue:
Pp: 1-11
Mohammad-Reza Mahmoudian-Sani and Majid Asadi-Samani*
DOI: 10.2174/1574892815666200630102944

Autophagy and Ubiquitination as Two Major Players in Colorectal Cancer: A Review on Recent Patents

Volume: 15   Issue:
Pp: 1-11
Javad Saffari-Chaleshtori, Majid Asadi-Samani, Maryam Rasouli and Sayed Mohammad Shafiee*
DOI: 10.2174/1574892815666200630103626

Recent Patents on Anticancer Potential of Helenalin

Volume: 15   Issue:
Pp: 1-11
Priyanka Kriplani* and Kumar Guarve
DOI: 10.2174/1574892815666200702142601

Cancer Stem Cells and their Management in Cancer Therapy

Volume: 15   Issue:
Pp: 1-16
Suzan Shenouda, Ketan Kulkarni, Yasser Abuetabh and Consolato Sergi *
DOI: 10.2174/1574892815666200713145931

Anticancer Potential of Aguerin B, a Sesquiterpene Lactone Isolated from Centaurea behen in Metastatic Breast Cancer Cells

Volume: 15   Issue:
Pp: 1-9
Elaheh Amini, Mohammad Nabiuni, Seyed Bahram Behzad, Danial Seyfi, Farhad Eisvand, Amirhossein Sahebkar* and Abolfazl Shakeri
DOI: 10.2174/1574892815666200713162304

The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer

Volume: 15   Issue:
Pp: 1-13
XiaoLing Fu*, YanBo Zhang, Lisheng Chang, DengCheng Hu, Ru Jia, NingNing Liu, HuaYue Zhang, Gang Han, ZhiFen Han, Yuan Li, Hui Liu, Huirong Zhu and Qi Li
DOI: 10.2174/1574892815666200717141205

Developments in the Application of 1,2,3-Triazoles in Cancer Treatment

Volume: 15   Issue:
Pp: 1-21
Katerina I. Slavova, Lozan T. Todorov*, Nataliya P. Belskaya, Mauricio Alcolea Palafox and Irena P. Kostova
DOI: 10.2174/1574892815666200717164457

Mechanism of a Novel Camptothecin-Deoxycholic Acid Derivate Induced Apoptosis against Human Liver Cancer HepG2 Cells and Human Colon Cancer HCT116 Cells

Volume: 14   Issue: 4
Pp: 370-382
Linxia Xiao, Jialin Xu, Qi Weng, Leilei Zhou, Mengke Wang, Miao Liu and Qingyong Li*
DOI: 10.2174/1574892814666191016162346

MDM2-p53 Interaction Inhibitors: The Current State-of-Art and Updated Patent Review (2010-Present)

Volume: 14   Issue: 4
Pp: 324-369
Rafał Rusiecki, Jakub Witkowski* and Jaszczewska-Adamczak Joanna
DOI: 10.2174/1574892814666191022163540

Chimeric Antigen Receptor-Engineered T-Cells - A New Way and Era for Lymphoma Treatment

Volume: 14   Issue: 4
Pp: 312-323
Romeo G. Mihăilă*
DOI: 10.2174/1574892814666191022164641

Apigenin, A Plant Flavone Playing Noble Roles in Cancer Prevention Via Modulation of Key Cell Signaling Networks

Volume: 14   Issue: 4
Pp: 298-311
Deepti Singh, Mohammad A. Khan and Hifzur R. Siddique*
DOI: 10.2174/1574892814666191026095728

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Volume: 14   Issue: 4
Pp: 295-295
Frank Entschladen
DOI: 10.2174/157489281404191220160818

Toward a Personalized Use of Paclitaxel promotion: free to download

Volume: 14   Issue: 4
Pp: 296-297
Gian L. Russo*
DOI: 10.2174/157489281404191220161014

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Volume: 14   Issue: 4
Pp: 383-385

DOI: 10.2174/157489281404191220161118

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Volume: 14   Issue: 4
Pp: 386-386

DOI: 10.2174/157489281404191220161218

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Volume: 14   Issue: 4
Pp: 387-387

DOI: 10.2174/157489281404191220161252

Safety Profiles and Pharmacovigilance Considerations for Recently Patented Anticancer Drugs: Lung Cancer

Volume: 14   Issue: 3
Pp: 242-257
Alessandra Bearz, Sara Cecco, Sara Francescon, Francesco Lo Re, Giuseppe Corona and Paolo Baldo*
DOI: 10.2174/1574892814666190726124735

Safety Profiles and Pharmacovigilance Considerations for Recently Patented Anticancer Drugs: Cutaneous Melanoma

Volume: 14   Issue: 3
Pp: 203-225
Debora Basile, Camilla Lisanti, Maria A. Pizzichetta, Paolo Baldo*, Giulia Fornasier, Francesco Lo Re, Giuseppe Corona and Fabio Puglisi
DOI: 10.2174/1574892814666190726130351

Safety Profiles and Pharmacovigilance Considerations for Recently Patented Anticancer Drugs: Advanced Thyroid Cancer

Volume: 14   Issue: 3
Pp: 226-241
Emanuela Vaccher, Ornella Schioppa, Ferdinando Martellotta, Giulia Fornasier, Elisa Giacomin, Francesco Lo Re, Paolo Baldo*, Giuseppe Corona and Carlo Gobitti
DOI: 10.2174/1574892814666190726143011

Association between hTERT Polymorphisms and Female Papillary Thyroid Carcinoma

Volume: 14   Issue: 3
Pp: 268-279
Ying Liu, Zhi Li, Xinyue Tang, Min Li and Feng Shi*
DOI: 10.2174/1574892814666190919145453

HMGA and Cancer: A Review on Patent Literatures

Volume: 14   Issue: 3
Pp: 258-267
Marco De Martino, Alfredo Fusco and Francesco Esposito*
DOI: 10.2174/1574892814666190919152001

Tissue Distribution and Systemic Toxicity Evaluation of Raloxifene Targeted Polymeric Micelles of Poly (Styrene-Maleic Acid)-Poly (Amide- Ether-Ester-Imide)-Poly (Ethylene Glycol) Loaded With Docetaxel in Breast Cancer Bearing Mice

Volume: 14   Issue: 3
Pp: 280-291
Jaleh Varshosaz*, Farshid Hassanzadeh, Batool Hashemi-Beni, Mohsen Minaiyan and Saeedeh Enteshari
DOI: 10.2174/1574892814666190919163731

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Volume: 14   Issue: 3
Pp: 201-201
Anna Sapino
DOI: 10.2174/157489281403191028142655

Safety Profiles and Pharmacovigilance Considerations for Recently Patented / Approved Anticancer Drugs promotion: free to download

Volume: 14   Issue: 3
Pp: 202-202
Paolo Baldo
DOI: 10.2174/157489281403191028143024

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Volume: 14   Issue: 3
Pp: 292-294

DOI: 10.2174/157489281403191028143330

Novel Small Molecule Inhibitors of Programmed Cell Death (PD)-1, and its Ligand, PD-L1 in Cancer Immunotherapy: A Review Update of Patent Literature

Volume: 14   Issue: 2
Pp: 100-112
Spandana R. Kopalli, Tae-Bong Kang, Kwang-Ho Lee and Sushruta Koppula*
DOI: 10.2174/1574892813666181029142812

Cucurbitacins as Anticancer Agents: A Patent Review

Volume: 14   Issue: 2
Pp: 133-143
Hidayat Hussain*, Ivan R. Green, Muhammad Saleem, Khanzadi F. Khattak, Muhammad Irshad and Maroof Ali
DOI: 10.2174/1574892813666181119123035

Death-Associated Protein Kinase 1 as a Promising Drug Target in Cancer and Alzheimer’s Disease open access plus

Volume: 14   Issue: 2
Pp: 144-157
Dongmei Chen, Xiao Z. Zhou* and Tae H. Lee*
DOI: 10.2174/1574892814666181218170257

Lentiviral-Mediated Overexpression of MicroRNA-141 Promotes Cell Proliferation and Inhibits Apoptosis in Human Esophageal Squamous Cell Carcinoma

Volume: 14   Issue: 2
Pp: 170-176
Jun-He Zhang and Hai-Bin Xia*
DOI: 10.2174/1574892814666181231142136

Enzyme and Transporter Kinetics for CPT-11 (Irinotecan) and SN-38: An Insight on Tumor Tissue Compartment Pharmacokinetics Using PBPK

Volume: 14   Issue: 2
Pp: 177-186
Yingfang Fan, Najia Mansoor*, Tasneem Ahmad, Zhuo X. Wu, Rafeeq A. Khan, Martin Czejka, Syed Sharib, Mansoor Ahmed, Zhe S. Chen and Dong H. Yang*
DOI: 10.2174/1574892814666190212164356

Repurposing Disulfiram as An Anti-Cancer Agent: Updated Review on Literature and Patents

Volume: 14   Issue: 2
Pp: 113-132
Elmira Ekinci, Sagar Rohondia, Raheel Khan and Qingping P. Dou*
DOI: 10.2174/1574892814666190514104035

Inhibitory Effect of Hydroxysafflor Yellow B on the Proliferation of Human Breast Cancer MCF-7 Cells

Volume: 14   Issue: 2
Pp: 187-197
Chuanjun Qu, Weiwei Zhu, Kaijie Dong, Zhaohai Pan, Ying Chen, Xiaoyu Chen, Xiaona Liu, Wenjuan Xu, Haiyan Lin, Qiusheng Zheng* and Defang Li*
DOI: 10.2174/1574891X14666190516102218

A Truncated Snail1 Transcription Factor Alters the Expression of Essential EMT Markers and Suppresses Tumor Cell Migration in a Human Lung Cancer Cell Line

Volume: 14   Issue: 2
Pp: 158-169
Mohammad Davoodzadeh Gholami, Reza Falak*, Sahel Heidari, Majid Khoshmirsafa, Mohammad H. Kazemi, Amir-Hassan Zarnani, Elaheh Safari, Nader Tajik and Gholam A. Kardar*
DOI: 10.2174/1574892814666190527111429

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Volume: 14   Issue: 2
Pp: 99-99
Olivier Micheau
DOI: 10.2174/157489281402190621124346

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Volume: 14   Issue: 2
Pp: 198-200

DOI: 10.2174/157489281402190621143002

Nanostructured Systems in Advanced Drug Targeting for the Cancer Treatment: Recent Patents

Volume: 14   Issue: 1
Pp: 85-94
Maricruz Anaya-Ruiz, Cindy Bandala, Gerardo Landeta, Patricia Martínez-Morales, Jose L. Zumaquero-Rios, Jorge Sarracent-Pérez and Martín Pérez-Santos*
DOI: 10.2174/1574892813666181031154146

High-throughput Strategy Accelerates the Progress of Marine Anticancer Peptide Drug Development promotion: free to download

Volume: 14   Issue: 1
Pp: 2-4
Peng Lyu and Hang F. Kwok*
DOI: 10.2174/1574892813999181114152127

Tobacco Smoking: Risk to Develop Addiction, Chronic Obstructive Pulmonary Disease, and Lung Cancer open access plus

Volume: 14   Issue: 1
Pp: 39-52
Alessia Santoro, Carlo Tomino, Giulia Prinzi, Palma Lamonaca, Vittorio Cardaci, Massimo Fini and Patrizia Russo*
DOI: 10.2174/1574892814666190102122848

Contemporary Formulations for Drug Delivery of Anticancer Bioactive Compounds open access plus

Volume: 14   Issue: 1
Pp: 19-31
Darinka G. Ackova, Katarina Smilkov and Darko Bosnakovski*
DOI: 10.2174/1574892814666190111104834

New Anti-Cancer Strategies in Testicular Germ Cell Tumors open access plus

Volume: 14   Issue: 1
Pp: 53-59
Paolo Chieffi*, Marco De Martino and Francesco Esposito
DOI: 10.2174/1574892814666190111120023

Chimeric Antigen Receptor T Cell Immunotherapy for Tumor: A Review of Patent Literatures open access plus

Volume: 14   Issue: 1
Pp: 60-69
Manxue Fu and Liling Tang*
DOI: 10.2174/1574892814666190111120908

Tocotrienols and Cancer: From the State of the Art to Promising Novel Patents open access plus

Volume: 14   Issue: 1
Pp: 5-18
Fabrizio Fontana, Michela Raimondi, Monica Marzagalli, Roberta M. Moretti, Marina Montagnani Marelli and Patrizia Limonta*
DOI: 10.2174/1574892814666190116111827

Purinergic P2X7 Receptor: A Cation Channel Sensitive to Tumor Microenvironment open access plus

Volume: 14   Issue: 1
Pp: 32-38
Giorgia Scarpellino, Tullio Genova and Luca Munaron*
DOI: 10.2174/1574892814666190116122256

From Antimicrobial to Anticancer Peptides: The Transformation of Peptides open access plus

Volume: 14   Issue: 1
Pp: 70-84
Yuan Qin, Zuo D. Qin, Jing Chen, Che G. Cai, Ling Li, Lu Y. Feng, Zheng Wang, Gregory J. Duns, Nong Y. He, Zhe S. Chen* and Xiao F. Luo*
DOI: 10.2174/1574892814666190119165157

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Volume: 14   Issue: 1
Pp: 1-1
Domenico Ribatti
DOI: 10.2174/157489281401190218122947

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Volume: 14   Issue: 1
Pp: 95-98

DOI: 10.2174/157489281401190218123225

PARP Inhibitors in Ovarian Cancer

Volume: 13   Issue: 4
Pp: 392-410
Gloria Mittica, Eleonora Ghisoni, Gaia Giannone, Sofia Genta, Massimo Aglietta, Anna Sapino and Giorgio Valabrega*
DOI: 10.2174/1574892813666180305165256

Recent Progress of Marine Polypeptides as Anticancer Agents

Volume: 13   Issue: 4
Pp: 445-454
Lanhong Zheng, Yixin Xu, Xiukun Lin*, Zhixin Yuan, Minghua Liu, Shousong Cao, Fuming Zhang and Robert J. Linhardt
DOI: 10.2174/1574892813666180430110033

Targeting Metabolism to Counteract Tumor Angiogenesis: A Review of Patent Literature open access plus

Volume: 13   Issue: 4
Pp: 422-427
Sara Petrillo, Emanuela Tolosano, Luca Munaron and Tullio Genova*
DOI: 10.2174/1574892813666180528105023

Amplified Crosstalk Between Estrogen Binding and GFR Signaling Mediated Pathways of ER Activation Drives Responses in Tumors Treated with Endocrine Disruptors open access plus

Volume: 13   Issue: 4
Pp: 428-444
Zsuzsanna Suba*
DOI: 10.2174/1574892813666180720123732

Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency open access plus

Volume: 13   Issue: 4
Pp: 469-472
Georgy Y. Nadysev, Alexander S. Tikhomirov, Lyubov G. Dezhenkova and Andrey E. Shchekotikhin*
DOI: 10.2174/1574892813666180723150542

Journey Describing the Cytotoxic Potential of Withanolides: A Patent Review

Volume: 13   Issue: 4
Pp: 411-421
Hidayat Hussain*, Rene Csuk, Ivan R. Green, Najeeb Ur Rehman, Ghulam Abbas and Wahid Hussain
DOI: 10.2174/1574892813666180808154928

Recent Advances In Developing Novel Anti-Cancer Drugs Targeting Tumor Hypoxic and Acidic Microenvironments

Volume: 13   Issue: 4
Pp: 455-468
Weidong Li and Xueying Sun*
DOI: 10.2174/1574892813666180831102519

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Volume: 13   Issue: 4
Pp: 391-391
Q. Ping Dou
DOI: 10.2174/157489281304180927111640

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Volume: 13   Issue: 4
Pp: 473-478

DOI: 10.2174/157489281304180927111831

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Volume: 13   Issue: 4
Pp: 479-479

DOI: 10.2174/157489281304180927111921

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Volume: 13   Issue: 4
Pp: 480-480

DOI: 10.2174/157489281304180927112018

The Application of lncRNAs in Cancer Treatment and Diagnosis

Volume: 13   Issue: 3
Pp: 292-301
Yi Zhang and Liling Tang*
DOI: 10.2174/1574892813666180226121819

Oral Submucous Fibrosis as an Overhealing Wound: Implications in Malignant Transformation

Volume: 13   Issue: 3
Pp: 272-291
Mohit Sharma, Smitha S. Shetty and Raghu Radhakrishnan*
DOI: 10.2174/1574892813666180227103147

Stemness Phenotype in Tamoxifen Resistant Breast Cancer Cells May be Induced by Interactions Between Receptor Tyrosine Kinases and ERα-66

Volume: 13   Issue: 3
Pp: 302-307
Leila Farahmand, Sepideh Mansouri, Narges Jafarbeik-Iravani, Azin Teymourzadeh and Keivan Majidzadeh-A*
DOI: 10.2174/1574892813666180305164634

TC > 0.05 as a Pharmacokinetic Parameter of Paclitaxel for Therapeutic Efficacy and Toxicity in Cancer Patients

Volume: 13   Issue: 3
Pp: 341-347
D.S. Xin, L. Zhou, C.Z. Li, S.Q. Zhang, H.Q. Huang, G.D. Qiu, L.F. Lin, Y.Q. She, J.T. Zheng, C. Chen, L. Fang, Z.S. Chen* and S.Y. Zhang*
DOI: 10.2174/1574892813666180305170439

Low Dose of Acacetin Promotes Breast Cancer MCF-7 Cells Proliferation Through the Activation of ERK/ PI3K /AKT and Cyclin Signaling Pathway

Volume: 13   Issue: 3
Pp: 368-377
Huanhuan Ren, Jun Ma, Lingling Si, Boxue Ren, Xiaoyu Chen, Dan Wang, Wenjin Hao, Xuexi Tang, Defang Li* and Qiusheng Zheng*
DOI: 10.2174/1574892813666180420154012

Emerging Drugs for the Treatment of Breast Cancer Brain Metastasis: A Review of Patent Literature

Volume: 13   Issue: 3
Pp: 348-359
Maricruz Anaya-Ruiz, Cindy Bandala, Patricia Martinez-Morales, Gerardo Landeta, Rebeca D. Martinez-Contreras, Nancy Martinez-Montiel and Martin Perez-Santos*
DOI: 10.2174/1574892813666180430113605

Synthesis, In Silico and In Vitro Cytostatic Activity of New Lipophilic Derivatives of Hydroxyurea

Volume: 13   Issue: 3
Pp: 378-385
Zeynab Khansefid, Asghar Davood*, Maryam Iman and Mahdi Fasihi
DOI: 10.2174/1574892813666180517102255

Evolving Strategies for the Treatment of T-Cell Lymphoma: A Systematic Review and Recent Patents

Volume: 13   Issue: 3
Pp: 308-340
Kamel Laribi*, Mustapha Alani, Catherine Truong and Alix Baugier de Materre
DOI: 10.2174/1574892813666180517102801

CS5931, A Novel Marine Polypeptide, Inhibits Migration and Invasion of Cancer Cells Via Interacting with Enolase 1

Volume: 13   Issue: 3
Pp: 360-367
Shuonan Su, Huanli Xu, Xiaoliang Chen, Gan Qiao, Ammad A. Farooqi, Ye Tian, Ru Yuan, Xiaohui Liu, Cong Li, Xiao Li, Ning Wu and Xiukun Lin*
DOI: 10.2174/1574892813666180628170240

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Volume: 13   Issue: 3
Pp: 271-271
Anupam Bishayee
DOI: 10.2174/157489281303180716104358

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Volume: 13   Issue: 3
Pp: 386-390

DOI: 10.2174/157489281303180716104820

Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins open access plus

Volume: 13   Issue: 2
Pp: 184-200
Federica Iannelli, Rita Lombardi, Maria R. Milone, Biagio Pucci, Simona De Rienzo, Alfredo Budillon* and Francesca Bruzzese*
DOI: 10.2174/1574892812666171129141211

PARP Inhibitors in Epithelial Ovarian Cancer open access plus

Volume: 13   Issue: 2
Pp: 145-158
Kristin N. Taylor and Ramez N. Eskander*
DOI: 10.2174/1574892813666171204094822

Advances in the Discovery of Anthraquinone-Based Anticancer Agents

Volume: 13   Issue: 2
Pp: 159-183
Alexander S. Tikhomirov*, Alexander A. Shtil and Andrey E. Shchekotikhin
DOI: 10.2174/1574892813666171206123114

Reduced Lipocalin 2 Expression Contributes to Vincristine Resistance in Human Colon Cancer Cells

Volume: 13   Issue: 2
Pp: 248-254
Xiao Guo, Qin Li, Yan-Fang Wang, Tian-Yun Wang*, Si-Jia Chen and Zheng-Wei Tian
DOI: 10.2174/1574892813666171221120504

Anaplastic Lymphoma Kinase in Glioblastoma: Detection/Diagnostic Methods and Therapeutic Options open access plus

Volume: 13   Issue: 2
Pp: 209-223
Theodosis Kalamatianos, Despoina Denekou, George Stranjalis and Evangelia Papadimitriou*
DOI: 10.2174/1574892813666180115151554

Anti-Oxidants as Chemopreventive Agents in Prostate Cancer: A Gap Between Preclinical and Clinical Studies

Volume: 13   Issue: 2
Pp: 224-239
Monireh Mohsenzadegan*, Farhad Seif, Mohammad M. Farajollahi and Majid Khoshmirsafa
DOI: 10.2174/1574892813666180213164700

Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation open access plus

Volume: 13   Issue: 2
Pp: 133-144
Juan F. Santibanez* and Suncica Bjelica
DOI: 10.2174/1574892813666180220105958

Lenvatinib in the Therapy of Aggressive Thyroid Cancer: State of the Art and New Perspectives with Patents Recently Applied open access plus

Volume: 13   Issue: 2
Pp: 201-208
Silvia M. Ferrari, Ilaria Ruffilli, Marco Centanni, Camilla Virili, Gabriele Materazzi, Magdalini Alexopoulou, Mario Miccoli, Alessandro Antonelli* and Poupak Fallahi
DOI: 10.2174/1574892813666180220110729

Synthesis and DFT Study on Hantzsch Reaction to Produce Asymmetrical Compounds of 1,4-Dihydropyridine Derivatives for P-Glycoprotein Inhibition as Anticancer Agent

Volume: 13   Issue: 2
Pp: 255-264
Shirin Mollazadeh, Fatemeh Moosavi, Farzin Hadizadeh*, Mahmoud Seifi, Javad Behravan and Maryam Iman*
DOI: 10.2174/1574892813666180220112613

Anti-Cancer Effect of α-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells

Volume: 13   Issue: 2
Pp: 240-247
Xiaofen Ni, Jiajun Chen, Fengying Lu, Zhengzhong Yuan, Xiaofeng Xu, Zhen Hu* and Lei Jiang*
DOI: 10.2174/1574892813666180329163945